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Increased risk of diabetes following perianal abscess: a population-based follow-up study

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International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

Purpose

It remains unclear whether perianal abscess is a prediabetes condition or the initial presentation of type 2 diabetes. Using a population-based dataset, this study aimed to explore the risk of type 2 diabetes following perianal abscess.

Methods

We used data sourced from the Longitudinal Health Insurance Database 2000. In total, there were 1,419 adult patients with perianal abscess in the study group and 7,095 randomly selected subjects in the comparison group. Stratified Cox proportional hazards regressions were carried out to evaluate the association between being diagnosed with perianal abscess and receiving a subsequent diagnosis of diabetes within 5 years.

Results

Of the total 8,514 sampled subjects, the incidence rate of diabetes per 100 person-years was 1.87 (95 % confidence interval (CI) = 1.74–2.01); the rate among patients with perianal abscess was 3.00 (95 % CI = 2.60–3.43) and was 1.65 (95 % CI = 1.52–1.79) among comparison patients. Stratified Cox proportional hazards analysis revealed that patients with perianal abscess were more likely to have received a diagnosis of diabetes than comparison patients (hazard ratio = 1.80, 95 % CI = 1.50–2.16, p < 0.001) during the 5-year follow-up period after censoring cases that died from nondiabetes causes and adjusting for patient geographic location, urbanization level, monthly income, hypertension, coronary heart disease, hyperlipidemia, obesity, and alcohol abuse/alcohol dependence syndrome at baseline.

Conclusions

Our results suggest that patients with perianal abscess have a higher chance of contracting type 2 diabetes mellitus within the first 5 years following their diagnosis.

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Acknowledgements

This study is based in part on data from the National Health Insurance Research Database provided by the Bureau of National Health Insurance, Department of Health, Taiwan and managed by the National Health Research Institutes. The interpretations and conclusions contained herein do not represent those of the Bureau of National Health Insurance, Department of Health, or the National Health Research Institutes.

Conflict of interest

The authors have no conflicts of interest to declare.

Author information

Authors and Affiliations

  1. Division of General Surgery, Department of Surgery, Taipei Medical University Hospital, Taipei, Taiwan

    Po-Li Wei & Li-Jen Kuo

  2. Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

    Po-Li Wei & Li-Jen Kuo

  3. School of Public Health, Taipei Medical University, Taipei, Taiwan

    Joseph J. Keller

  4. School of Health Care Administration, Taipei Medical University, Taipei, Taiwan

    Herng-Ching Lin

  5. School of Health Care Administration, College of Medicine, Taipei Medical University, 250 Wu-Hsing St., Taipei, 110, Taiwan

    Herng-Ching Lin

Authors
  1. Po-Li Wei
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  2. Joseph J. Keller
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  4. Herng-Ching Lin
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Correspondence to Herng-Ching Lin.

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Wei, PL., Keller, J.J., Kuo, LJ. et al. Increased risk of diabetes following perianal abscess: a population-based follow-up study. Int J Colorectal Dis 28, 235–240 (2013). https://doi.org/10.1007/s00384-012-1519-2

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  • DOI: https://doi.org/10.1007/s00384-012-1519-2

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