Skip to main content
SpringerLink
Log in

Mapping of rat Chromosome 2 markers generated from chromosome-sorted DNA

  • Published:
Mammalian Genome Aims and scope Submit manuscript

Abstract.

A quantitative trait locus (QTL) for blood pressure has recently been mapped to a region of roughly 30 cM on rat Chromosome (Chr) 2 by linkage and by the use of congenic strains. For further fine mapping of the QTL, however, closely linked chromosome markers residing in this 30-cM region are required. In the current work, 36 new markers were generated by screening rat Chr 2-sorted DNA libraries and subsequently mapped using five F2 populations. Combining new and existing markers, the marker density for the 30-cM region approaches, on average, one marker per 1.1 cM.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Department of Physiology and Molecular Medicine, Medical College of Ohio, 3000 Arlington Avenue, P.O. Box 10008, Toledo, Ohio 43699-0008, USA, , , , , , US

    Alan Y. Deng & John P. Rapp

  2. Department of Medicine, Medical College of Ohio, Toledo, Ohio 43699, USA, , , , , , US

    Clara M. Jackson

  3. Laboratory of Health Effects Research, National Institutes of Public Health and Environmental Protection, Bilthoven 3720 RA, The Netherlands, , , , , , NL

    Barbara Hoebee

Authors
  1. Alan Y. Deng
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Clara M. Jackson
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Barbara Hoebee
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. John P. Rapp
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Received: 11 April 1997 / Accepted: 12 May 1997

Rights and permissions

Reprints and permissions

About this article

Cite this article

Deng, A., Jackson, C., Hoebee, B. et al. Mapping of rat Chromosome 2 markers generated from chromosome-sorted DNA. 8, 731–735 (1997). https://doi.org/10.1007/s003359900555

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s003359900555

Keywords

Search

Navigation