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Recurring pediatric anaplastic ependymoma with rare peritoneal carcinomatosis: a case report and hypothesis of mechanism

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Abstract

Background

Although recurrent anaplastic ependymoma in pediatric patients is not uncommon, recurrent disease leading to widespread metastases to the peritoneum is extremely rare.

Case Report

We present a case of an 18-month old male who initially presented with posterior fossa anaplastic ependymoma, who then proceeded to present 1 year later with spinal recurrence, and then 2 years after that with widespread disease involving the intracranial ventricular system and peritoneum.

Conclusion

We posit that surgical interventions to treat primary and recurrent presentations in combination with a conduit to the peritoneum via a ventriculoperitoneal shunt contributed to the mechanisms of this complex case.

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Authors and Affiliations

  1. Department of Pediatric Oncology, Mayo Clinic Children’s Center, 200 First St. SW, Rochester, MN, USA

    Ruby G. Siada, Jonathan Schwartz & David J. Daniels

  2. Department of Neurologic Surgery, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA

    Victor M. Lu & David J. Daniels

  3. Department of Neurological Surgery, University of Miami Miller School of Medicine, 1095 NW 14th Terrace, Miami, FL, 33136, USA

    Victor M. Lu

Authors
  1. Ruby G. Siada
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  2. Victor M. Lu
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  3. Jonathan Schwartz
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  4. David J. Daniels
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Correspondence to Victor M. Lu or David J. Daniels.

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All authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this study.

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Siada, R.G., Lu, V.M., Schwartz, J. et al. Recurring pediatric anaplastic ependymoma with rare peritoneal carcinomatosis: a case report and hypothesis of mechanism. Childs Nerv Syst 37, 1021–1024 (2021). https://doi.org/10.1007/s00381-020-04814-0

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  • DOI: https://doi.org/10.1007/s00381-020-04814-0

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