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Study of an anisotropic ferrimagnetic bioactive glass ceramic for cancer treatment

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Abstract

For the hyperthermia therapy of cancer, ferrimagnetic glass ceramics are a potential candidate. Ferrimagnetic zinc-ferrite-containing bioactive glass ceramics were prepared by quenching the glass ceramics from sintering temperature. Then the samples were heated to 600°C and cooled in an aligning magnetic field of 1 Tesla to cause anisotropy. The magnetically aligned samples were compared with non-aligned samples. Vibrating sample magnetometry measurements at 10 kOe showed that the magnetic properties were enhanced by the aligning magnetic field and it led to an enhancement of the magnetic heat generation under a magnetic induction furnace operating at 500 Oe and 400 kHz for 2 min. Data showed that the maximum specific power loss and temperature increase after 2 min were 31.5 W/g and 45°C, respectively, for the aligned sample of maximum zinc-ferrite crystalline content. The glass ceramics were immersed in simulated body fluid for 3 weeks. X-ray diffraction and Fourier transform infrared and atomic absorption spectroscopy results indicated the growth of precipitated hydroxyapatite, suggesting that the ferrimagnetic glass ceramics were bioactive and could bond to living tissues in physiological environment.

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References

  1. O. Bretcanu, S. Spriano, C.B. Vitale, E. Verne, J. Mater. Sci. 41, 1029 (2006)

    Article  ADS  Google Scholar 

  2. G.H. Nussbaum, Physical Aspects of Hyperthermia (American Institute of Physics, New York, 1982)

    Google Scholar 

  3. Y. Ebisawa, F. Miyaji, T. Kokubo, K. Ohura, T. Nakamura, Biomaterials 18, 1277 (1997)

    Article  Google Scholar 

  4. M. Kawashita, Y. Iwahashi, T. Kokubo, T. Yao, S. Hamada, T. Shinjo, J. Ceram. Soc. Jpn. 112, 373 (2004)

    Article  Google Scholar 

  5. O. Bretcanu, E. Verne, M. Coisson, P. Tiberto, P. Allia, J. Magn. Magn. Mater. 305, 529 (2006)

    Article  ADS  Google Scholar 

  6. C.S. Hsi, H.Z. Cheng, H.J. Hsu, Y.S. Chen, M.C. Wang, J. Eur. Ceram. Soc. 27, 3171 (2007)

    Article  Google Scholar 

  7. S.A.M. Abdel-Hameed, M.M. Hessien, M.A. Azooz, Ceram. Int. 35(4), 1539 (2009)

    Article  Google Scholar 

  8. S. Murakami, T. Hosono, B. Jeyadevan, M. Kamitakahara, K. Ioku, J. Ceram. Soc. Jpn. 116, 950 (2008)

    Article  Google Scholar 

  9. R.K. Singh, G.P. Kothiyal, A. Srinivasan, J. Magn. Magn. Mater. 320, 1352 (2007)

    Article  ADS  Google Scholar 

  10. S.A. Shah, M.U. Hashmi, S. Alam, A. Shamim, J. Magn. Magn. Mater. 322, 375 (2010)

    Article  ADS  Google Scholar 

  11. Th. Leventouri, A.C. Kis, J.R. Thompson, I.M. Anderson, Biomaterials 26, 4925 (2005)

    Article  Google Scholar 

  12. K. Singh, D. Bahadur, J. Mater. Sci. Mater. Med. 10, 481 (1999)

    Google Scholar 

  13. S.A. Shah, M.U. Hashmi, A. Shamim, S. Alam, J. Mater. Sci. Technol. (2010, accepted)

  14. O. Bretcanu, S. Spriano, E. Verne, M. Coisson, P. Tiberto, P. Allia, Acta Biomater. 1, 423 (2005)

    Article  Google Scholar 

  15. V. Sepelak, K.D. Becker, Mater. Sci. Eng. A 375–377, 861 (2004)

    Google Scholar 

  16. H.S.C. O’Neill, H. Annersten, D. Virgo, Am. Miner. 77, 725 (1992)

    Google Scholar 

  17. M. Atif, S.K. Hasnain, M. Nadeem, Solid State Commun. 138, 416 (2006)

    Article  ADS  Google Scholar 

  18. R.V. Upadhyay, Pramana 49, 309 (1997)

    Article  ADS  Google Scholar 

  19. R.W. Gao, J.C. Zhang, D.H. Zhang, Y.Y. Dai, X.H. Meng, Z.M. Wang, Y.J. Zhang, H.Q. Liu, J. Magn. Magn. Mater. 191, 97 (1999)

    Article  ADS  Google Scholar 

  20. Y. Sun, R.W. Gao, G.B. Han, G. Bai, T. Liu, B. Wang, J. Magn. Magn. Mater. 299, 82 (2006)

    Article  ADS  Google Scholar 

  21. C.G. Pantano, A.E. Clark, L.L. Hench, J. Am. Ceram. Soc. 57, 412 (1974)

    Article  Google Scholar 

  22. L.L. Hench, J. Am. Ceram. Soc. 81, 1705 (1998)

    Google Scholar 

  23. O. Peitl, E.D. Zanotto, L.L. Hench, J. Non-Cryst. Solids 292, 116 (2001)

    Article  Google Scholar 

  24. J.M. Oliveira, R.N. Correia, M.H. Fernandes, Biomaterials 23, 371 (2002)

    Article  Google Scholar 

  25. D.M. Souza, A.L. Andrade, J.D. Fabris, P. Valério, A.M. Góes, M.F. Leite, R.Z. Domingues, J. Non-Cryst. Solids 354, 4894 (2008)

    Article  ADS  Google Scholar 

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Authors and Affiliations

  1. Biomaterials Lab, Department of Physics, GC University, Lahore, Pakistan

    Saqlain A. Shah, M. U. Hashmi & A. Shamim

  2. Pakistan Council of Scientific and Industrial Research, Lahore, Pakistan

    S. Alam

Authors
  1. Saqlain A. Shah
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  2. M. U. Hashmi
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  3. A. Shamim
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  4. S. Alam
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Correspondence to Saqlain A. Shah.

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Shah, S.A., Hashmi, M.U., Shamim, A. et al. Study of an anisotropic ferrimagnetic bioactive glass ceramic for cancer treatment. Appl. Phys. A 100, 273–280 (2010). https://doi.org/10.1007/s00339-010-5801-2

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  • DOI: https://doi.org/10.1007/s00339-010-5801-2

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