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Synthesis of Biodegradable Poly(butylene terephthalate)/poly(ethylene glycol) (PBT/PEG) Multiblock Copolymers and Preparation of Indirubin Loaded Microspheres

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Summary

Biodegradable PBT/PEG copolymers were synthesized by macromolecular transesterification method, and were characterized by 1H-NMR and DSC. Alkaline degradation behavior was studied too. Indirubin loaded microspheres were prepared by O/W solvent evaporation method.

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Authors and Affiliations

  1. Department of Chemistry, Sichuan University, Chengdu, 610065, China

    Yan Wang

  2. Department of Metal Materials, Sichuan University, Chengdu, 610065, China

    CaiBing Liu, Yong Sheng, Jian Mao, GuoTao Chao, MingJing Tu & ZhiYong Qian

  3. State Key Laborotary of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China

    LinYu Fan

  4. Division of Bioengineering, National University of Singapore, 117576, Singapore

    Jun Li

Authors
  1. Yan Wang
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  2. CaiBing Liu
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  3. LinYu Fan
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  4. Yong Sheng
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  5. Jian Mao
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  6. GuoTao Chao
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  7. Jun Li
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  8. MingJing Tu
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  9. ZhiYong Qian
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Corresponding author

Correspondence to ZhiYong Qian.

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Wang, Y., Liu, C., Fan, L. et al. Synthesis of Biodegradable Poly(butylene terephthalate)/poly(ethylene glycol) (PBT/PEG) Multiblock Copolymers and Preparation of Indirubin Loaded Microspheres. Polym. Bull. 53, 147–154 (2005). https://doi.org/10.1007/s00289-004-0326-5

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  • DOI: https://doi.org/10.1007/s00289-004-0326-5

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