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Trigeminal artery: a review of normal and pathological features

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Abstract

Objects

Carotid–vertebrobasilar anastomoses—the trigeminal, otic, hypoglossal, and proatlantal intersegmental arteries—serve as transitory channels between primitive internal carotid arteries and bilateral longitudinal neural arterial plexus, which is the precursor of future basilar artery, when the human embryo reaches about 4-mm length.

Material and methods

Normal and/or abnormal morphofunctional aspects of the prenatal and postnatal forms of the trigeminal artery are described according to personal and literature data. Many arteries of similar origin and course are also noted in the differential diagnosis of the trigeminal artery.

Conclusions

The persistent primitive trigeminal artery, as the most commonly carotid–vertebrobasilar anastomosis, has a reported incidence of 0.03–2.2% in the literature. There is female sex predilection, and it may be discovered in patients of any age, on either side, and in association with many vascular variants. Although the significance of persistent primitive trigeminal artery regarding the development of an aneurysm or association with another pathological condition may not be clear, its (ab)normal morphology is the inspiration for anatomists, especially for neurosurgeons, before planning diagnostic and therapeutic procedures.

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References

  1. Abe K, Suzuki T (1964) Persistence of embryonic carotid–vertebrobasilar anastomoses. Folia Psychiatr Neurol Japonica 18:257–276

    Google Scholar 

  2. Abe T, Fujita S, Ozawa H, Kawamura N, Shimazu M, Ikeda H, Izumiyama H, Matsumoto K (2000) Haemorrhagic nonsecreting pituitary adenoma associated with persistent primitive trigeminal artery. Acta Neurochir (Wien) 142:1423–1424

    Article  CAS  Google Scholar 

  3. Agrawal D, Mahapatra AK, Mishra NK (2005) Fusiform aneurysm of a persistent trigeminal artery. Case report. J Clin Neurosci 12:500–503

    Article  PubMed  CAS  Google Scholar 

  4. Ahmad I, Tominaga T, Suzuki M, Ogawa A, Yoshimoto T (1994) Primitive trigeminal artery associated with cavernous aneurysm: case report. Surg Neurol 41:75–79

    Article  PubMed  CAS  Google Scholar 

  5. Ali S, Radaideh MM, Shaibani A, Russell EJ, Walker MT (2008) Persistent trigeminal artery terminating in the posterior inferior cerebellar artery: case report. Neurosurgery 62:E746–E748

    Article  PubMed  Google Scholar 

  6. Alleyne CH Jr, Krisht A, Yoo FK, Silverstein A, Colohan AR (1997) Bilateral persistent trigeminal arteries associated with cerebral aneurysms and aortic arch vessel anomaly. South Med J 90:434–438

    Article  PubMed  Google Scholar 

  7. Anderson RA, Sondheimer FK (1976) Rare carotid–vertebrobasilar anastomoses with notes on the differentiation between proatlantal and hypoglossal arteries. Neuroradiology 11:113–118

    Article  PubMed  CAS  Google Scholar 

  8. Apostolides PJ, Lawton MT, David CA, Spetzler RF (1997) Clinical images: persistent primitive trigeminal artery with and without aneurysm. Barrow Quarterly 13(4). http://www.thebarrow.org/Education_And_Resources/Barrow_Quarterly/204843

  9. Arakawa T, Koizumi M, Terashima T, Honma S, Kawai K, Kodama K, Miki A (2007) Two anatomical autopsy cases of direct communication between a persistent primitive trigeminal artery and an anterior inferior cerebellar artery. Ann Anat 189:489–498

    Article  PubMed  Google Scholar 

  10. Baskaya MK, Roberts R, Rivera E, Nanda A (2001) Persistent primitive trigeminal artery associated with posterior communicating artery aneurysm and hypoplastic vertebral artery. Surg Radiol Anat 23:169–171

    Article  PubMed  CAS  Google Scholar 

  11. Berger MS, Hosobuchi Y (1984) Cavernous sinus fistula caused by intracavernous rupture of a persistent trigeminal artery. Case report. J Neurosurg 61:391–395

    Article  PubMed  CAS  Google Scholar 

  12. Bernstein K, Teitelbaum GP, Herman B, Giannotta SL (1998) Coil embolization of a trigeminal–cavernous fistula. AJNR Am J Neuroradiol 19:1953–1954

    PubMed  CAS  Google Scholar 

  13. Binet EF, Young RF (1977) Bilateral persistent trigeminal arteries. Case report. J Neurosurg 47:619–622

    Article  PubMed  CAS  Google Scholar 

  14. Bosco D, Consoli D, Lanza PL, Plastino M, Nicoletti F, Ceccotti C (2010) Complete oculomotor palsy caused by persistent trigeminal artery. Neurol Sci 31:657–659

