Skip to main content

Advertisement

Log in

Alemtuzumab induced acquired hemophilia A in multiple sclerosis: a case report

  • Letter to the Editor
  • Published:
Annals of Hematology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Comini-Frota ER et al (2020) Acquired hemophilia A and other autoimmune diseases after alemtuzumab therapy for multiple sclerosis: a report of two cases. Mult Scler Relat Disord 44:102181

    Article  PubMed  Google Scholar 

  2. Faissner S, Gold R (2018) Efficacy and Safety of the Newer Multiple Sclerosis Drugs Approved Since 2010. CNS Drugs 32(3):269–287

    Article  CAS  PubMed  Google Scholar 

  3. Collins PW et al (2007) Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors’ Organisation. Blood 109(5):1870–1877

    Article  CAS  PubMed  Google Scholar 

  4. Baker D et al (2017) Interpreting lymphocyte reconstitution data from the pivotal phase 3 trials of alemtuzumab. JAMA Neurol 74(8):961–969

    Article  PubMed  PubMed Central  Google Scholar 

  5. Hill-Cawthorne GA et al (2012) Long term lymphocyte reconstitution after alemtuzumab treatment of multiple sclerosis. J Neurol Neurosurg Psychiatry 83(3):298–304

    Article  PubMed  Google Scholar 

  6. Gounder K, Batt T, Dreyer M (2021) Two case reports of acquired haemophilia A as complications of alemtuzumab treatment for multiple sclerosis. BMJ Neurol Open 3(1):e000095

    Article  PubMed  PubMed Central  Google Scholar 

  7. Madeley J, Hodges G, Birchley A (2018) Development of acquired haemophilia A in a patient treated with alemtuzumab for multiple sclerosis. BMJ Case Rep 2018:bcr2018226588. https://doi.org/10.1136/bcr-2018-226588

  8. Pisa M et al (2019) Acquired haemophilia A as a secondary autoimmune disease after alemtuzumab treatment in multiple sclerosis: a case report. Mult Scler Relat Disord 27:403–405

    Article  CAS  PubMed  Google Scholar 

  9. McCaughan G, Massey J, Sutton I, Curnow J (2017) Acquired haemophilia A complicating alemtuzumab therapy for multiple sclerosis. BMJ Case Rep 2017:bcr2017223016. https://doi.org/10.1136/bcr-2017-223016

  10. Brink HS, Moll W, Sandberg Y (2020) Acquired haemophilia A after alemtuzumab treatment of multiple sclerosis. Br J Haematol 190(1):13

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

All authors contributed to manuscript drafting or critical review and final approval for submission.

Corresponding author

Correspondence to Ali Taher.

Ethics declarations

Informed consent

The patient gave informed consent.

Conflict of interest

The authors declare no competing interests.

Additional information

Publisher's note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Fawaz, H., Hodroj, M.H., Tarhini, H. et al. Alemtuzumab induced acquired hemophilia A in multiple sclerosis: a case report. Ann Hematol 102, 3271–3273 (2023). https://doi.org/10.1007/s00277-023-05370-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00277-023-05370-8

Navigation