Addiss DG, Schaffer N, Fowler BS, Tauxe RV (1990) The epidemiology of appendicitis and appendectomy in the United States. Am J Epidemiol 132:910–925
CAS
Article
Google Scholar
Andersson RE (2007) The natural history and traditional management of appendicitis revisited: spontaneous resolution and predominance of prehospital perforations imply that a correct diagnosis is more important than an early diagnosis. World J Surg 31:86–92
Article
Google Scholar
You H, Sweeney A, Cooper ML, VonPapen M, Innes J (2019) The management of diverticulitis:a review of the guidelines. Med J Aust. https://doi.org/10.5694/mja2.50276
Article
PubMed
Google Scholar
Svensson JF, Hall NJ, Eaton S, Pierro A, Wester T (2012) A review of conservative treatment of acute appendicitis. Eur J Pediatr Surg 22:185–94
CAS
Article
Google Scholar
Bollinger RR, Barbas AS, Bush EL, Lin SS, Parker W (2007) Biofilms in the large bowel suggest an apparent function of the human vermiform appendix. J Theor Biol 249:826–831
CAS
Article
Google Scholar
De Coppi P, Pozzobon M, Piccoli M, Gazzola MV, Boldrin L, Slanzi E, Destro R, Zanesco L, Zanon GF, Gamba P (2006) Isolation of mesenchymal stem cells from human vermiform appendix. J Surg Res 135(85):91
Google Scholar
Rawolle T, Reismann M, Minderjahn MI, Bassir C, Hauptmann K, Rothe K, Reismann J (2019) Sonographic differentiation of complicated from uncomplicated appendicitis. Br J Radiol 92(1099):20190102. https://doi.org/10.1259/bjr.20190102
Article
PubMed
Google Scholar
Rubér M, Andersson M, Petersson BF, Olaison G, Andersson RE, Ekerfelt C (2010) Systemic Th17-like cytokine pattern in gangrenous appendicitis but not in phlegmounous appendicitis. Surgery 147:366–372
Article
Google Scholar
Lindestam U, Almström M, Jacks J, Malmquist P, Lönnqvist PA, Jensen BL, Carlström M, Krmar RT, Svensson JF, Norberg Å, Fläring U (2019) Low plasma sodium concentration predicts perforated acute appendicitis in children: a prospective diagnostic accuracy study. Eur J Pediatr Surg. https://doi.org/10.1055/s-0039-1687870
Article
PubMed
Google Scholar
Kaneko K, Tsuda M (2004) Ultrasound-based decision making in the treatrment of acute appendicitis in children. J Pediatr Surg 39:1316–1320
Article
Google Scholar
Abes M, Petik B, Kazil S (2007) Nonoperative treatment of acute ppendicitis in children. J Pediatr Surg 42:1439–1442
Article
Google Scholar
Armstrong J, Merritt N, Jones S, Scott L, Bütter A (2014) Non-operative management of early, acute appendicitis in children: is it safe and effective. J Pediatr Surg 49:782–785
Article
Google Scholar
Koike Y, Uchida K, Matsushita K, Otake K, Nakazawa M, Inoue M, Kusunoki T, Tsukamoto Y (2014) Intraluminal appendiceal fluid is a predictive factor for recurrent appendicitis after initial successful non-operative management of uncomplicated appendicitis in pediatric patients. J Pediatr Surg 49:1116–1121
Article
Google Scholar
Gorter RR, van der Lee JH, Cense HA, Kneepkens CMF, Wijnen MHWA, Hof KH, Offringa M, Heij HA (2015) Initial antibiotic treatment for acute simple appendicitis in children is safe: short-term results from a multicenter, prospective cohort study. Surgery 157:916–923
Article
Google Scholar
Steiner Z, Buklan G, Stackievicz Gutermacher M, Eeez I (2015) Arole for conservative antibiotic treatment in eraly appendicitis in children. J Pediatr Surg 50:1566–1568
Article
Google Scholar
Svensson JF, Patkova B, Almström M, Naji H, Hall NJ, Eaton S, Pierro A, Wester T (2015) Nonoperative treatment with antibiotics versus surgery for acute nonperforated appendicitis in children. Ann Surg 261:67–71
Article
Google Scholar
Tanaka Y, Uchida H, Kawashima H, Fujiogi M, Takazawa S, Deie K, Amano H (2015) Long-term outcomes of operative versus nonoperative treatment for uncomplicated appendicitis. J Pediatr Surg 50:1893–1897
Article
Google Scholar
Hartwich J, Luks FI, Watson-Smith D, Kurkchubasche AG, Muratore CS, Wills HE, Tracy TF (2016) Nonoperative treatment of acute appendicitis in children: a feasibility study. J Pediatr Surg 51:111–116
Article
Google Scholar
Mahida JB, Lodwick DL, Nacion KM, Sulkowski JP, Leonhart KL, Cooper JN, Ambeba EJ, Deans KJ, Minneci PC (2016) High failure rate of nonoperative management of acute appendicitis with an appendicolith in children. J Pediatr Surg 51:908–911
Article
Google Scholar
