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A rare association of right hemicerebral dysgenesis with congenital anophthalmia in a neonate

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Abstract

Congenital anophthalmia is rare and can occur due to various etiologies, including genetic defects, teratogenic exposures, and vascular disruptions. We report a rare case of right-sided congenital anophthalmia and hemicerebral dysgenesis in association with ipsilateral hemicerebral vascular dysgenesis in a neonate. Postnatal neuroimaging was conspicuous for a “bare orbit sign.” A unilateral cranial neurocristopathy was suspected to be an underlying etiopathology for such a diffuse defect.

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Authors and Affiliations

  1. Department of Pediatrics, University of South Alabama, Mobile, AL, USA

    Kanya Singhapakdi & Juan Gonzalez

  2. Department of Neurology, Child Neurology Division, University of South Alabama, Mobile, AL, USA

    Paul Maertens & Peter Soh

  3. Department of Pediatrics, Division of Neonatology, University of South Alabama, 1700 Center Street, Mobile, AL, 36604, USA

    Ramachandra Bhat & Om Prakash Jha

Authors
  1. Kanya Singhapakdi
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  2. Paul Maertens
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  3. Juan Gonzalez
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  4. Peter Soh
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  5. Ramachandra Bhat
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  6. Om Prakash Jha
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Corresponding author

Correspondence to Om Prakash Jha.

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The authors have declared that they have no conflict of interest.

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Conference presentation

A portion of the data was presented as a poster presentation at The American Society of Neuroimaging (ASN) meeting 2020, Atlanta, GA, USA.

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Singhapakdi, K., Maertens, P., Gonzalez, J. et al. A rare association of right hemicerebral dysgenesis with congenital anophthalmia in a neonate. Childs Nerv Syst 37, 329–334 (2021). https://doi.org/10.1007/s00381-020-04639-x

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  • DOI: https://doi.org/10.1007/s00381-020-04639-x

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