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Mortality Related to Appendectomy; a Population Based Analysis over Two Decades in Finland

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Abstract

Object

To define the mortality rate of appendectomy patients and appendectomy-related risk factors.

Background

Appendectomy has been considered as a safe operation and negative appendectomies acceptable in order to avoid perforations. There are few publications on appendectomy-related mortality. Removal of a normal appendix has been suggested to be related to a higher mortality rate versus removal of an inflamed appendix.

Methods

Data on all appendectomy patients between 1990 and 2010 in Finland were retrieved from the Discharge Register of the National Institute for Health and Welfare and combined with data from the Death Certificate Register of Statistics Finland. Thirty-day mortality was identified and compared with overall mortality. Detailed information from death certificates of patients dying within 30-day post-surgery was collected and analyzed.

Results

Over the study period, the thirty-day post-appendectomy mortality rate was 2.1/1000. Increased mortality was found in patients over 60 years of age. Negative appendectomy and complicated appendicitis were related to mortality. The negative appendectomy rate was higher in patients older than 40 years of age. During the study period, both mortality and the rate of negative appendectomies decreased, while the rate of laparoscopic appendectomies increased.

Conclusions

Post-appendectomy mortality is related to both negative appendectomies and complicated appendicitis. Diagnostic accuracy is fundamental in the care of patients with acute appendicitis, especially in the elderly. Improved diagnostic accuracy may have reduced mortality over the last two decades in Finland.

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Acknowledgments

This study was conducted with the cooperation of researchers from the National Institute for Health and Welfare, and Statistics Finland.

Funding

This study received financial support from the Finnish Foundation for Research on Alimentary Tract and the Finnish Medical Society Duodecim.

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Correspondence to Tuomo Rantanen.

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None of the authors have any conflicts of interest.

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Kotaluoto, S., Ukkonen, M., Pauniaho, SL. et al. Mortality Related to Appendectomy; a Population Based Analysis over Two Decades in Finland. World J Surg 41, 64–69 (2017). https://doi.org/10.1007/s00268-016-3688-6

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  • DOI: https://doi.org/10.1007/s00268-016-3688-6

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