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A concise review on bio-responsive polymers in targeted drug delivery system

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Abstract

Bio-responsive polymers are the cornerstone of the creation of keen structures which, after getting unique stimuli like biotic indications as well as pathological irregularities, exhibit engineered biomedical functions. The creation of innovative products in precision medicine (a type of medicine that uses a person’s own gene or protein knowledge to prevent, diagnose, or treat illness) has shown considerable promise in these stimulus-receptive schemes, and in recent years, there has been a lot of research on this topic. The goal of this analysis is to summaries the introductory consciousness and recent development of advanced bio-responsive technologies like in recent years, bio-responsive polymeric nanotherapeutics have emerged as an intriguing medium for safe and effective cancer treatment to promote tumor cell uptake and cause drug delivery at the target location. However, the bio-responsive polymer-based drug delivery system may suffer from drawbacks like the polymers may have safety issues and sometimes the stimuli fail to release the drugs incorporated into the systems resulting failure of the system. So, more research is needed to explore on the behavior of different bio-responsive polymers for development of strategic drug transport arrangement. In this article, we have focused on numerous bio-approachable polymers used for development of pH, temperature, magnetic field, light, sound responsive drug delivery system.

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Biological stimuli-sensitive polymeric drug delivery system

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Dipanjan Karati is thankful to Gitanjali college of Pharmacy for continuous support.

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  1. Department of Pharmaceutical Chemistry, Gitanjali College of Pharmacy, Birbhum, West Bengal, 731237, India

    Dipanjan Karati

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Karati, D. A concise review on bio-responsive polymers in targeted drug delivery system. Polym. Bull. 80, 7023–7045 (2023). https://doi.org/10.1007/s00289-022-04424-7

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