Abstract
Introduction
Hip arthroplasty is exposed to demographic change as patients age. Analysis of risk factors for surgical treatment decisions in the group of ≥ 80-year-old patients is crucial. Healthcare systems in developed countries are being tested medically and financially by the ageing population. Therefore, this study analysed the perioperative complications of cementless primary hip arthroplasty in octogenarians and compared them with patients aged ≤ 60 years.
Methods
A retrospective data analysis of the year 2017 was done in a maximum care hospital of General Orthopaedic Surgery. Patients aged ≥ 80 years or ≤ 60 years with primary cementless hip arthroplasty were included. The outcome of interest was surgery-related and systemic complications, the development of haemoglobin and the incidence of blood transfusion after cementless primary hip arthroplasty in octogenarians during the hospitalisation and the follow-up treatment. Chi-square tests and Fischer's exact test were used for nominal variables. The two-factorial variance analysis-mixed model was used for Hb analyses and the Welch test for group comparison for metric parameters.
Results
There was a significantly increased incidence of systemic complications during hospitalisation in the ≥ 80-year-old patients (phi 0.26; Std. Ri − 0.8 (A), 2.2 (B); p = 0.007), as well as a significantly increased rate of blood transfusions (phi 0.403; Std. Ri − 1.3 (A), 3.2 (B); p = < 0.001). No clustered pre-existing conditions in the ≥ 80-year-old patients pointed out a significant association with the incidence of systemic complications. Surgery-related complications showed no significant difference during hospitalisation and follow-up treatment.
Conclusion
The study reveals that primary cementless hip prosthesis implantation is a safe procedure without increased incidence of surgery-related complications. Increased attention should be paid to interdisciplinary preoperative optimisation (adjustment of blood pressure, blood transfusions, if necessary, safe exclusion of urinary tract infections) and postoperative care of octogenarians (tight laboratory examinations, geriatric co-attendance).
Similar content being viewed by others
Avoid common mistakes on your manuscript.
Introduction
The overall age of the population in industrial countries is increasing, and therefore, the prevalence of end-stage degenerative joint diseases [1]. Therefore, the number of arthroplasties performed on octogenarians is expected to increase [2]. Total hip arthroplasty (THA) aims to restore the function and biomechanics of the hip joint [3]. However, such a procedure in octogenarians may be associated with enhanced complications. Reduced performance status and lower preoperative haemoglobin have been described as risk factors [4]. In octogenarians, an increased rate of cognitive dysfunction and deep vein thrombosis have been demonstrated. In addition, cardiovascular and urogenital complications were also reported. Octogenarians seem to be more susceptible to anaesthesia- and surgery-associated mortality in major surgeries [5,6,7]. Some studies showed a slow survival probability for endoprosthesis in octogenarians. [8, 9]. The management of complications in elderly patients can be lengthy. The possibility of potentiating events over the inpatient treatment can lead to responsive medicine. To our knowledge, no other retrospective study has directly compared perioperative complications between a particularly young versus a particularly old patient group. Furthermore, no other study combined local, surgical, and systemic complications, as well as blood transfusion frequencies.
This study was initiated to identify possible common complications of octogenarians undergoing primary hip arthroplasty to take preventive measures in clinical practice. Possible prolonged inpatient hospital stays due to infections; mobility disorders or surgical complications should thus be reduced. Therefore, summarising of the main complications of surgical and systemic nature was done. Subsequently, the complications were compared with age-typical pre-existing diseases. Local, surgical, and systemic complications were recorded. Furthermore, the frequency of blood transfusions was investigated. Afterwards, all data was compared between young patients under the age of 60 and octogenarians. It was hypothesised that perioperative complications, as well as blood transfusions, were more common in octogenarians.
Materials and methods
Patient recruitment
The present study was conducted according to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement [10]. A retrospective data analysis of the year 2017 was done in the Department of Orthopaedic Surgery of the RUB university hospital Auguste-Viktoria-Klinik. 356 primary cementless hip arthroplasties were done in 2017. All data came from a house intern archiving program and were available in electronic form. Access to the surgical progression, duration of stay in the hospital and post-hospital documentation for patients was possible through the program. Data collection was done over 5 months from November 2018 to March 2019.
