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Thermo-mechanical and antimicrobial properties of natural rubber-based polyurethane nanocomposites for biomedical applications

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Abstract

A polyester-type polyurethane (PU) was prepared using hydroxyl-terminated natural rubber (HTNR) as the soft polymer segments, 4,4-methylene dicyclohexyl diisocyanate (H12MDI) as the hard segments and 1,4-butane diol (BDO) as a chain extender. A simple one-shot bulk polymerization method using tetrahydrofuran (THF) as the solvent was chosen. The molar ratio of (H12MDI:HTNR:BDO) was fixed at 1.05:0.5:0.5. The pristine PU and its composite films with titanium nanoparticles (TiO2), silver nanoparticles (AgNPs) and benzoic acid (BA) were prepared with a constant 0.5 wt% loading of the antimicrobial fillers. The pristine PU and PU composite films were obtained by solution casting and drying at 60 °C in a vacuum oven. The effects of the antimicrobial fillers on the physical structure, mechanical properties, thermal properties, and antimicrobial activities were investigated. The SEM images showed that TiO2 and AgNPs aggregated. The aggregates reduced the films’ tensile strength as they obstructed the transfer of mechanical loads from PU matrix to the dispersed fillers. In contrast, BA was clearly well dispersed in the matrix giving much better mechanical properties (12 MPa tensile strength and 278% strain at break) and the PU–BA films were transparent. The PU–BA composites appear promising for biomedical applications.

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Acknowledgements

We are grateful to the Faculty of Science and Industrial Technology for the use of their laboratory facilities and to Assoc. Prof. Dr. Seppo Karrila for reviewing the manuscript. This work was supported by the government budget (or budget revenue) of Prince of Songkla University year 2015, Grant No. SIT590171d.

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Authors and Affiliations

  1. Faculty of Science and Industrial Technology, Prince of Songkla University, Surat Thani Campus, Surat Thani, 84000, Thailand

    Ekasit Anancharoenwong, Wannarat Chueangchayaphan, Natthida Rakkapao, Sutida Marthosa & Boonphop Chaisrikhwun

  2. Center of Excellence in Membrane Science and Technology, Faculty of Science, Prince of Songkla University, Hat Yai Campus, Songkhla, 90112, Thailand

    Natthida Rakkapao & Sutida Marthosa

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  1. Ekasit Anancharoenwong
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Correspondence to Ekasit Anancharoenwong.

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Anancharoenwong, E., Chueangchayaphan, W., Rakkapao, N. et al. Thermo-mechanical and antimicrobial properties of natural rubber-based polyurethane nanocomposites for biomedical applications. Polym. Bull. 78, 833–848 (2021). https://doi.org/10.1007/s00289-020-03137-z

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  • DOI: https://doi.org/10.1007/s00289-020-03137-z

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