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Validity and reliability of the Persian version of Behçet’s disease quality-of-life (BD-QoL) questionnaire: a cross-cultural adaptation

  • Original Article - Validation Studies
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Abstract

The Leeds Behçet’s disease quality-of-life (BD-QoL) questionnaire is a specific and valid measure which is applied in English-speaking patients. We conducted Persian adaptation of BD-QoL questionnaire. Between June and December 2012, 220 Iranian patients fulfilling International Study Group criteria for the diagnosis of BD attending the rheumatology clinics at Tehran University of Medical Sciences were enrolled. Bilingual translators undertook the forward translation and cross-cultural adaptation of the BD-QoL questionnaire. Back-translation was conducted, and this version was sent to the designer of the questionnaire and revised accordingly. SF-36 health survey, Iranian Behçet’s disease dynamic activity measure (IBDDAM), and Behçet’s Disease Current Activity Form (BDCAF) were other administered measures. The Varimax rotation method with Kaiser normalization defined 5 factors with eigenvalues greater than 1.0. Studied cases were comprised of 118 males (53.6 %) and 102 females (46.4 %). Mean age of the patients was 38.3 ± 11.3 years (range 16–73). The mean BD-QoL score was 10.3 ± 8.8. Test–retest reliability was high, and two time points were significantly correlated (Spearman’s correlation coefficient of 0.75–0.84). Cronbach’s α coefficient of 0.949 demonstrated the excellent internal consistency. These factors cumulatively explained 58.74 % of total variance. The ratio of first to second eigenvalue was 7.08, which underlined the undimensionality. The results revealed adapted BD-QoL scores had significant correlation with IBDDAM (correlation coefficient = 0.19, P value = 0.005) and BDCAF (correlation coefficient = 0.21, P value = 0.002). Conversely, no significant correlation between BD-QoL and SF-36 results was detected (P value = 0.078). The Persian version of BD-QoL was shown to be unidimensional, highly reliable, and adequate construct validity.

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References

  1. Davatchi F, Shahram F, Chams-Davatchi C, Shams H, Nadji A, Akhlaghi M et al (2010) Behcet’s disease in Iran: analysis of 6500 cases. Int J Rheum Dis. 13(4):367–373

    Article  PubMed  Google Scholar 

  2. Kaneko F, Nakamura K, Sato M, Tojo M, Zheng X, Zhang JZ (2003) Epidemiology of Behcet’s disease in Asian countries and Japan. Adv Exp Med Biol 528:25–29

    Article  PubMed  Google Scholar 

  3. Zouboulis CC (1999) Epidemiology of Adamantiades-Behcet’s disease. Ann Med Intern (Paris) 150(6):488–498

    CAS  Google Scholar 

  4. Davatchi F, Shahram F, Chams-Davatchi C, Shams H, Nadji A, Akhlaghi M et al (2010) Behcet’s disease: from east to west. Clin Rheumatol 29(8):823–833

    Article  PubMed  Google Scholar 

  5. Kaneko F, Togashi A, Saito S, Sakuma H, Oyama N, Nakamura K et al (2011) Behcet’s disease (Adamantiades-Behcet’s disease). Clin Dev Immunol 2011:681956

    Article  PubMed Central  PubMed  Google Scholar 

  6. Mumcu G, Inanc N, Ergun T, Ikiz K, Gunes M, Islek U et al (2006) Oral health related quality of life is affected by disease activity in Behcet’s disease. Oral Dis 12(2):145–151

    Article  CAS  PubMed  Google Scholar 

  7. Gilworth G, Chamberlain MA, Bhakta B, Haskard D, Silman A, Tennant A (2004) Development of the BD-QoL: a quality of life measure specific to Behcet’s disease. J Rheumatol 31(5):931–937

    PubMed  Google Scholar 

  8. Gur A, Sarac AJ, Burkan YK, Nas K, Cevik R (2006) Arthropathy, quality of life, depression, and anxiety in Behcet’s disease: relationship between arthritis and these factors. Clin Rheumatol 25(4):524–531

    Article  PubMed  Google Scholar 

  9. Tanriverdi N, Taskintuna Duru C, Ozdal P, Ortac S, Firat E (2003) Health-related quality of life in Behcet patients with ocular involvement. Jpn J Ophthalmol 47(1):85–92

    Article  PubMed  Google Scholar 

  10. Kievit W, Fransen J, de Waal Malefijt MC, den Broeder AA, van Riel PL (2013) Treatment changes and improved outcomes in RA: an overview of a large inception cohort from 1989 to 2009. Rheumatology (Oxford) 52(8):1500–1508

    Article  Google Scholar 

  11. Blackford S, Finlay AY, Roberts DL (1997) Quality of life in Behcet’s syndrome: 335 patients surveyed. Br J Dermatol 136(2):293

    Article  CAS  PubMed  Google Scholar 

  12. Bodur H, Borman P, Ozdemir Y, Atan C, Kural G (2006) Quality of life and life satisfaction in patients with Behcet’s disease: relationship with disease activity. Clin Rheumatol 25(3):329–333

