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Long-term outcomes and quality of life after subtotal colectomy combined with modified Duhamel procedure for adult Hirschsprung’s disease

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Abstract

Background

Subtotal colectomy combined with modified Duhamel procedure (Jinling procedure) was used in patients with adult Hirschsprung’s disease (AHD) at Jinling Hospital in the last decade. The aim of this study is to evaluate the safety, effectiveness and quality of life of Jinling procedure for AHD.

Materials and methods

All the data are from the database of the Jinling Hospital Constipation Registry System. Primary outcomes, including safety (morbidity and adverse events), effectiveness (satisfaction rate, Wexner constipation scale (WCS) and bowel function score (BFS)) and gastrointestinal quality of life index (GIQLI), were all evaluated.

Results

Fifty-nine patients were available for this study and the mean postoperative period was 44 months. Seventeen major complications were found in 11 patients and most of the complications could be managed conservatively. A significant improvement in WCS, BFS and GIQLI at 6 months postoperatively was obtained.

Conclusion

Jinling procedure is safe and effective for AHD.

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Acknowledgments

We thank Jieshou Li, Qiurong Li, Fangnan Liu, Chun Tang, Chenyang Wang and Xiaobo Feng for fruitful discussion and advice on this project. The study was funded by Jiangsu Provincial Special Program of Medical Science (BL2012006) [44].

Conflict of interest

The authors have nothing to disclose.

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Authors and Affiliations

  1. Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, People’s Republic of China

    Lin Wang, Qi He & Ning Li

  2. Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, 305 East Zhongshan Road, Nanjing, 210002, Jiangsu, People’s Republic of China

    Jun Jiang & Ning Li

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  1. Lin Wang
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  2. Qi He
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Correspondence to Ning Li.

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Wang, L., He, Q., Jiang, J. et al. Long-term outcomes and quality of life after subtotal colectomy combined with modified Duhamel procedure for adult Hirschsprung’s disease. Pediatr Surg Int 30, 55–61 (2014). https://doi.org/10.1007/s00383-013-3423-4

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