Skip to main content
SpringerLink
Log in

Multiple sclerosis and amyloid deposits in the white matter of the brain

  • Case report
  • Published:
Acta Neuropathologica Aims and scope Submit manuscript

Abstract

We present the neuropathological findings in a female patient with clinically definite multiple sclerosis (MS), who at autopsy had multifocal amyloid deposits in the white matter of the brain without other signs of amyloidosis. The patient had relapsing/remitting MS between the ages of 26 and 45, and during her last 14 years she had a secondary chronic progressive form of MS. Previous reports of amyloid deposits in MS are reviewed and the possible relationship between amyloid deposits and the increased production of immunoglobulin free light chains in MS is discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Division of Pathology, Karolinska Institute, Huddinge Hospital, S-141 86 Huddinge, Sweden Tel.: 46-8-746 10 00; Fax: 46-8-779 55 20; e-mail: inne@patd01.hs.sll.se, , , , , , SE

    I. Nennesmo

  2. Department of Clinical Neuroscience and Family Medicine, Geriatric Section, Karolinska Institute, Huddinge Hospital, Huddinge, Sweden, , , , , , SE

    Nenad Bogdanovic

  3. Division of Pathology, Karolinska Institute, Huddinge Hospital, Huddinge, Sweden, , , , , , SE

    Anna-Lena Petrén

  4. Division of Neurology, Karolinska Institute, Huddinge Hospital, Huddinge, Sweden, , , , , , SE

    Sten Fredrikson

Authors
  1. I. Nennesmo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Nenad Bogdanovic
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Anna-Lena Petrén
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Sten Fredrikson
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Received: 25 March 1996 / Revised, accepted: 5 August 1996

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nennesmo, I., Bogdanovic, N., Petrén, AL. et al. Multiple sclerosis and amyloid deposits in the white matter of the brain. Acta Neuropathol 93, 205–209 (1997). https://doi.org/10.1007/s004010050604

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s004010050604

Search

Navigation