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Assessment of right ventricular function by 16-detector-row CT: comparison with magnetic resonance imaging

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Abstract

The purpose of this study was to determine right ventricular (RV) function from 16-detector-row CT by using two different software tools in comparison with MRI. Nineteen patients underwent cardiac CT. (1) With semiautomated contour detection software end-diastolic and end-systolic RV volumes were determined from short-axis CT reformations (MPR) created at every 10% of the RR-interval. (2) End-systolic and end-diastolic axial images were transformed to 3D to determine the volumes by using a threshold-supported reconstruction algorithm. Steady-state free-precession cine-MRI of the heart was done in short-axis orientation. RV function could not be analyzed in one patient because of sternal wire artifacts in MRI. Mean end-diastolic (155.4±54.6 ml) and end-systolic (79.1±37.0 ml) RV volumes determined with MPR correlated well with MRI [151.9±53.7 ml (r=0.98) and 75.0±36.0 ml (r=0.96), respectively (P<0.001)]. RV stroke volume (76.2±20.2 ml for MPR-CT, 76.9±20.7 ml for MRI, r=0.93) showed a good correlation and RV ejection fraction (50.8±8.4% for MPR-CT, 51.9±7.4% for MRI, r=0.74) only a moderate one. Threshold supported 3D reconstructions revealed insufficient correlations with MRI (r=0.31–0.59). MPR-based semiautomated analysis of cardiac 16 detector-row CT allows for RV functional analysis. The results correlate well with MRI findings. Threshold value-supported 3D reconstructions did not show satisfying results because of inhomogeneities of RV contrast enhancement.

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Authors and Affiliations

  1. Department of Radiology, Johannes Gutenberg-University Mainz, 55131, Mainz, Germany

    K. Koch, F. Oellig, K. Oberholzer, P. Bender, P. Kunz, P. Mildenberger, K.-F. Kreitner & M. Thelen

  2. Department of Cardiothoracic and Vascular Surgery, Johannes Gutenberg-University Mainz, 55131, Mainz, Germany

    U. Hake

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  1. K. Koch
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  2. F. Oellig
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  3. K. Oberholzer
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  4. P. Bender
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  5. P. Kunz
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  6. P. Mildenberger
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  7. U. Hake
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  8. K.-F. Kreitner
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  9. M. Thelen
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Correspondence to K. Koch.

Additional information

This paper contains parts of the doctoral thesis of Cand. Med. P. Bender.

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Koch, K., Oellig, F., Oberholzer, K. et al. Assessment of right ventricular function by 16-detector-row CT: comparison with magnetic resonance imaging. Eur Radiol 15, 312–318 (2005). https://doi.org/10.1007/s00330-004-2543-6

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  • DOI: https://doi.org/10.1007/s00330-004-2543-6

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