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Impact of Topical Epinephrine with Xylocaine on Drainage After Axillary Lymph Node Dissection: A Randomized Controlled Trial

  • Surgery in Low and Middle Income Countries
  • Published:
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Abstract

Introduction

We evaluated the impact of topical epinephrine with xylocaine on drainage after axillary lymph node dissection.

Methods

Fifty-two women were randomized into two groups, epinephrine with xylocaine drainage (ED) and conventional drainage group (CD). The amount of drainage, duration of drainage catheter, incidence of seroma formation and wound infection were noted.

Results

The mean total drainage volume was less in ED group as compared to CD group (195 ml vs. 353 ml; p = .002). Drainage catheter was removed earlier in ED group as compared to CD group (5.07 + / − 0.99 days vs. 6.65 + / − 1.07 days; p = 0.0001). The incidence of seroma and wound infection was similar in two groups.

Conclusion

Topical epinephrine with xylocaine after axillary lymph node dissection results in significantly decreased drainage volume and duration of drainage.

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Authors and Affiliations

  1. Department of Surgery, NSCB Medical College, Jabalpur, Madhya Pradesh, 482003, India

    Prerna Dehariya, Namrata Agarwal, Sanjay Kumar Yadav, Pawan Agarwal & Dhananjaya Sharma

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Dehariya, P., Agarwal, N., Yadav, S.K. et al. Impact of Topical Epinephrine with Xylocaine on Drainage After Axillary Lymph Node Dissection: A Randomized Controlled Trial. World J Surg 47, 2761–2766 (2023). https://doi.org/10.1007/s00268-023-07139-6

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