Abstract
Purpose
The impact of transarterial embolization (TAE) and nephrectomy on acute kidney injury (AKI) in blunt renal trauma patients remains unclear, and we used the National Trauma Data Bank (NTDB) to investigate this issue.
Methods
Adult patients from the NTDB between 2007 and 2015 who survived traumatic events with blunt injuries were eligible for inclusion. The exclusion criteria were those without outcome information, who required dialysis, or with chronic renal failure prior to the traumatic injury. Patients sustaining hepatic, splenic, or pelvic fractures or who had bilateral nephrectomy were also excluded. The patients were divided into three treatment groups, including conservative treatment, TAE, and nephrectomy. Two statistical models, logistic regression (LR) and inverse probability treatment weighting (IPTW), were used to clarify the AKI predictors.
Results
The study included 10,096 patients. There were 9697 (96.0%), 202 (2.0%) and 197 (2.0%) patients in the conservative, TAE and nephrectomy groups, respectively. Nephrectomy was a statistically significant predictor of AKI in blunt renal trauma patients in the standard LR (odds ratio [OR], 4.58; 95% confidence interval [CI] 1.92–10.38; p < 0.001) and IPTW (OR, 5.16; 95% CI 1.07–24.85; p = 0.023) models. In addition, TAE was not a risk factor for AKI in blunt renal trauma patients (p > 0.05 in all models).
Conclusion
AKI is less likely affect patients with blunt renal trauma with TAE than those with nephrectomy. Nephrectomy is a risk factor for AKI in blunt renal trauma patients. TAE should be considered first when blunt renal trauma patients need a hemostatic procedure.
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C-PH: project development, data management, data analysis, and manuscript writing. C-TC: project development and data analysis. J-FH: project development, data analysis, and manuscript editing. C-YF: project development, data analysis, and manuscript editing. FB: project development and data analysis. MB: project development and data analysis. JM: project development and data analysis. SP: project development and data analysis. FB: project development and data analysis.
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Hsu, CP., Cheng, CT., Huang, JF. et al. The effect of transarterial embolization versus nephrectomy on acute kidney injury in blunt renal trauma patients. World J Urol 40, 1859–1865 (2022). https://doi.org/10.1007/s00345-022-04049-5
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DOI: https://doi.org/10.1007/s00345-022-04049-5