Abstract
Favre−Racouchot disease (FRD) is an occupational disorder characterized by solar elastosis with open and cystically dilated comedones that tend to appear on the periorbital and temporal face of elderly light-complexioned men. It is a benign condition caused by chronic excessive ultraviolet exposure, as well as ionizing radiation and/or smoking. However, malignant skin neoplasms are uncommonly observed arising in FRD, which suggests a protective role of some element of FRD against carcinogenesis. We explore elastosis as a possibly beneficial tissue response. The clinical manifestations, pathogenesis, and recommended treatment options of this disorder are reviewed.
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Yeh, C., Schwartz, R.A. Favre−Racouchot disease: protective effect of solar elastosis. Arch Dermatol Res 314, 217–222 (2022). https://doi.org/10.1007/s00403-021-02202-5
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DOI: https://doi.org/10.1007/s00403-021-02202-5