Correlation between thymidylate synthase and dihydropyrimidine dehydrogenase mRNA level and in vitro chemosensitivity to 5-fluorouracil, in relation to differentiation in gastric cancer

Erratum to: Cancer Chemother Pharmacol DOI 10.1007/s00280-007-0448-1

Unfortunately, wrong version of Fig. 5 was printed. The corrected figure is given here.

Fig. 5

Correlation between tumoral DPD levels and 5-FU sensitivity in undifferentiated (a) and differentiated group (b). Plots show the correlation between DPD: GAPDH RT-PCR product ratios of biopsied specimens and sensitivity to 5-FU measured by the MTT assay using formula: IR(%) = (1 – mean absorbance per gram of tumor specimen in the drug treated wells/mean absorbance per gram of tumor specimen in the non-drug treated control wells) × 100. Spearman’s rank correlation coeffcient was r = −0.401 in undifferentiated group and r = 0.126 in differentiated group. DPD was a predictive factor for sensitivity only in undifferentiated group (P = 0.011). The correlation was not statistically significant in differentiated group