    Article  PubMed  Google Scholar 

  13. Moses Alder N, Fisher M, Yazici Y (2008) Behcet’s syndrome patients have high levels of functional disability, fatigue and pain as measured by a Multi-dimensional Health Assessment Questionnaire (MDHAQ). Clin Exp Rheumatol 26(4 Suppl 50):S110–S113

    CAS  PubMed  Google Scholar 

  14. Guyatt GH, Feeny DH, Patrick DL (1993) Measuring health-related quality of life. Ann Intern Med 118(8):622–629

    Article  CAS  PubMed  Google Scholar 

  15. Ertam I, Kitapcioglu G, Aksu K, Keser G, Ozaksar A, Elbi H et al (2009) Quality of life and its relation with disease severity in Behcet’s disease. Clin Exp Rheumatol 27(2 Suppl 53):S18–S22

    CAS  PubMed  Google Scholar 

  16. Hirayama MS, Gobbi S, Gobbi LT, Stella F (2008) Quality of life (QoL) in relation to disease severity in Brazilian Parkinson’s patients as measured using the WHOQOL-BREF. Arch Gerontol Geriatr 46(2):147–160

    Article  PubMed  Google Scholar 

  17. Touma Z, Ghandour L, Sibai A, Puzantian H, Hamdan A, Hamdan O et al (2011) Cross-cultural adaptation and validation of Behcet’s disease quality of life questionnaire. BMC Med Res Methodol 11:52

    Article  PubMed Central  PubMed  Google Scholar 

  18. Yi SW, Kim JH, Lim KY, Bang D, Lee S, Lee ES (2008) The Behcet’s Disease Quality of Life: reliability and validity of the Korean version. Yonsei Med J 49(5):698–704

    Article  PubMed Central  PubMed  Google Scholar 

  19. (1990) Criteria for diagnosis of Behcet’s disease. International Study Group for Behcet’s Disease. Lancet 335(8697):1078–1080

  20. Ware JE Jr, Sherbourne CD (1992). The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 30(6):473–483

    Article  PubMed  Google Scholar 

  21. Shahram F, Khabbazi A, Nadji A, Ziaie N, Banihashemi AT, Davatchi F (2009) Comparison of existing disease activity indices in the follow-up of patients with Behcet’s disease. Mod Rheumatol 19(5):536–541

    Article  PubMed  Google Scholar 

  22. Jamshidi A, Shahram F, Akbarian M, Gharibdoost F, Nadji A, Chams C (2001) The accuracy of IBDDAM (Iran Behcet’s disease dynamic measure) in the treatment evaluation of Behcet’s disease. APLAR J Rheumatol 4:161–163

    Google Scholar 

  23. Bhakta BB, Brennan P, James TE, Chamberlain MA, Noble BA, Silman AJ (1999) Behcet’s disease: evaluation of a new instrument to measure clinical activity. Rheumatology (Oxford) 38(8):728–733

    Article  CAS  Google Scholar 

  24. Beaton DE, Bombardier C, Guillemin F, Ferraz MB (2000) Guidelines for the process of cross-cultural adaptation of self-report measures. Spine 25(24):3186–3191

    Article  CAS  PubMed  Google Scholar 

  25. Black R, Lester S, Dunstan E, Shahram F, Nadji A, Bayat N et al (2012) Fc-gamma receptor 3B copy number variation is not a risk factor for Behcet’s disease. Int J Rheumatol 2012:167096

    Article  PubMed Central  PubMed  Google Scholar 

  26. Strand V, Gladman D, Isenberg D, Petri M, Smolen J, Tugwell P (2000) Endpoints: consensus recommendations from OMERACT IV. Outcome measures in rheumatology. Lupus 9(5):322–327

    Article  CAS  PubMed  Google Scholar 

  27. Ertam I, Kitapcioglu G, Aksu K, Keser G, Ozaksar A, Elbi H et al (2009) Quality of life and its relation with disease severity in Behçet’s disease. Clin Exp Rheumatol 27(2):S18

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, North Kargar Avenue, Tehran, Iran

    Mahdi Vojdanian, Seyedeh Tahereh Faezi, Maryam Mattaji & Fereydoun Davatchi

  2. Leeds Institute Rheumatic and Musculoskeletal Medicine, St. James’s University Hospital, Leeds, UK

    Alan Tennant

  3. Department of Rehabilitation Medicine, Faculty of Medicine and Health, The University of Leeds, Leeds, UK

    Ann W. Morgan

  4. Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran

    Pedram Paragomi

  5. Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

    Mostafa Qorbani

Authors
  1. Mahdi Vojdanian
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  2. Seyedeh Tahereh Faezi
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  3. Alan Tennant
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  4. Ann W. Morgan
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  5. Pedram Paragomi
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  7. Maryam Mattaji
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  8. Fereydoun Davatchi
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Correspondence to Seyedeh Tahereh Faezi.

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Vojdanian, M., Faezi, S.T., Tennant, A. et al. Validity and reliability of the Persian version of Behçet’s disease quality-of-life (BD-QoL) questionnaire: a cross-cultural adaptation. Rheumatol Int 35, 677–684 (2015). https://doi.org/10.1007/s00296-014-3128-6

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  • DOI: https://doi.org/10.1007/s00296-014-3128-6

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