Eligibility criteria
The inclusion criteria were (1) age 80 years and older or 60 years and younger, (2) cementless hip arthroplasty of the cup and stem, (3) patients with primary elective hip arthroplasties, (4) standard minimal invasive anterolateral approach, and (5) implantation of the Allofit-System and femoral Fitmore® stem (Fa. Zimmer Biomet Freiburg GE). The exclusion criteria were (1) ages between 61 and 79, (2) revision hip arthroplasties, (3) cemented hip arthroplasties, (4) different approach than anterolateral, (5) different type of cup and stem, (6) intraoperative change of method, stem and cup, and (7) incorrect documented patient files pre-, intra-, postoperative and in the follow-up treated. The data of the patients were collected chronologically in the excel spreadsheet.
Surgical procedure
Surgical procedures were performed by 12 surgeons. Anterolateral approach, Fitmore® stem as well as pre-and postoperative management was done for all patients.
The surgical procedure was performed in a lateral position using a minimally invasive technique. An incision was made from the greater trochanter in the direction of the SIAS (spina iliaca anterior superior). After cutting the muscle fascia, the gluteus medius muscle was retracted to provide a clear view of the joint capsule. After the preparation of the capsule, the two-stage osteotomy was performed, first near the femoral head and then at the level of the trochanteric fossa. After removal of the head, preparation of the acetabulum was performed with a press fit cup implantation. Turning towards the femur: here, the medullary canal is displaced by utilising a fine rasp. After implantation of the trial stem and the head, trial implantation was performed. If the conditions were stable and the leg length was correct, the final prosthesis was implanted. In the rehabilitation phase, immediate full mobilisation without restrictions was performed with the help of physiotherapy.
Data assessment
Categorisation of the patient cohort into two age groups (A < 60 years; B ≥ 80 years) was done, based on a monocentric, retrospective case–control study. The period of documentation in the follow-up treatment for group A was about 151 ± 147 days, for group B about 88 ± 84 days.
Outcome of interest
Preoperative data: the age, the gender, the BMI, the length of the hospital stay, the duration of the surgery, the operating doctor, pre-existing conditions, visual analogic scale and nicotine use were recorded. Intraoperative data: the size and type of cup, the inlay and stem were collected. Postoperative data: haemoglobin, surgery-related complications like open and closed reposition, periprosthetic fracture, dislocation, leg length difference, delayed wound healing, nerve lesion and systemic complications (urinary infection, embolism, thrombosis, infarction, myocardial infarction, arrhythmia, pneumonia, pulmonary oedema, renal insufficiency, abdominal complications), as well as the influence on an increased blood transfusion incidence, were examined. In the follow-up treatment, documented surgical revisions, interventions and infections were collected. Failure was defined as an intraoperative change of the implant, a different approach than anterolateral, mortality during hospitalisation and follow-up treatment. Pre-existing conditions that occurred more frequently in old age were investigated in addition with the systemic complications. Data were assessed after the cases were closed and after documented follow-up treatment.
Statistical analysis
Data were collected using Microsoft® Excel® for Office 365 and statistical analysis was performed using IBM® SPSS® 28 (Armonk, New York, USA). Continuous variables were described by median and quartiles, means and standard deviations. Absolute and relative frequencies were used to represent categorical variables. Nominal variables were analysed by Chi-square tests and by Fischer’s exact test. The effect size was measured using phi (0.10 small effect; 0.3 middle effect; 0.5 high effect) and standardised residuals (> 2, regardless of minus or plus, shows a meaningful effect). The two-factorial variance analysis-mixed model was used to compare group differences. The effect size was determined by squared Eta (0.01 small effect; 0.06 middle effect; 0.14 high effect). The p values reported should be understood as descriptive measures. The Welch test for independent samples was used for group comparisons for metric parameters. The effect size was determined by Cohen’s d (0.20 small effect; 0.50 middle effect; 0.80 high effect). The significance level was set two sided with α = 0.05.
