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Validity and reliability of a checklist for patients with Behçet’s disease based on the International Classification of Functioning, Disability and Health

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Abstract

In 2020, we reported the “BD-checklist 92” for patients with Behçet’s disease (BD) based on the International Classification of Functioning, Disability and Health. The purpose of the present study was to evaluate the validity and reliability of this checklist. Questionnaires using the “BD-checklist 92” and the 36-item Short Form Survey (SF-36) were sent to ten affiliated institutions. In total, 174 patients answered the questionnaire (response rate, 32.7%). Criterion validity was evaluated using the correlation coefficient between the number of problem categories extracted from the “BD-checklist 92” and the scores of the eight subscales and two components of the SF-36. Construct validity was assessed based on the number of problem categories extracted as an external criterion for the number of manifestations experienced and specific lesions. The comparison was performed using the Mann–Whitney U test. Cronbach’s alpha coefficient was used to evaluate reliability. The number of problem categories in the “Body functions and structures”, “Activities and participation”, and “Environmental factors” components correlated significantly with all dimensions of the SF-36 questionnaire (P < 0.05 each). Construct validity showed that the number of manifestations experienced in all components (P < 0.001 each) and specific lesions in “Body functions and structures” and “All categories” (P = 0.002 and 0.050, respectively) contributed to an increased number of problems associated with BD. Cronbach’s alpha coefficient for the “BD-checklist 92” was 0.926. This study confirmed the validity and reliability of the “BD-checklist 92”.

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Acknowledgements

This study was supported by JSPS KAKENHI Grant Number 16K04187. The authors would like to thank Associate Professor Y. Kirino from the Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine; Associate Professor H. Nagafuchi from the Departments of Rheumatology and Allergy, St. Marianna University School of Medicine; Clinical Associate Professor K. Namba from the Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University; Professor T. Sawada from the Department of Rheumatology, Tokyo Medical University; Clinical Associate Professor T. Tono from the Department of Rheumatology and Infectious Diseases, Kitasato University School of Medicine; Professor K. Nakamura from the Department of Dermatology, Saitama Medical University; Professor N. Kitaichi from the Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University; Visiting Professor S. Hirohata from the Division of Rheumatology and Allergy, Department of Internal Medicine, Teikyo University School of Medicine; and Health and Labour Sciences Research Grants (Research on Intractable Diseases) from the Ministry of Health, Labour and Welfare of Japan, for their support with respect to the mail survey.

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This study was supported by JSPS KAKENHI Grant Number 16K04187.

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Correspondence to Hideyo Tsutsui.

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Tsutsui, H., Kikuchi, H., Oguchi, H. et al. Validity and reliability of a checklist for patients with Behçet’s disease based on the International Classification of Functioning, Disability and Health. Rheumatol Int 42, 159–165 (2022). https://doi.org/10.1007/s00296-021-05001-3

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