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Efficacy and safety of skeletonized mesh implants for advanced pelvic organ prolapse: 12-month follow-up

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World Journal of Urology Aims and scope Submit manuscript

A Letter to the Editor to this article was published on 25 May 2016

Abstract

Objective

To evaluate the efficacy and safety of skeletonized mesh implants for advanced pelvic organ prolapse (POP).

Methods

Women with advances POP underwent repair of stage III or greater anterior or posterior and apical compartment prolapse using skeletonized mesh implants (Seratom PA MR MN® system—SERAG-WIESSNER, Naila, Germany). Anatomical outcomes were assessed using pelvic organ prolapse quantification staging and functional outcomes were self-reported by the patients at 6 weeks, 6 and 12 months. Anatomical and functional cure rates, post-operative pain and dyspareunia as well as intra and post-operative complications were reported. Success was defined as a composite of no bulge symptoms and no prolapse beyond the hymenal ring.

Results

At 12 months, data were available for 103 of the 105 patients originally recruited. Intra-operative complications included 2 (2 %) cases of cystotomy that were corrected vaginally. The immediate post-operative complications included 1 patient (1 %) with UTI, 4 (3.9 %) cases of self-resolved hematomas, and 6 (5.8 %) cases of bladder outlet obstruction. At 12 months, a high success rate and low complication rate was noted. Recurrence of prolapse was reported by 7 (6.6 %) patients. However, only 4 (3.8 %) underwent a repeat procedure. Two patient developed de novo SUI, and 6 (5.7 %) developed dyspareunia. No cases of mesh erosion/extrusion were noted.

Conclusion

The present study showed excellent anatomical and quality of life results in patients with advanced POP treated with a skeletonized and reduced mesh system. No mesh exposure was recorded within the first year after surgery.

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Author contributions

Adi Y. Weintraub was involved in data analysis and manuscript writing/editing; Menahem Neuman was involved in protocol/project development, data collection and manuscript writing/editing; Yonatan Reuven was involved in data analysis and manuscript writing/editing; Joerg Neymeyer was involved in manuscript editing; and Naama Marcus-Braun was involved in protocol/project development, data analysis and manuscript writing/editing.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel

    Adi Y. Weintraub

  2. Urogynecology, Department of Obstetrics and Gynecology, Galilee Medical Center, Affiliated with Faculty of Medicine in the Galilee, Bar Ilan University, Safed, Israel

    Menahem Neuman

  3. Assuta Medical Centers, Tel Aviv, Rishon LeZion, Israel

    Menahem Neuman

  4. Division of Community Health, Siaal Research Center for Family Medicine and Primary Care, Faculty of Health Science, Ben-Gurion University of the Negev, Beer Sheva, Israel

    Yonatan Reuven

  5. Department of Urology, Charitè University, Berlin, Germany

    Joerg Neymeyer

  6. Department of Obstetrics and Gynecology, Ziv Medical Center, Affiliated with Faculty of Medicine in the Galilee, Bar Ilan University, Safed, Israel

    Naama Marcus-Braun

Authors
  1. Adi Y. Weintraub
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Corresponding author

Correspondence to Adi Y. Weintraub.

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Conflict of interest

Authors AYW, YR and NMB have nothing to declare, MN receives royalties from SERAG-WIESSNER, and JN serves as a consultant for SERAG-WIESSNER.

Ethical approval

The study was approved by the local institutional ethics committee in accordance with the principles of the Declaration of Helsinki.

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Weintraub, A.Y., Neuman, M., Reuven, Y. et al. Efficacy and safety of skeletonized mesh implants for advanced pelvic organ prolapse: 12-month follow-up. World J Urol 34, 1491–1498 (2016). https://doi.org/10.1007/s00345-016-1792-8

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  • DOI: https://doi.org/10.1007/s00345-016-1792-8

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