    Article  PubMed  Google Scholar 

  15. Boyko OB, Curnes JT, Blatter DD, Parker DL (1996) MRI of basilar artery hypoplasia associated with persistent primitive trigeminal artery. Neuroradiology 38:11–14

    Article  PubMed  CAS  Google Scholar 

  16. Caldemeyer KS, Carrico JB, Mathews VP (1998) The radiology and embryology of anomalous arteries of the head and neck. AJR 170:197–203

    PubMed  CAS  Google Scholar 

  17. Campbell RL, Dyken ML (1961) Four cases of carotid–basilar anastomosis associated with central nervous system dysfunction. J Neurol Neurosurg Psychiatr 24:250–253

    Article  PubMed  CAS  Google Scholar 

  18. Chambers AA, Lukin R (1975) Trigeminal artery connection to the posterior inferior cerebellar arteries. Neuroradiology 9:121–123

    Article  PubMed  CAS  Google Scholar 

  19. Chan DTM, Boet R, Yu S, Poon WS (2004) Trispan-assisted coiling of a wide-necked persistent trigeminal artery aneurysm. Acta Neurochir (Wien) 146:87–88

    Article  CAS  Google Scholar 

  20. Chidambaranathan N, Sayeed ZA, Sunder K, Meera K (2006) Persistent trigeminal artery: a rare cause of trigeminal neuralgia—MR imaging. Neurol India 54:226–227

    PubMed  CAS  Google Scholar 

  21. Davis RA, Wetzel N, Davis L (1956) An analysis of the results of intracranial vascular lesions by carotid artery ligation. Ann Surg 143:641–649

    Article  PubMed  CAS  Google Scholar 

  22. De Bondt B-J, Stokroos R, Casselman J (2007) Persistent trigeminal artery associated with trigeminal neuralgia: hypothesis of neurovascular compression. Neuroradiology 49:23–26

    Article  PubMed  Google Scholar 

  23. Dicuonzo F, Palma M, Fiume M, Scarpello R, Lefons V, Maghenzani M, Carella A (2008) Cerebrovascular disorders in the prenatal period. J Child Neurol 23:1260–1266

    Article  PubMed  Google Scholar 

  24. Dimmick SJ, Faulder KC (2009) Normal variants of the cerebral circulation at multidetector CT angiography. RadioGraphic 29:1027–1043

    Article  Google Scholar 

  25. Djindjian R, Hurth M, Bories J, Brunet P (1965) L'artére trigéminale primitive (Aspects artériographiques et signification à propos de 12 cas). La Presse Méd 73:2905–2910 (in French)

    CAS  Google Scholar 

  26. Eggers FM, Tomsick TA, Chambers AA, Lukin RR (1982) Aneurysms of persistent trigeminal arteries. Report of two cases. Neuroradiology 24:65–66

    Article  PubMed  CAS  Google Scholar 

  27. Ekinci G, Baltacioğlu F, Kiliç T, Çimşit Ç, Akpmar I, Pamir N, Erzen C (2001) A rare cause of hyperprolactinemia: persistent trigeminal artery with stalk-section effect. Eur Radiol 11:648–650

    Article  PubMed  CAS  Google Scholar 

  28. Enomoto T, Sato A, Maki Y (1977) Carotid–cavernous sinus fistula caused by rupture of a primitive trigeminal artery aneurysm. Case report. J Neurosurg 46:373–376

    Article  PubMed  CAS  Google Scholar 

  29. Flandroy P, Lacour P, Marsault C, Stevenaert A, Collignon J (1987) The intravascular treatment of a cavernous fistula caused by rupture of a traumatic carotid trigeminal aneurysm. Neuroradiology 29:308–311

    Article  PubMed  CAS  Google Scholar 

  30. Foerch C, Berkefeld J, Halbsguth A, Ziemann U, Neumann-Haefelin T (2006) Brain stem infarction caused by proximal internal carotid stenosis in a patient with a persisting primitive trigeminal artery. Cerebrovasc Dis 22:200–202

    Article  PubMed  Google Scholar 

  31. Fukuda M, Kameyama S, Takahashi H, Tanaka R (1998) Trigeminal neuralgia caused by the vertebral artery associated with primitive trigeminal artery and agenesis of the internal carotid artery: case report. Neurol Med Chir (Tokyo) 38:367–370

    Article  CAS  Google Scholar 

  32. Fuse T, Niwa Y, Harada S (2000) Local intraarterial fibrinolytic therapy for embolic stroke associated with vascular anomalies. Two case reports. Neurol Med Chir (Tokyo) 40:641–644

