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Halloysite nanotubes/carbohydrate-based hydrogels for biomedical applications: from drug delivery to tissue engineering

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Abstract

The incorporation of various nanoparticles (NPs) into hydrogel networks led to a series of new structures that have gained massive attentions in biomedical research from both academic and industrial communities. Over the years, by incorporation of halloysite (Hal) nanotubes into three-dimensional (3D) hydrogel networks with biocompatible carbohydrate polymers as scaffolds, the design and synthesis of hydrogel nanocomposites with defined properties for specific biomedical applications were possible. In this review, Scopus, Science direct, PubMed, ISI web of knowledge, and Springer databases were searched from 2013 to 2020 to highlight appropriate studies in the field of biomedical applications of Hal/carbohydrate-based hydrogels.

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Authors and Affiliations

  1. Solid Tumor Research Center, Research Institute for Cellular and Molecular Medicine, Urmia University of Medical Sciences, 5715789400, Urmia, Iran

    Jafar Rezaie, Ali Akbari, Vahid Rahimkhoei & Hessam Jafari

  2. Department of Polymer Processing, Iran Polymer and Petrochemical Institute, P.O. Box 14965-115, Tehran, Iran

    Zohre Mehri Lighvani

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  1. Jafar Rezaie
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Rezaie, J., Akbari, A., Rahimkhoei, V. et al. Halloysite nanotubes/carbohydrate-based hydrogels for biomedical applications: from drug delivery to tissue engineering. Polym. Bull. 79, 4497–4513 (2022). https://doi.org/10.1007/s00289-021-03784-w

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