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Measurement of cardiac ventricular volumes using multidetector row computed tomography: comparison of two- and three-dimensional methods

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Abstract

This study compared a three-dimensional volumetric threshold-based method to a two-dimensional Simpson’s rule based short-axis multiplanar method for measuring right (RV) and left ventricular (LV) volumes, stroke volumes, and ejection fraction using electrocardiography-gated multidetector computed tomography (MDCT) data sets. End-diastolic volume (EDV) and end-systolic volume (ESV) of RV and LV were measured independently and blindly by two observers from contrast-enhanced MDCT images using commercial software in 18 patients. For RV and LV the three-dimensionally calculated EDV and ESV values were smaller than those provided by two-dimensional short axis (10%, 5%, 15% and 26% differences respectively). Agreement between the two methods was found for LV (EDV/ESV: r=0.974/0.910, ICC=0.905/0.890) but not for RV (r=0.882/0.930, ICC=0.663/0.544). Measurement errors were significant only for EDV of LV using the two-dimensional method. Similar reproducibility was found for LV measurements, but the three-dimensional method provided greater reproducibility for RV measurements than the two-dimensional. The threshold value supported three-dimensional method provides reproducible cardiac ventricular volume measurements, comparable to those obtained using the short-axis Simpson based method.

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References

  1. Dodge HT, Sandler H, Ballew DW, Lord JD (1960) The use of biplane angiocardigraphy for the measurement of left ventricular volume in man. Am Heart J 60:762–776

    Article  PubMed  CAS  Google Scholar 

  2. Greenberg SB, Sandhu SK (1999) Ventricular function. Radiol Clin North Am 37:341–359

    Article  PubMed  CAS  Google Scholar 

  3. Moon JC, Lorenz CH, Francis JM, Smith GC, Pennell DJ (2002) Breath-hold FLASH and FISP cardiovascular MR imaging: left ventricular volume differences and reproducibility. Radiology 223:789–797

    Article  PubMed  Google Scholar 

  4. Juergens KU, Grude M, Maintz D, Fallenberg EM, Wichter T, Heindel W, Fischbach R (2004) Multi-detector row CT of left ventricular function with dedicated analysis software versus MR imaging: initial experience. Radiology 230:403–410

    Article  PubMed  Google Scholar 

  5. Grude M, Juergens KU, Wichter T, Paul M, Fallenberg EM, Muller JG, Heindel W, Breithardt G, Fischbach R (2003) Evaluation of global left ventricular myocardial function with electrocardiogram-gated multidetector computed tomography: comparison with magnetic resonance imaging. Invest Radiol 38:653–661

    Article  PubMed  Google Scholar 

  6. Halliburton SS, Petersilka M, Schvartzman PR, Obuchowski N, White RD (2003) Evaluation of left ventricular dysfunction using multiphasic reconstructions of coronary multi-slice computed tomography data in patients with chronic ischemic heart disease: validation against cine magnetic resonance imaging. Int J Cardiovasc Imaging 19:73–83

    Article  PubMed  Google Scholar 

  7. Hosoi S, Mochizuki T, Miyagawa M, Shen Y, Murase K, Ikezoe J (2003) Assessment of left ventricular volumes using multi-detector row computed tomography (MDCT): phantom and human studies. Radiat Med 21:62–67

    PubMed  Google Scholar 

  8. Mahnken AH, Spuentrup E, Niethammer M, Buecker A, Boese J, Wildberger JE, Flohr T, Sinha AM, Krombach GA, Gunther RW (2003) Quantitative and qualitative assessment of left ventricular volume with ECG-gated multislice spiral CT: value of different image reconstruction algorithms in comparison to MRI. Acta Radiol 44:604–611

    Article  PubMed  CAS  Google Scholar 

  9. Schlosser T, Pagonidis K, Herborn CU, Hunold P, Waltering KU, Lauenstein TC, Barkhausen J (2005) Assessment of left ventricular parameters using 16-MDCT and new software for endocardial and epicardial border delineation. AJR Am J Roentgenol 184:765–773