    Article  CAS  Google Scholar 

  33. Gannon WE, Kaplan HA (1961) Persistent trigeminal artery. A method for its demonstration. Radiology 77:839–841

    PubMed  CAS  Google Scholar 

  34. Gasecki AP, Fox AJ, Lebrun LH, Daneault N (1994) Bilateral occipital infarctions associated with carotid stenosis in a patient with persistent trigeminal artery. Stroke 25:1520–1523

    Article  PubMed  CAS  Google Scholar 

  35. Given CA II, Huang-Hellinger F, Baker MD, Chepuri NB, Morris PP (2001) Congenital absence of the internal carotid artery: case reports and review of the collateral circulation. AJNR Am J Neuroradiol 22:1953–1959

    PubMed  Google Scholar 

  36. Goyal M (2001) The tau sign. Radiology 220:618–619

    Article  PubMed  CAS  Google Scholar 

  37. Güner M, Erbayraktar SE (1996) Arteriovenous malformation and persistent trigeminal artery association: case report. Turk Neurosurg 6:33–36

    Google Scholar 

  38. Harman M, Kýymaz N, Ayakta H, Kayan M (2004) Compressive effect of large persistent trigeminal artery upon pituitary gland: importance of MRI and MRA. Eur J Radiol Extra 51:65–67

    Article  Google Scholar 

  39. Hattori T, Inoue S, Sakai N (1997) Fenestration of the basilar artery associated with persistent primitive trigeminal artery. Case report. Neurol Med Chir (Tokyo) 37:841–843

    Article  CAS  Google Scholar 

  40. Hinck VC, Gordy PD (1964) Persistent primitive trigeminal artery. One type of persistent carotid–basilar anastomosis. Radiology 83:41–45

    PubMed  CAS  Google Scholar 

  41. Huber G (1980) Intracranial carotid anastomosis and partial aplasia of an internal carotid artery. Neuroradiology 20:207–212

    Article  PubMed  CAS  Google Scholar 

  42. Huber P (1982) Radiologic anatomy and topography of cerebral vessels. In: Huber P (ed) Krayebühl/Yaşargil cerebral angiography, 2nd edn. Thieme, New York, pp 57–60

    Google Scholar 

  43. Hurst RW, Howard RS, Zager E (1998) Carotid cavernous fistula associated with persistent trigeminal artery: endovascular treatment using coil embolization. Skull Base Surg 8:225–228

    Article  PubMed  CAS  Google Scholar 

  44. Iancu D, Anxionnat R, Bracard S (2010) Brainstem infarction in a patient with internal carotid dissection and persistent trigeminal artery: a case report. BMC Med Imaging 10:14. http://www.biomedcentral.com/1471-2342/10/14)

  45. Ide M, Jimbo M, Yamamoto M, Hagiwara S (1996) Emergence of persistent primitive trigeminal artery into posterior cranial fossa via an unusually caudal site. Acta Neurochir (Wien) 138:1132–1133

    Article  CAS  Google Scholar 

  46. Ikushima I, Arikawa S, Korogi Y, Uehara H, Komohara Y, Takahashi M (2002) Basilar artery aneurysm treated with coil embolization via persistent primitive trigeminal artery. Cardiovasc Intervent Radiol 25:70–71

    Article  PubMed  Google Scholar 

  47. Ito J, Takeda N, Suzuki Y, Takeuchi S, Osugi S, Yoshida Y (1980) Anomalous origin of the anterior inferior cerebellar arteries from the internal carotid artery. Neuroradiology 19:105–109

    Article  PubMed  CAS  Google Scholar 

  48. Jaeger HJ, Mehring U-M, Gissler HM, Mathias KD (2000) Congenital absence of the internal carotid artery and the basilar artery with persistent trigeminal artery associated with corctation of the aorta. Case report. Eur Radiol 11:1805–1809

    Article  Google Scholar 

  49. Kalidindi RS, Balen F, Hassan A, Al-Din A (2005) Persistent trigeminal artery presenting as intermittent isolated sixth nerve palsy. Clin Radiol 60:515–519

    Article  PubMed  CAS  Google Scholar 

  50. Kandelj EI, Saribekian AS (1978) Sočetanie persistiruiuščej primitivnoj trigeminaljnoj arterii s anevrizmoj srednej mozgovoj arterii. Vopr Neirohir 2:50–52 (in Russian)

