Zusammenfassung
Eine Magenschleimhautheterotopie ist im Rektum ein äußerst seltener Befund. Es existieren 3 ätiopathogenetische Hypothesen, wobei man heute von einer Fehldifferenzierung entodermaler Stammzellen ausgeht. Klinisch imponieren durch Salzsäurebildung zumeist peranale Blutabgänge. Therapeutisch steht neben konservativ-medikamentösen Methoden die (endoskopische) Resektion im Vordergrund. Aus pathologischer Sicht erfordern Biopsien und Resektate solcher Läsionen auch aufgrund der grundsätzlich möglichen dysplastischen bzw. malignen Transformation eine sorgfältige Begutachtung.
Abstract
Heterotopic gastric mucosa is a rare finding in the rectum. Apart from two other hypotheses, a misdifferentiation of entodermal stem cells is the most widely accepted aetiopathogenetic assumption today. Due to acid secretion, the lesions predominantly manifest with hematochezia. Therapeutic options include medicinal therapy and particularly (endoscopic) removal. From the pathologist’s point of view a careful evaluation is required also in terms of basically possible dysplastic or malignant changes.
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Reis, H., Kerker, J., Schaefer, A. et al. Rektale Magenschleimhautheterotopie. Pathologe 32, 521–524 (2011). https://doi.org/10.1007/s00292-011-1461-z
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DOI: https://doi.org/10.1007/s00292-011-1461-z