Results
Enrolment process
A total of 350 patients were initially screened. 223 of the patients were between 61 and 79 years old (n = 223). 127 patients were suitable for the study. 51 patients were 80 years and older and compared with 76 patients 60 years and younger. In one case, a BHR® system was initially implanted. Intraoperatively, the surgeon decided to switch to a Fitmore® stem. The prosthesis was treated as a revision prosthesis and, therefore, dropped from the evaluation (n = 1). 126 patients were left for the investigation. 51 patients were 80 years and older and 75 patients were 60 years and younger (Fig. 1). All patients underwent primary cementless hip arthroplasty. In the follow-up treatment some patients could not be considered due to missing documentation (n = 15). For the follow-up analysis in Group A ≤ 60-year-old patients n = 66 were left, and in Group B ≥ 80-year-old patients n = 44 were left.
Demographic data
We analysed the data of 126 patients during hospitalisation and 110 patients during the follow-up treatment. Overall, 56.34% (71 of 126) were women, and 43.66% (55 of 126) were men. The mean age in group A was 51.8 years and in group B 83.3 years. The mean BMI in group A was 29.37 kg/m2 and in group B 26.62 kg/m2. The mean ASA-Score (American Society of Anaesthesiologists) in group A was 1.70 and in group B 2.45. The mean hospitalisation was 9 days for group A and 10 days for group B. Hospital stay between age groups differed significantly with longer stay for patients 80 years and older (df 82,407; d = 0.531; p = 0.008). The main follow-up treatment of group A was 170 days and 100 days for group B (Table 1).
Systemic and surgical complications
Hospitalisation
Table 2 shows the occurrence of systemic and surgery-related complications during the hospitalisation.
Systemic complications
In total, systemic complications occurred in 11 patients (8.73%) during their hospital stay (Table 3). With 9 patients (17.6%), group B showed the highest incidence of complications and showed significant differences compared to group A 2.6% (n = 2) (p = 0.007).
Surgery-associated complications
There was no statistically significant difference of complications in need of revision between group A and B (Tables 4, 5). In group A, there were 2.6% (n = 2) and in group B 5.9% (n = 3). Likewise, there was no statistically significant difference of complications without the need of revision between group A and B. In group A, there were 4% (n = 3) and in group B 0% (n = 0).
Follow-up
Table 6 shows the occurrence of surgery-related complications during follow-up treatment.
Surgery-associated complications
Surgery-associated complications
In total, surgery-associated complications during the follow-up treatment occurred with 3.0% (n = 2) in Group A and 6.8% (n = 3) in group B (Tables 7, 8). There was no statistically difference between the groups. Likewise, there was no statistically significant difference of complications without the need of revision between group A and B. In group A, there were 1.5% (n = 1) and in group B 6.8% (n = 3).
Preconditions and systemic complications
Arterial hypertension occurred in 76.47% (n = 39) of group B and 37.33% (n = 28) in group A. No statistical association between arterial hypertension and the occurrence of systemic complications was found (p = 0.06). Antithrombotic medication, which was taken in 52.94% (n = 27) of group B compared to group A 1.33% (n = 1) did not point out to be a significant factor for systemic complications (p = 0.772). ASA-Score > 3, which appeared in 49.01% (n = 25) in group B and 6.6% (n = 5) in group A did not influence systemic complications (p = 0.291). Likewise, no statistical correlation to systemic complications could be found in renal insufficiency, which was only detected in group B at 21.56% (n = 11). Arrhythmia was not associated with a risk of systemic complications (p = 0.226). In 31.37% (n = 16) of the patients in group B and 10.66% (n = 8) in group A, arrhythmia was described. Furthermore, a statistical association between the BMI > 30 and nicotine consumption with systemic complications was investigated (Table 9). Both pre-existing conditions occurred more frequently in group A (BMI > 30 = 41.33%; n = 31; NC = 28%; n = 21) than group B (BMI > 30 = 15.68%; n = 8; NC = 3.92%; n = 2). There was no statistical association between systemic complication and the BMI > 30 or nicotine consumption (BMI > 30 p = 1; NC p = 0.687).