    Google Scholar 

  51. Khodadad G (1976) Persistent trigeminal artery in the fetus. Radiology 121:653–656

    PubMed  CAS  Google Scholar 

  52. Khodadad G (1977) Trigeminal artery and occlusive cerebrovascular disease. Stroke 8:177–181

    Article  PubMed  CAS  Google Scholar 

  53. Kida MY, Ishida H, Dodo Y, Ikeda K, Kobayashi D, Nonaka M (1990) A case of the persistent trigeminal artery. Sapporo Med J 59:629–633 (in Japanese)

    Google Scholar 

  54. Koch S, Romano JG, Forteza A (2002) Subclavian steal and a persistent trigeminal artery. J Neuroimaging 12:190–192

    Article  PubMed  Google Scholar 

  55. Komiyama M, Kitano S, Sakamoto H, Shiomi M (1998) An additional variant of the persistent primitive trigeminal artery: accessory meningeal artery—antero-superior cerebellar artery anastomosis associated with Moyamoya disease. Acta Neurochir (Wien) 140:1037–1042

    Article  CAS  Google Scholar 

  56. Kwon K-H, Kim KH, Jeon P, Byun HS, Kim JS, Hong S-C (2007) Endovascular treatment for a persistent trigeminal artery aneurysm presenting as isolated sixth nerve palsy. Neurointervention 2:113–116

    Google Scholar 

  57. Lee M-R, Chuang Y-M, Chen W-J, Lin C-P (2009) Meticulous blood pressure control is mandatory for symptomatic primitive trigeminal artery. Am J Emerg Med 27:634.e5–634.e7

    Article  Google Scholar 

  58. Lie TA (1972) Congenital malformations of the carotid and vertebral arterial systems, including the persistent anastomoses. In: Vinken PJ, Bruyn GW (eds) Handbook of clinical neurology, vol 12. North Holland, Amsterdam, pp 289–339

    Google Scholar 

  59. Lin W-C, Kung L-L, Hsieh W-Y, Liu G-C (2001) Variant of persistent primitive trigeminal artery associated with giant internal carotid artery pseudoaneurysm. Chin J Radiol 26:173–178

    Google Scholar 

  60. Loevner L, Quint DJ (1992) Persistent trigeminal artery in a patient with Sturge–Weber syndrome. AJR 158:872–874

    PubMed  CAS  Google Scholar 

  61. Luh GY, Dean BL, Tomsick TA, Wallace RC (1999) The persistent fetal carotid–vertebrobasilar anastomoses. AJR 172:1427–1432

    PubMed  CAS  Google Scholar 

  62. Maeshima S, Terada T, Masuo O, Nakai K, Itakura T, Komai N (1999) Multiple cerebral aneurysms with persistent primitive trigeminal artery. J Clin Neurosci 6:52–54

    Article  PubMed  CAS  Google Scholar 

  63. Manjunath KY (2001) Anomalous origin of the middle meningeal artery—a review. J Anat Soc India 50(2). http://www.indmedica.com/journals.php?journalid=8&issueid=32&articleid=394&action=article

  64. McKenzie JD, Dean BL, Flom RA (1996) Trigeminal–cavernous fistula: Saltzman anatomy revisited. AJNR Am J Neuroradiol 17:280–282

    PubMed  CAS  Google Scholar 

  65. Menkü A, Akdemir H, Tucer B, Kurtsoy A (2004) Ruptured aneurysm associated with persistent primitive trigeminal artery: report of a case with three dimensional CT angiographic evaluation. Turk Neurosurg 14:21–24

    Google Scholar 

  66. Merry GS, Jamieson KG (1977) Operative approach to persistent trigeminal artery producing facial pain and diplopia. Case report. J Neurosurg 47:613–618

    Article  PubMed  CAS  Google Scholar 

  67. Metry D, Heyer G, Hess C, Garzon M, Haggstrom A, Frommelt P, Adams D, Siegel D, Hall K, Powell J, Frieden I, Drolet B (2009) Consensus statement on diagnostic criteria for PHACE syndrome. Pediatrics 124:1447–1456

    Article  PubMed  Google Scholar 

  68. Mohammed MI, Johnny S, Sandhu JS, Wakhloo AK (2002) Stent-assisted coil placement in a wide-necked persistent trigeminal artery aneurysm with jailing of the trigeminal artery: a case report. AJNR Am J Neuroradiol 23:437–441

    PubMed  Google Scholar 

  69. Morioka M, Yoshida A, Yoshikawa M, Ushio Y (1996) Transient alpha coma following minor head trauma in a patient with primitive trigeminal artery—case report. Neurol Med Chir (Tokyo) 36:224–228

    Article  CAS  Google Scholar 

  70. Morita A, Fukushima T, Miyazaki S, Shimizu T, Atsuchi M (1989) Tic douloureux caused by primitive trigeminal artery or its variant. J Neurosurg 70:415–419