    PubMed  Google Scholar 

  10. Mochizuki T, Murase K, Higashino H, Koyama Y, Doi M, Miyagawa M, Nakata S, Shimizu K, Ikezoe J (2000) Two- and three-dimensional CT ventriculography: a new application of helical CT. AJR Am J Roentgenol 174:203–208

    PubMed  CAS  Google Scholar 

  11. Heuschmid M, Kuttner A, Schroder S, Trebar B, Burgstahler C, Mahnken A, Niethammer M, Trabold T, Kopp AF, Claussen CD (2003) Left ventricular functional parameters using ECG-gated multidetector spiral CT in comparison with invasive ventriculography. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 175:1349–1354

    Article  PubMed  CAS  Google Scholar 

  12. Kim TH, Ryu YH, Hur J, Kim SJ, Kim HS, Choi BW, Kim Y, Kim HJ (2005) Evaluation of right ventricular volume and mass using retrospective ECG-gated cardiac multidetector computed tomography: comparison with first-pass radionuclide angiography. Eur Radiol 15:1987–1993

    Article  PubMed  Google Scholar 

  13. Koch K, Oellig F, Oberholzer K, Bender P, Kunz P, Mildenberger P, Hake U, Kreitner KF, Thelen M (2005) Assessment of right ventricular function by 16-detector-row CT: comparison with magnetic resonance imaging. Eur Radiol 15:312–318

    Article  PubMed  CAS  Google Scholar 

  14. Coche E, Vlassenbroek A, Roelants V, D’Hoore W, Verschuren F, Goncette L, Maldague B (2005) Evaluation of biventricular ejection fraction with ECG-gated 16-slice CT: preliminary findings in acute pulmonary embolism in comparison with radionuclide ventriculography. Eur Radiol 15:1432–1440

    Article  PubMed  Google Scholar 

  15. Ehrhard K, Oberholzer K, Gast K, Mildenberger P, Kreitner KF, Thelen M (2002) Multi-slice CT (MSCT) in cardiac function imaging: threshold-value-supported 3D volume reconstructions to determine the left ventricular ejection fraction in comparison to MRI. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 174:1566–1569

    Article  PubMed  CAS  Google Scholar 

  16. Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet I:307–310

    Google Scholar 

  17. Nieman K, Pattynama PM, Rensing BJ, Van Geuns RJ, De Feyter PJ (2003) Evaluation of patients after coronary artery bypass surgery: CT angiographic assessment of grafts and coronary arteries. Radiology 229:749–756

    Article  PubMed  Google Scholar 

  18. Paul JF, Dambrin G, Caussin C, Lancelin B, Angel C (2003) Sixteen-slice computed tomography after acute myocardial infarction: from perfusion defect to the culprit lesion. Circulation 108:373–374

    Article  PubMed  Google Scholar 

  19. Willmann JK, Weishaupt D, Lachat M, Kobza R, Roos JE, Seifert B, Luscher TF, Marincek B, Hilfiker PR (2002) Electrocardiographically gated multi-detector row CT for assessment of valvular morphology and calcification in aortic stenosis. Radiology 225:120–128

    Article  PubMed  Google Scholar 

  20. Alfakih K, Plein S, Bloomer T, Jones T, Ridgway J, Sivananthan M (2003) Comparison of right ventricular volume measurements between axial and short axis orientation using steady-state free precession magnetic resonance imaging. J Magn Reson Imaging 18:25–32

    Article  PubMed  Google Scholar 

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Montaudon, M., Laffon, E., Berger, P. et al. Measurement of cardiac ventricular volumes using multidetector row computed tomography: comparison of two- and three-dimensional methods. Eur Radiol 16, 2341–2349 (2006). https://doi.org/10.1007/s00330-006-0222-5

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  • DOI: https://doi.org/10.1007/s00330-006-0222-5

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