Minneci PC, Mahida JB, Lodwick D, Sulkowski JP, Nacion KM, Cooper JN, Ambeba EJ, Moss RL, Deans KJ (2016) Effectivenss of patient choice in nonoperative vs surgical management of pediatric uncomplicated acute appendicitis. JAMA Surg 151:408–415
Article
Google Scholar
Caruso AM, Pane A, Garau R, Atzori P, Podda M, Casuccio A, Mascia L (2017) Acute appendicitis in children: not only surgical treatment. J Pediatr Surg 52:444–448
Article
Google Scholar
Bachur RG, Lipsett SC, Monuteaux MC (2017) Outcomes of nonoperative management of uncomplicated appendicitis. Pediatrics. https://doi.org/10.1542/peds.2017-0048
Article
PubMed
Google Scholar
Steiner Z, Buklan G, Stackievicz R, Gutermacher M, Litmanovitz I, Golani G, Arnon S (2017) Conservative treatment in uncomplicated acute appendicitis reassessment of practice safety. Eur J Pediatr 176:521–527
Article
Google Scholar
Mudri M, Coriolano K, Bütter A (2017) Cost analysis of non-operative managemrnt of acute appendicitis in children. J Pediatr Surg 52:791–794
Article
Google Scholar
Lee SL, Spence L, Mock K, Wu JX, Yan H, De Ugarte DA (2018) Expanding the inclusion criteria for non-operative management og uncomplicated appendicitis: outcomes and cost. J Pediatr Surg 53:42–47
Article
Google Scholar
Gorter RR, van der Lee JH, Heijsters FACJ, Cense HA, Bakx R, Kneepkens CMF, Wijnen MH, van der Steeg AFW, Hof KH, Offringa M, Heij HA (2018) Outcome of initially nonoperative treatment for acute simple appendicitis in children. J Pediatr Surg 53:1849–1854
Article
Google Scholar
Scott A, Lee SL, DeUgarte DA, Shew SB, Dunn JCY, Shekherdimian S (2018) Nonoperative management of appendicitis. Clin Pediatr 57:200–204
Article
Google Scholar
Abbo O, Trabiano C, Pinnagoda K, Kaci AA, Carfagna L, Mouttalib S, Combelles S, Vial J, Galinier P (2018) Non-operative management for uncomplicated appendicitis: an optio to consider. Eur J Pediatr Surg 28:18–21
Article
Google Scholar
Steiner Z, Buklan G, Gutermacher M, Litmanovitz I, Landa T, Arnon S (2018) Conservative antibiotic treatment for acute uncomplicated appendicitis is feasible. Peditr Surg Int 34:283–288
Article
Google Scholar
Knaapen M, van der Lee JH, Heij HA, van Heurn ELW, Bakx R, Gorter RR (2019) Clinical recovery in children with uncomplicated appendicitis undergoing non-operative treatment: secondary analysis of a prospective cohort study. Eur J Pediatr Surg 178:235–242
CAS
Article
Google Scholar
Kessler U, Mosbahi S, Walker B, Hau EM, Cotton M, Peiry B, Berger S, Egger B (2017) Conservative treatment versus surgery for uncomplicated appendicitis in childre: a systematic review and meta-analysis. Arch Dis Child 102:1118–1124
Article
Google Scholar
Georgiou R, Eaton S, Stanton M, Pierro A, Hall NJ (2017) Efficacy and safety of nonoperative treatment for acute appendicitis: a meta-analysis. Pediatrics 139(3):e20163003. https://doi.org/10.1542/peds.2016-3003
Article
PubMed
Google Scholar
Svensson JF, Patkova B, Almström M, Naji H, Wester T, Hall NJ, Eaton S, Pierro A (2017) Design of studies for antibiotic treatment of acute appendicitis in children: in support of RCTs. Ann Surg 266(1):6–7. https://doi.org/10.1097/SLA.000000000001291
Article
Google Scholar
Salminen P, Tuominen R, Paajanen H, Rautio T, Nordström P, Aarnio M, Rantanen T, Hurme S, Mecklin JP, Sand J, Virtanen J, Jartti A, Grönroos JM (2018) Five-year follow up of antibiotic therapy for uncomlicated acute appendicitis in the APPAC randomized clinical trial. JAMA 320:1259–1265
CAS
Article
Google Scholar
Sippola S, Grönroos J, Sallinen V, Rautio T, Nordström P, Rantanen T, Hurme S, Leppäniemi A, Meriläinen S, Laukkarinen J, Savolainen H, Virtanen J, Salminen P (2018) A randomised placebo-controlled double-blind multicentre trial comparing antibiotic therapy with placebo in the treatment of uncomplicated acute appendicitis: APPAC III trial study protocol. BMJ Open 8(11):e23623. https://doi.org/10.1136/bmjopen-2018-023623
Article
Google Scholar
Vanhatalo S, Munukka E, Sippola S, Jalkanen S, Gröroos J, Marttila H, Eerola E, Hurme S, Hakanen AJ, Salminen P, APPAC collaborative Study Group (2019) Prospective multicentre cohort trial on acute appendicitis and microbiota, aetiology and effects of antimicrobial treatment: study protocol for the MAPPAC (Microbiology Appendicitis Acuta). BMJ Open 9(9):e031137. https://doi.org/10.1136/bmjopen-2019-031137
Article
PubMed
PubMed Central
Google Scholar