    Article  PubMed  CAS  Google Scholar 

  71. Morrison G, Hegarty WM, Brausch CC, Castele TJ, White RJ (1974) Direct surgical obliteration of a persistent trigeminal artery aneurysm. Case report. J Neurosurg 39:249–251

    Google Scholar 

  72. Murai Y, Kobayashi S, Tateyama K, Teramoto A (2006) Persistent primitive trigeminal artery aneurysm associated with cerebellar hemangioblastoma—case report. Neurol Med Chir (Tokyo) 46:143–146

    Article  Google Scholar 

  73. Myint PK, Anderson KN, Antoun NM, Warburton EA (2008) Eyelid apraxia associated with bilateral paramedian thalamic infarct. Age Ageing 37:343–344

    Article  PubMed  Google Scholar 

  74. Nakai Y, Yasuda S, Hyodo A, Yanaka K, Nose T (2000) Infratentorial arteriovenous malformation associated with persistent prinitive trigeminal artery—case report. Neurol Med Chir (Tokyo) 40:572–574

    Article  CAS  Google Scholar 

  75. Naruse S, Odake G (1979) Primitive trigeminal artery associated with an ipsilateral intracavernous giant aneurysm—a case report. Neuroradiology 17:259–264

    Article  PubMed  CAS  Google Scholar 

  76. Nielsen BP, Jonson M (1967) Persistent primitive trigeminal artery demonstrated by vertebral arteriography. Radiology 101:47–51

    CAS  Google Scholar 

  77. Nishio A, Nishijima Y, Komiyama M, Hara M (2001) Primitive trigeminal variant aneurysm treated with Guglielmi detachable coils. Neurol Med Chir (Tokyo) 41:446–449

    Article  CAS  Google Scholar 

  78. Öertel O (1922) Über die persistenz embryonaler verindungen zwischen der A. carotis interna und der vertebralis cerebralis. Verh Anat Ges 55:281–295

    Google Scholar 

  79. Ohshiro S, Inoue T, Hamada Y, Matsuno H (1993) Branches of the persistent primitive trigeminal artery—an autopsy case. Neurosurgery 32:144–148

    Article  PubMed  CAS  Google Scholar 

  80. Ohtakara K, Kuga Y, Murao K, Kojima T, Taki W, Waga S (2000) Posterior fosa arteriovenous malformation associated with persistent primitive trigeminal artery—case report. Neurol Med Chir (Tokyo) 40:169–172

    Article  CAS  Google Scholar 

  81. Oka Y, Sadamoto K, Tagawa M, Kumon Y, Sakaki S, Fujita M (2000) Transvenous embolization of carotid–cavernous fistula associated with a primitive trigeminal artery—case report. Neurol Med Chir (Tokyo) 40:61–64

    Article  CAS  Google Scholar 

  82. Okada Y, Shima T, Nishida M, Yamada T, Yamane K, Okita S, Kagawa R (1992) Bilateral persistent trigeminal arteries presenting with brain-stem infarction. Neuroradiology 34:283–286

    Article  PubMed  CAS  Google Scholar 

  83. Okahara M, Kiyosue H, Mori H, Tanoue S, Sainou M, Nagatomi H (2002) Anatomic variations of the cerebral arteries and their embryology: a pictorial review. Eur Radiol 12:2548–2561

    PubMed  Google Scholar 

  84. Okanishi T, Saito Y, Miki S et al (2007) Lower brainstem dysfunction in an infant with persistent primitive trigeminal artery. Brain Dev 29:189–192

    Article  PubMed  Google Scholar 

  85. Onizuka M, Kazekawa K, Tsutsumi M et al (2006) Hyperform remodeling balloon for the balloon occlusion test of persistent primitive trigeminal artery aneurysm—case report. Neurol Med Chir (Tokyo) 46:541–543

    Article  Google Scholar 

  86. Oran I, Parildar M, Memis A, Yunten N (2000) Catheter and MR angiography of persistent trigeminal artery associated with occipital arteriovenous malformation. Comput Med Imaging Graph 24:33–35

    Article  PubMed  CAS  Google Scholar 

  87. O'uchi E, O'uchi T (2010) Persistent primitive trigeminal arteries (PTA) and its variant (PTAV): analysis of 103 cases detected in 16,415 cases of MRA over 3 years. Neuroradiology 52:1111–1119

    Article  PubMed  Google Scholar 

  88. Paksoy Y, Seker M, Kalkan E (2004) Klippel–Feil syndrome associated with persistent trigeminal artery. Spine 29:E193–E196

