Zusammenfassung
Die rasch wachsende Gruppe der Biologika stellt heute bereits einen unverzichtbaren Bestandteil bei der Behandlung von chronisch entzündlichen oder Autoimmunerkrankungen dar, nicht nur für bislang therapierefraktäre Krankheitsverläufe sondern auch, weil die Effektivität einer Therapie mit Biologika oftmals dem Ausmaß des konventionell erreichbaren Therapieerfolges überlegen ist, der Wirkungseintritt rascher erfolgt und das Therapierisiko geringer erscheint. Aus diesem Grunde soll mit der vorliegenden Stellungnahme eine aktualisierte Empfehlung zur Behandlung von Kindern und Jugendlichen erfolgen [6].
Summary
The group of biologics for the treatment of rheumatic diseases is continuously growing. They have become an important option not only for treatment of so far untreatable chronic inflammatory or rheumatic disease, but also for juvenile idiopathic arthritis. In addition, the velocity and the degree of improvement is better than with to conventional therapies. Furthermore, toxicity and risks seem to be lower with higher safety and compatibility. Although the data are scarce, they are widely used. Therefore, the German Arbeitsgemeinschaft Kinder- und Jugendrheumatologie is updating the current recommendation for the treatment of juvenile idiopathic arthritis using biologics [6].
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Horneff, G. Einsatz von Biologika bei der juvenilen idiopathischen Arthritis. Z Rheumatol 65, 152–158 (2006). https://doi.org/10.1007/s00393-005-0002-7
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DOI: https://doi.org/10.1007/s00393-005-0002-7