Development of haemoglobin and transfusion
The development of haemoglobin (Hb) within the age groups could be taken from routine laboratory tests. Values before an operation and before the discharge from hospital (day 1, day 7) were compared. Preoperatively, age group B showed a value of 133.73 g/l (SD 12.89) in comparison to group A and 145.10 g/l (SD 11.92) in those under 60 years of age. The Hb drop 1 day after surgery was not significantly different between groups A and B (p = 0.321). For measuring the Hb drop between preoperative and Day 7, we analysed group A n = 59 and group B n = 46, because of missing values for day 7 of 16 patients in group A and 5 patients in group B. The Hb drop from preoperative to day 7 postoperative was not significantly different between groups A and B (p = 0.889). According to the WHO Criteria, there were 69.33% of patients in group A and 90,19% of patients in group B with persisting anaemia on day 7 (Table 10). Postoperative transfusion of blood occurred significantly more often in group B (31.4%) than in group A (2.7%) (p < 0.001) during hospitalisation.
Discussion
Regarding the current study, a difference in the frequency of systemic complications was observed between the group of patients aged ≤ 60 years and the group of patients aged ≥ 80 years. However, there was no significant difference in the comparison of pre-existing conditions, which are more common in older individuals, to systemic complications. Likewise, no significant difference was found for surgical complications or local complications during hospitalisation and the follow-up treatment. The study of the haemoglobin drop showed no significant difference between the two age groups. A significant difference was found in the rate of blood transfusions required.
In the context of demographic change and increasing demands on the quality of life, geriatric patients place high demands on arthroplasty. Currently, the problems and treatment options in hip arthroplasty in a patient 80 years and older are discussed [11, 12].
Arthroplasty in patients over 75 years of age is performed with both cementless and cemented anchorage. There is a controversial discussion about the failure probability and service life of endoprosthesis in elderly patients. Nanjayan et al. showed a higher incidence of cardiovascular disease and pneumonia for octogenarians after THA. Yohe et al. examined the risk of readmission to hospital and complications within 30 days for patients ≥ 80 years. In their investigation, chronic obstructive pulmonary disease was the only comorbidity, which increased the risk for readmission to the hospital. Overall, patients above the age of 80 showed more major and minor complications after THA. Furthermore, octogenarians have been shown to have an increased risk of urogenital infections, as well as postoperative delirium [13, 14]. Urinary tract infections were also common in our study. Prolonged use of a bladder catheter in older patients could increase the risk compared to younger patients due to possible delayed mobility postoperatively. In addition, certain pre-existing conditions could also be generally well controlled by the general practitioner. Kelly et al. 2022 documented cause-specific revision risks by implantation method, age, and gender. There was a high risk of periprosthetic fractures for female patients ≥ 75 for cementless hip arthroplasty in comparison to hybrid implantation. In contrast, no significant differences in the incidence of complications related to older age were found in other studies [8, 9]. Other investigators showed a lower risk of dislocation in a 5-year follow-up treatment for octogenarians with cementless stem and dual mobility cups [15, 16]. Tsukada et al. demonstrated a 93% survival rate in a 14-years follow-up treatment for cementless hip arthroplasty with ceramic-on-alumina ceramic components [17]. The condition of materials and the combination can also affect the risk of surgery-related complications. In this study, comparatively very few patients showed perioperative surgery-related complications. The reason could be the established standardised implantation technique for primary hip arthroplasty. The surgical routine may create safety during the operation and, therefore, enables a higher quality, also in the training. Other studies showed a prolonged hospitalisation of older patients; however, a generally worse outcome could not be proven [16, 18]. The hospitalisation in this investigation differed significantly between the age groups. Delayed mobility, due to postoperative delirium, which was not investigated in this study, or continued immobilising pain due to other joints could be relevant here. Standardised, structured hospital processes from surgery to discharge management are thus once again proving to be relevant. Despite the investigation of differences between young and old patients, there are several comparisons between octogenarians and nonagenarians undergoing THA and TKA. The outcome between octogenarians and nonagenarians differed in favour of patients younger than 90 years. Postoperative complications and mortality were increased in the older comparison group in some studies [6, 19]. In this study, octogenarians showed a higher ASA-Score (2.45), but there was no statistical significance to systemic complications (ASA-Score > 3; p = 0.291). This is in line with McConaghy et al. who described that the ASA-Score cannot predict minor and major complications [20]. Several studies described a relationship between age and cardiac complications [21,22,23]. Waterman et al. and Belmont et al. reported increased odds of cardiac complications for patients ≥ 80 years (OR 4.39; 95% CI 2.29–6.61; p < 0.001 and OR 3.72; CI 95% 1.53–9.06; p = 0.0001) [24, 25]. Dugdale et al. showed hospital mortality of 0.18% and a postoperative infection rate of 0.04% for 147.281 patients in a nationwide research. 24% of the patients needed a blood transfusion. With regards to blood transfusions, current data analyses show that patients over 80 years of age are affected significantly more frequently than younger patients [14, 26, 27]. On the other hand, Hourly et al. showed 0% blood transfusion rate after primary total hip arthroplasty for 153 patients aged about 77 years during hospitalisation. In this investigation blood transfusion in the group of ≥ 80 patients were more common. As the haemoglobin drop was similar in both groups, one explanation could be the more frequent occurrence of clinical symptoms in patients over 80 years of age. Furthermore, an age-related delayed healing tendency compared to younger patients could be the cause. Maybe, a computer-generated system, which could give a fast and individual risk analysis of patients could help to prevent perioperative complications. Kunze et al. were able to build a test system, which had a good predictive capability of about 0.88 (AUC = area under the curve) [28]. However, further investigations with a higher number of patients and further testing of digital intelligence should be performed.
