Abstract
Thrombotic thrombocytopenic purpura (TTP) is a rare disease which, together with hemolytic uremic syndrome, is subsumed under thrombotic microangiopathy. After stem cell transplantation (SCT), this syndrome represents a possibly fatal complication with a higher incidence in allogeneic SCT than in autologous SCT. Although plasmapheresis offers an encouraging treatment modality in classic TTP, this seems less effective in bone marrow transplant-associated microangiopathy. This is probably due to a different etiology. We present a case of transplant-associated TTP with a fatal outcome despite multiple courses of plasmapheresis.
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Received: 11 November 1999 / Accepted: 23 February 2000
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Chemnitz, J., Fuchs, M., Blau, W. et al. Fatal thrombotic thrombocytopenic purpura as a rare complication following allogeneic stem cell transplantation. Ann Hematol 79, 527–529 (2000). https://doi.org/10.1007/s002770000187
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DOI: https://doi.org/10.1007/s002770000187