Abstract
We evaluated the efficacy of ethanolamine oleate (EO) as a sclerosing agent for a symptomatic hepatic or renal cyst. Seven patients with symptomatic hepatic (n = 3) or renal cysts (n = 4) were treated by sclerotherapy with EO. The cyst size in the greater diameter ranged from 6 to 13 cm. The cyst was punctured under ultrasound guidance, and after all of the cyst’s content was aspirated, an iodized contrast agent was injected to check the absence of communication between the cyst and biliary tree, urinary tract, or vessels. Then, the solution of ethanolamine oleate–iopamidol mixture (EOI) of 10% of the volume of the cyst’s content was injected via catheter. After 30 min, the injected EOI was aspirated completely before catheter removal. A follow-up computed tomography scan was performed at 1 and 3 months after treatment. The volume of the cyst and its reduction rate was calculated. In addition, symptoms and complications were assessed. The volume of the cyst ranged from 64 to 636 ml (mean: 328 ml) before treatment. Three months after treatment, it ranged from 2 to 50 ml (mean: 15ml) and the reduction rate of the cyst’s volume was more than 90% on average. Symptoms caused by the cyst disappeared in all cases and no major complication was encountered. Although two patients had a low-grade fever after sclerotherapy, it was easily controlled. It is suggested that the sclerotherapy with EO might be a safe, effective, well-tolerated treatment for symptomatic hepatic or renal cysts.
Similar content being viewed by others
References
Bozkurt FB, Boyvat F, Tekin I,et al. (2001) Percutaneous sclerotherapy of a giant benign renal cyst with alcohol. Eur J Radiol 40:64–67
Matti I, Aaro L, Markku S, et al. (1988) Percutaneous aspiration and alcohol sclerotherapy for symptomatic hepatic cysts. Ann Surg 210:208–215
Christophe C, Charles A, Philippe D, et al. (1998) symptomatic hepatic cysts: treatment with single-shot injection of minocycline hydrochloride. Radiology 206:205–209
Tabata S, Ozono S, Otani T, et al. (1994) Percutaneous renal cyst puncture with CO2 instillation therapy. Acta Urol. Jpn. 40:475–478
Numata I, Chiba Y, Toyoda S, et al. (1988) Percutaneous managements of simple renal cysts. Jpn.J Urol Surg 6:539–544
Bean WJ (1981) Renal cysts, treatment with alcohol. Radiology 138:329–331
Giovanni S, Stefano P, Gian LS, et al. (1993) Percutaneous treatment of hepatic cysts by aspiration and sclerotherapy. Cardiovasc Intervent Radiol 16:81–84
Nakagawa H, Ohishi H, Yoshioka T, et al. (1984) Treatment of renal cyst with absolute ethanol using interventional ultrasound. J Med Imagi 4:969–973
Akiyama H, Ichikawa T, Nagai A, et al. (1996) Study on the sclerosing agent for the treatment of simple renal cysts. Jpn J Urol 87:1277–1280
Tanaka Y, Ogino M, Tokuda H, et al. (1996) Examination of percutaneous minocycline hydrochloride injection therapy for hepatic cyst by one puncture method. Jpn J Gastroenterol 93:828–836
Yamamoto Y, Matsuoka H, Yamane A, et al. (1994) Treatment of simple renal cyst with CO2 instillation. Rinsho Hinyoukika 48:1994–1998
Orikasa K (1989) Studies on the damage of the cultured endothelial cells and K-562 cells by sclerosants used for treatment of esophageal varices. Jpn J Gastroenterol 86:2365-2372
Hellstorm P, Tammela T, Kontturi M, et al. (1988) Ethanolamine oleate as a sclerosant for testicular hydroceles and epididymal cysts. Br J Urol 62:445–448
Bruce B, Roohollah S, Mary L, et al. (1998) Ethanolamine sclerotherapy of a renal cyst. J Urol 153:385–386
Mitani M, Kojima K, Kageyama J, et al. (1993) Hematoma in renal cyst; a case report of delayed complication with ethanol instillation therapy of renal cyst: Jpn J Clin Radiol 36:617–620
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Yamamoto, K., Sakaguchi, H., Anai, H. et al. Sclerotherapy for Simple Cysts with Use of Ethanolamine Oleate: Preliminary Experience. Cardiovasc Intervent Radiol 28, 751–755 (2005). https://doi.org/10.1007/s00270-004-0277-0
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00270-004-0277-0