This study has several limitations. The limited number of patients included in the present investigation may limit the ability to detect uncommon complications. The lack of 16 patients in the follow-up treatment was not possible to close. For some patients, the availability of a telephone was not given and for others, we did not receive any feedback. Similar studies involving a larger population and longer follow-up treatments are required. Only the data for 2017 were evaluated. Some values of the visual analogue scale or laboratory results were missing. In 2017, the assessment of mobility and activity pre- and postoperatively was not performed uniformly by means of scores and thus could not be evaluated adequately. Due to the statistical evaluation of mainly nominal scaled values, multiple testing was not feasible in a meaningful way. There was no uniform scoring system for the admission to the hospital or the discharge from hospital of patients. The number of different operating doctors with different operating times could affect the results. Furthermore, no correction for multiple testing was made in the statistical analysis. The calculated p values only serve to describe the patient groups in detail and to show possible correlations. Some correlations showed a small to middle effect strength. The relatively small study group of ≥ 80-year-olds with only 51 patients bears the risks of not realistically representing possible differences between the groups due to the missing occurrence of events, as well as falsely representing differences that result solely from the random recording of individual events. Differences between complications and identified risk factors should, therefore, be validated on a larger sample. With the continued paucity of data on the internal medicine outcome of elderly patients after cementless metaphysical fixed prostheses, this work provided a valuable addition to the existing literature. The investigation of the long-term survival of these prostheses in elderly patients with poor bone quality is reserved for other studies.
Conclusion
Overall, the age group of ≥ 80 years carried a risk for the occurrence of internal (systemic) complications in the inpatient treatment compared to the other age group. There was no difference for surgical or local complications. Preconditions, which occur more often in elderly patients, did not report relation to systemic complications. There was no significant difference in the drop of haemoglobin. In this investigation, blood transfusion rates were more often in the group of ≥ 80-year-olds.
Change history
23 September 2022
A Correction to this paper has been published: https://doi.org/10.1007/s00402-022-04622-y
References
Sloan M, Premkumar A, Sheth NP (2018) Projected volume of primary total joint arthroplasty in the U.S., 2014 to 2030. J Bone Jt Surg Am 100(17):1455–1460
Christensen K et al (2009) Ageing populations: the challenges ahead. Lancet 374(9696):1196–1208
Learmonth ID, Young C, Rorabeck C (2007) The operation of the century: total hip replacement. Lancet 370(9597):1508–1519
Hanreich C et al (2022) Blood management following total joint replacement in an aging population: can we do better? J Arthroplasty 37(4):642–651
Nanjayan SK et al (2014) In-hospital complications following primary total hip and knee arthroplasty in octogenarian and nonagenarian patients. J Orthop Traumatol 15(1):29–33
Alfonso DT et al (2007) Total hip and knee arthroplasty in nonagenarians. J Arthroplasty 22(6):807–811
Jin F, Chung F (2001) Minimizing perioperative adverse events in the elderly. Br J Anaesth 87(4):608–624
Zimmerer A et al (2021) Midterm survivorship of an uncemented hydroxyapatite-coated titanium femoral component and clinically meaningful outcomes in patients older than 75 years. J Clin Med 10(5):1019
Zak SG et al (2021) Primary total hip arthroplasty outcomes in octogenarians. Bone Jt Open 2(7):535–539