    Article  PubMed  Google Scholar 

  89. Parkinson D, Shields CB (1974) Persistent trigeminal artery: its relationship to the normal branches of the cavernous carotid artery. J Neurosurg 40:244–248

    Article  PubMed  CAS  Google Scholar 

  90. Pascual-Castroviejo I, Lopez-Gutierrez JC (2007) Cutaneous hemangioma associated with persistence of the trigeminal and both proatlantal arteries. J Child Neurol 22:337–340

    Article  PubMed  CAS  Google Scholar 

  91. Pereira LP, Nepomuceno LAM, Coimbra PP, Neto SRO, Natal MRC (2009) Persistent trigeminal artery. Angio-tomography and angio-magnetic resonance finding. Arq Neuropsiquiatr 67:882–885

    Article  PubMed  Google Scholar 

  92. Piotin M, Miralbés S, Cattin F, Marchal H, Amor-Sahli M, Moulin T, Bonneville JF (1996) MRI and MR angiography of persistent trigeminal artery. Neuroradiology 38:730–733

    Article  PubMed  CAS  Google Scholar 

  93. Quain R (1844) The anatomy of the arteries of the human body and its applications to pathology and operative surgery, with a series of lithographic drawings. Taylor and Walton, London

    Google Scholar 

  94. Quencer RM, Simon J (1979) Transient bilateral occipital lobe ischemia: embolization through a trigeminal artery. Neuroradiology 18:273–275

    Article  PubMed  CAS  Google Scholar 

  95. Raphaeli G, Bandeira A, Mine B, Brisbois D, Lubicz B (2009) A rare variant of persistent trigeminal artery: cavernous carotid–cerebellar artery anastomosis—a case report and a systematic review. Cerebellum 8:445–447

    Article  PubMed  Google Scholar 

  96. Rhee SJ, Kim MS, Lee CH, Lee GJ (2007) Persistent trigeminal artery variant detected by conventional angiography and magnetic resonance angiography. Incidence and clinical significance. J Korean Neurosurg Soc 42:446–449

    Article  PubMed  Google Scholar 

  97. Romero JM, Lev MH, Chan S-T, Connelly MM, Curiel RC, Jackson AE, Gonzales RG, Ackerman RH (2002) US of neurovascular occlusive disease: interpretive pearls and pitfalls. RadioGraphics 22:1165–1176

    PubMed  Google Scholar 

  98. Salas E, Ziyal IM, Sekhar LN, Wright DC (1998) Persistent trigeminal artery: an anatomic study. Neurosurgery 43:557–561 (Abstract)

    Article  PubMed  CAS  Google Scholar 

  99. Saltzman GF (1959) Patent primitive trigeminal artery studied by cerebral angiography. Acta Radiol (Stockh) 51:329–336

    Article  CAS  Google Scholar 

  100. Samra K, Scoville WB, Yaghmai M (1969) Anastomosis of carotid and basilar arteries. Persistent primitive trigeminal and hypoglossal artery: report of two cases. J Neurosurg 30:622–625

    Article  PubMed  CAS  Google Scholar 

  101. Schlamann M, Doerfler A, Schoch B, Forsting M, Wanke I (2006) Balloon-assisted coil embolization of a posterior cerebral artery aneurysm via a persistent primitive trigeminal artery: technical note. Neuroradiology 48:931–934

    Article  PubMed  Google Scholar 

  102. Schmid AH (1974) Persistent trigeminal artery. An autopsy report. Neuroradiology 7:173–176

    Article  PubMed  CAS  Google Scholar 

  103. Schwartz NE, Albers GW (2007) Acute strokes in the setting of a persistent primitive trigeminal artery. J Neurol Neurosurg Psychiatry 78:745

    Article  PubMed  Google Scholar 

  104. Seemann JH (2005) Coil embolization for sixth cranial nerve palsy caused by persistent primitive trigeminal artery. The Internet J Neurosurgery 2(2). http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijns/vol2n2/ppta.xml

  105. Shigemori M, Shirahama M, Yamamoto F, Hara K, Tokutomi T, Nakashima O (1980) Primitive trigeminal artery and intracranial carotid occlusion—case report. Kurume Med J 27:263–268

    Article  PubMed  CAS  Google Scholar 

  106. Shin YS, Kim SY, Kim BM, Park SI (2005) Ruptured aneurysm of the anomalous cerebellar artery originating from internal carotid artery presenting with carotid cavernous fistula: a case report. AJNR Am J Neuroradiol 26:1849–1851

