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NMR and DSC study of temperature-induced phase transition in aqueous solutions of poly(N-isopropylmethacrylamide-co-acrylamide) copolymers

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Abstract

Combination of 1H NMR spectroscopy and differential scanning calorimetry (DSC) was used to investigate temperature-induced phase transition in D2O solutions of poly(N-isopropylmethacrylamide-co-acrylamide) random copolymers. Both the NMR and DSC data showed dependence on the acrylamide (AAm) content in the copolymer; with increasing AAm content, the phase transition is shifted to higher temperatures, and both phase-separated fractions determined by NMR and change of the enthalpy determined by DSC decrease faster than the content of thermosensitive N-isopropylmethacrylamide (NIPMAm) units in the copolymer. NMR data were used to construct van't Hoff plots, and changes of the enthalpy ΔH and entropy ΔS, characterizing the phase transition, were determined. As it follows from comparison of NMR and DSC thermodynamical parameters (ΔH values), the size of the cooperative units (domains), undergoing the transition as a whole, decreases with increasing AAm content in the copolymer since the NIPMAm collapsed domains are separated by regions with hydrated AAm and surrounding NIPMAm sequences.

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Acknowledgments

Supports by the Czech Science Foundation (project 202/09/1281), Ministry of Education, Youth and Sports of the Czech Republic (grant SVV–2012–265305) and the Grant Agency of Charles University (grant 719812) are gratefully acknowledged. Authors would like to thank Dr. Vladimír Šubr for his determination of molecular weights of investigated samples.

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Authors and Affiliations

  1. Faculty of Mathematics and Physics, Charles University, V Holešovičkách 2, 18000, Prague 8, Czech Republic

    Julie Šťastná & Lenka Hanyková

  2. Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Heyrovsky Sq. 2, 16206, Prague 6, Czech Republic

    Jiří Spěváček

Authors
  1. Julie Šťastná
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  2. Lenka Hanyková
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  3. Jiří Spěváček
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Correspondence to Lenka Hanyková or Jiří Spěváček.

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Šťastná, J., Hanyková, L. & Spěváček, J. NMR and DSC study of temperature-induced phase transition in aqueous solutions of poly(N-isopropylmethacrylamide-co-acrylamide) copolymers. Colloid Polym Sci 290, 1811–1817 (2012). https://doi.org/10.1007/s00396-012-2701-3

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  • DOI: https://doi.org/10.1007/s00396-012-2701-3

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