von Elm E et al (2008) The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol 61(4):344–349
Riley SA et al (2016) Cementless tapered femoral stems for total hip arthroplasty in octogenarians. J Arthroplasty 31(12):2810–2813
Stihsen C et al (2017) Cementless total hip arthroplasty in octogenarians. J Arthroplasty 32(6):1923–1929
Kennedy JW et al (2013) Outcomes of total hip arthroplasty in the octogenarian population. Surgeon 11(4):199–204
Kelly MP et al (2022) Cause-specific stem revision risk in primary total hip arthroplasty using cemented vs cementless femoral stem fixation in a US cohort. J Arthroplasty 37(1):89-96 e1
Belgaïd V, Viste A, Fessy MH (2021) Cementless hydroxyapatite-coated stem with dual mobility and posterior approach in over-80 year-old patients with osteoarthritis: rates of dislocation and periprosthetic fracture at a mean 8 years’ follow-up. Orthop Traumatol Surg Res 108:103196
Lamo-Espinosa JM et al (2021) Cemented dual mobility cup for primary total hip arthroplasty in elder patients with high-risk instability. Geriatrics (Basel) 6(1):23
Tsukada S et al (2022) Uncemented total hip arthroplasty using alumina ceramic bearings at a minimum of 14 years of follow-up. Arch Orthop Trauma Surg 142(7):1689–1695
Murphy BPD, Dowsey MM, Choong PFM (2018) The impact of advanced age on the outcomes of primary total hip and knee arthroplasty for osteoarthritis: a systematic review. JBJS Rev 6(2):e6
Kitridis D et al (2022) Mortality and complication rates in nonagenarians and octogenarians undergoing total hip and knee arthroplasty: a systematic review and meta-analysis. Eur Geriatr Med 13(3):725–733. https://doi.org/10.1007/s41999-022-00610-y
McConaghy KM et al (2021) Can extant comorbidity indices identify patients who experience poor outcomes following total joint arthroplasty? Arch Orthop Trauma Surg. https://doi.org/10.1007/s00402-021-04250-y
Thornqvist C et al (2014) Body mass index and risk of perioperative cardiovascular adverse events and mortality in 34,744 Danish patients undergoing hip or knee replacement. Acta Orthop 85(5):456–462
Menendez ME et al (2015) A nationwide analysis of risk factors for in-hospital myocardial infarction after total joint arthroplasty. Int Orthop 39(4):777–786
Feng B et al (2018) The effect of previous coronary artery revascularization on the adverse cardiac events ninety days after total joint arthroplasty. J Arthroplasty 33(1):235–240
Waterman BR et al (2016) The total joint arthroplasty cardiac risk index for predicting perioperative myocardial infarction and cardiac arrest after primary total knee and hip arthroplasty. J Arthroplasty 31(6):1170–1174
Belmont PJ Jr et al (2014) Postoperative myocardial infarction and cardiac arrest following primary total knee and hip arthroplasty: rates, risk factors, and time of occurrence. J Bone Joint Surg Am 96(24):2025–2031
Jeschke E et al (2021) Blood transfusion and venous thromboembolism trends and risk factors in primary and aseptic revision total hip and knee arthroplasties: a nationwide investigation of 736,061 cases. Orthop Traumatol Surg Res 108:102987
Kreder HJ et al (2005) Arthroplasty in the octogenarian: quantifying the risks. J Arthroplasty 20(3):289–293
Kunze KN et al (2022) Development and internal validation of machine learning algorithms for predicting complications after primary total hip arthroplasty. Arch Orthop Trauma Surg. https://doi.org/10.1007/s00402-022-04452-y
Funding
Open Access funding enabled and organized by Projekt DEAL. None.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
None.
Ethical approval
Obtained.
Informed consent
Not required.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
About this article
Cite this article
Koettnitz, J., Jäcker, J., Migliorini, F. et al. The risk analysis of perioperative complications of cementless hip arthroplasty in octogenarians. Arch Orthop Trauma Surg 143, 3551–3559 (2023). https://doi.org/10.1007/s00402-022-04575-2
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00402-022-04575-2