    PubMed  Google Scholar 

  107. Silver JM, Wilkins RH (1991) Persistent embryonic intracranial and extracranial vessels. In: Wilkins RH, Rengachary SS (eds) Neurosurgery update II: Vascular, spinal, pediatric, and functional neurosurgery. McGraw-Hill, Health Professions Divisions, New York, pp 50–58

    Google Scholar 

  108. Singh RK, Varshney S, Bist SS, Burathoki S, Gupta N (2008) Anomalous internal carotid artery and persistent trigeminal artery. J Anat Soc India 57:140–143

    Google Scholar 

  109. Streeter GL (1918) The developmental alterations in the vascular system of the brain of the human embryo. Contr Embryol Carneg Instn 8:5–38

    Google Scholar 

  110. Suttner N, Mura J, Tedeschi H, Ferreira ATM, Wen HT, de Oliveira E, Rhoton AL Jr (2000) Persistent trigeminal artery: a unique anatomic specimen—analysis and therapeutic implications. Neurosurgery 47:428–434

    Article  PubMed  CAS  Google Scholar 

  111. Sutton D (1950) Anomalous carotid–basilar anastomosis. Brit J Radiol 23:617–619

    Article  PubMed  CAS  Google Scholar 

  112. Suzuki S, Morioka T, Matsushima T, Ikezaki K, Hasuo K, Fukui M (1996) Moyamoya disease associated with persistent primitive trigeminal artery variant in identical twins. Surg Neurol 45:236–240

    Article  PubMed  CAS  Google Scholar 

  113. Suzuki S, Chang GY (2010) A case of primitive trigeminal artery infarction. Neurology 75:S66

    Article  PubMed  Google Scholar 

  114. Szdzuy D, Lehmann R (1971) Persistent trigeminal artery in vertebral angiography. Neuroradiology 2:100–101

    Article  PubMed  CAS  Google Scholar 

  115. Takase T, Tanabe H, Kondo A, Nonoguchi N, Tane K (2004) Surgically treated aneurysm of the trunk of the persistent primitive trigeminal artery—case report. Neurol Med Chir (Tokyo) 44:420–423

    Article  Google Scholar 

  116. Tamura Y, Shimano H, Kuroiwa T, Miki Y (2003) Trigeminal neuralgia associated with a primitive trigeminal artery variant: case report. Neurosurgery 52:1217–1220

    Article  PubMed  Google Scholar 

  117. Tann E-C, Takagi T, Nagai H (1991) Intracranial carotid artery occlusion with telangiectasia (Moyamoya disease) associated with persistent primitive trigeminal artery—case report. Neurol Med Chir (Tokyo) 31:800–803

    Article  Google Scholar 

  118. Tanohata K, Maehara T, Noda M, Katoh H (1987) Internal carotid–cerebellar artery anastomosis: so-called persistent trigeminal artery variant (Images). http://ir.library.osaka-u.ac.jp/metadb/up/LIBLSK001/JJRS-47-9-1119-1126.pdf

  119. Teal JS, Rumbaugh CL, Bergeron RT, Scanlan RL, Segall HD (1972) Persistent carotid–superior cerebellar artery anastomosis: a variant of persistent trigeminal artery. Radiology 103:335–341

    PubMed  CAS  Google Scholar 

  120. Temizöz O, Genchellac H, Ünlü E, Çağlı B, Özdemir H, Demir MK (2010) Digital subtraction angiography of a persistent trigeminal artery variant. Diagn Interv Radiol (Turkish) 16:245–247

    Google Scholar 

  121. Terlecki M, Szopinski P, Huba M (2007) Persistent trigeminal artery—CTA findings. http://www.eurorad.org/case.php?id=6254

  122. Tomsick TA, Lukin RR, Chambers AA (1979) Persistent trigeminal artery: unusual associated abnormalities. Neuroradiology 17:253–257

    Article  PubMed  CAS  Google Scholar 

  123. Tortori-Donati P, Fondelli MP, Rossi A, Bava GL (1999) Intracranial contrast-enhancing masses in infants with capillary haemangioma of the head and neck: intracranial capillary haemangioma? Neuroradiology 41:369–375

    Article  PubMed  CAS  Google Scholar 

  124. Tsuboi K, Shibuya F, Yamada T, Nose T (1992) Giant aneurysm at the junction of the left internal carotid and persistent primitive trigeminal arteries—case report. Neurol Med Chir (Tokyo) 32:778–781

    Article  CAS  Google Scholar 

  125. Tubbs RS, Shoja MM, Salter EG, Oakes WJ (2007) Cadaveric findings of persistent trigeminal arteries. Clin Anat 20:367–370

    Article  PubMed  Google Scholar 

  126. Uchino A, Sawada A, Takase Y, Kudo S (2003) MR angiography of anomalous branches of the internal carotid artery. AJR 181:1409–1414

