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Intracranial metastasis of neuroblastoma: in two different areas at the same time

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Abstract

Introduction

Neuroblastoma (NB) is the most common extracranial solid malignancy in children. The major cause of death from this cancer is metastasis of tumors, and metastasis can be seen in different areas of the body. Metastasis of NB occurs by hematogenous and lymphatic routes. Generally, brain metastases have been reported in only one area of the brain parenchyma.

Case report

A 4-year-old male patient was treated in our clinic due to the NB that settled in the intra-abdominal region, but the patient presented with headache and nausea approximately 5 months after completion of the treatment. Whereupon, cranial imaging was performed and two masses were detected in the bilateral frontal lobe, and then the patient underwent surgery. Metastatic NB diagnosis was confirmed histopathologically. The patient’s chemotherapy treatment is still ongoing.

Conclusion

We report the case of a male patient with two separate metastatic masses in the brain parenchyma, which occurred in two different areas at the same time.

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Authors and Affiliations

  1. Faculty of Medicine, Department of Pediatric Hematology and Oncology, Selcuk University, Konya, Turkey

    Dogan Kose & Yavuz Koksal

  2. Faculty of Medicine, Department of Pathology, Selcuk University, Konya, Turkey

    Pinar Karabagli

  3. Faculty of Medicine, Department of Radiation Oncology, Selcuk University, Konya, Turkey

    Güler Yavas

  4. Faculty of Medicine, Department of Neurosurgery, Selcuk University, Konya, Turkey

    Hakan Karabagli

Authors
  1. Dogan Kose
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  2. Pinar Karabagli
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  3. Güler Yavas
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  4. Hakan Karabagli
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  5. Yavuz Koksal
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Correspondence to Dogan Kose.

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Kose, D., Karabagli, P., Yavas, G. et al. Intracranial metastasis of neuroblastoma: in two different areas at the same time. Childs Nerv Syst 29, 1799–1802 (2013). https://doi.org/10.1007/s00381-013-2203-8

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  • DOI: https://doi.org/10.1007/s00381-013-2203-8

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