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Rationale Antibiotikatherapie in der Augenheilkunde

Rational antibiotic therapy in ophthalmology

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Zusammenfassung

Bakterielle Infektionen können alle Strukturen des Auges betreffen. Infektionen der Oberflächen lassen sich in den meisten Fällen mit topischer Antibiotikagabe behandeln. Bei intraokularen Infektionen ist eine Kombination aus intraokularer und systemischer Antibiotikagabe erforderlich. Aus der Lokalisation, der Schwere der Infektion, dem erwarteten Keimspektrum und den möglichen Konsequenzen der Infektion ergeben sich sinnvolle Therapieempfehlungen. Unter dem Aspekt der Selektion multiresistenter Erreger sollte auch ein Einsatz von Antibiotika zur unbegründeten, vermeintlichen Prophylaxe oder bei nichtbakteriellen Infektionen vermieden werden.

Abstract

Bacterial infections can affect all structures of the eye. In most cases, infections of the ocular surface are treatable with topical antibiotics, whereas intraocular infections need a combined treatment with intraocular and systemic antibiotics. Localisation, severity, expected microorganisms, and possible consequences of the infection lead to the appropriate therapy. Unwarranted use of antibiotic substances for prophylaxis or treatment of nonbacterial infection should be avoided, especially because of possible selection of multiresistant microorganisms.

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Authors and Affiliations

  1. Universitäts-Augenklinik Magdeburg, Leipziger Straße 44, 39120, Magdeburg, Deutschland

    W. Behrens-Baumann

  2. Institut für Umweltmedizin und Krankenhaushygiene, Universitäts-Klinikum Freiburg, Freiburg, Deutschland

    U. Frank

  3. Universitäts-Augenklinik Freiburg, Freiburg, Deutschland

    T. Neß

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  1. W. Behrens-Baumann
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  2. U. Frank
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  3. T. Neß
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Correspondence to W. Behrens-Baumann.

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Behrens-Baumann, W., Frank, U. & Neß, T. Rationale Antibiotikatherapie in der Augenheilkunde. Ophthalmologe 107, 323–327 (2010). https://doi.org/10.1007/s00347-009-2077-z

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