    PubMed  Google Scholar 

  127. Uzawa A, Aotsuka A, Terano T (2009) Cerebellar haemorrhage associated with persistent primitive trigeminal artery. J Clin Neurosci 16:152–154

    Article  PubMed  Google Scholar 

  128. Valença MM, Martins C, Andrade-Valença LPA (2008) Trigeminal neuralgia associated with persistent primitive trigeminal artery. Migrâneas cefaléias (Brasil) 11:30–32

    Google Scholar 

  129. Varghese SPJ (2007) Persistent trigeminal artery and associated vascular variations. Austral Radiol 51:B31–B33

    Article  Google Scholar 

  130. Vasović L. Morfološke karakteristike arterijskog prstena mozga kod različitog porekla kičmenih arterija. Doctoral thesis, Medical Faculty, Niš (in Serbian)

  131. Vasović L, Đorđević Z, Stefanović N, Pavlović S, Bakić V, Antić S (1990) Rare anomalies of the brain arteries. Persistence of the a. trigemini. Acta Med Medianae 1:91–96 (in Serbian)

    Google Scholar 

  132. Vasović L, Arsić S, Vlajković S, Jovanović I, Jovanović P, Ugrenović S, Anđelković Z (2010) Otic artery: a review of normal and pathological features. Med Sci Monit 16:RA101–RA109

    PubMed  Google Scholar 

  133. Vasović L, Milenković Z, Jovanović I, Čukuranović R, Jovanović P, Stefanović I (2008) Hypoglossal artery: a review of normal and pathological features. Neurosurg Rev 31:385–396

    Article  PubMed  Google Scholar 

  134. Vasović L, Mojsilović M, Anđelković Z, Jovanović I, Arsić S, Vlajković S, Milenković Z (2009) Proatlantal intersegmental artery: a review of normal and pathological features. Childs Nerv Syst 25:411–421

    Article  PubMed  Google Scholar 

  135. Waller FT, Simons RL, Kerber C, Kiesel IO, Tanabe CT (1977) Trigeminal artery and microemboli to the brain stem: report of two cases. J Neurosurg 46:104–106

    Article  PubMed  CAS  Google Scholar 

  136. Willinsky R, Lasjaunis P, Berenstein A (1987) Intracavernous branches of the internal carotid artery (ICA). Comprehensive review of their variations. Surg Radiol Anat 9:201–215

    Article  PubMed  CAS  Google Scholar 

  137. Wise BL, Palubinskas AJ (1964) Persistent trigeminal artery (carotid–basilar anastomosis). J Neurosurg 21:199–206

    Article  PubMed  CAS  Google Scholar 

  138. Wismer GL (1989) Circle of Willis variant analogous to fetal type primitive trigeminal artery. Neuroradiology 31:366–368

    Article  PubMed  CAS  Google Scholar 

  139. Yamada Y, Kondo A, Tanabe H (2006) Trigeminal neuralgia associated with an anomalous artery originating from the persistent primitive trigeminal artery—case report. Neurol Med Chir (Tokyo) 46:194–197

    Article  Google Scholar 

  140. Yang X, Mu S, Srivastava T, Wu Z (2007) Treatment of traumatic trigeminal–cavernous fistula by coil embolization and compression of carotid artery. Neurol India 55:396–398

    Article  PubMed  Google Scholar 

  141. Zhang C, Xie X, Yang Z, Wang C, You C, Mao B, He M, Sun H (2009) Giant cavernous aneurysm associated with a persistent trigeminal artery and persistent otic artery. Korean J Radiol 10:519–522

    Article  PubMed  Google Scholar 

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Acknowledgment

This work was supported by Ministry of Science and Technological Development of Republic of Serbia (contract grant number: 175092).

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Authors and Affiliations

  1. Department of Anatomy, Faculty of Medicine, University of Niš, Blvd. Dr Zoran Đinđić” 81, 18000, Niš, Serbia

    Ljiljana Vasović, Ivan Jovanović, Slađana Ugrenović, Slobodan Vlajković & Vesna Stojanović

  2. Clinique of Ophthalmology, Faculty of Medicine, University of Niš, Blvd. Dr Zoran Đinđić” 81, 18000, Niš, Serbia

    Predrag Jovanović

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  1. Ljiljana Vasović
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  2. Ivan Jovanović
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Correspondence to Ljiljana Vasović.

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Vasović, L., Jovanović, I., Ugrenović, S. et al. Trigeminal artery: a review of normal and pathological features. Childs Nerv Syst 28, 33–46 (2012). https://doi.org/10.1007/s00381-011-1622-7

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