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A New Approach for Adipose Tissue Treatment and Body Contouring Using Radiofrequency-Assisted Liposuction


A new liposuction technology for adipocyte lipolysis and uniform three-dimensional tissue heating and contraction is presented. The technology is based on bipolar radiofrequency energy applied to the subcutaneous adipose tissue and subdermal skin surface. Preliminary clinical results, thermal monitoring, and histologic biopsies of the treated tissue demonstrate rapid preaspiration liquefaction of adipose tissue, coagulation of subcutaneous blood vessels, and uniform sustained heating of tissue.

We live in a culture preoccupied with both weight and body contour. North America also is a society in which obesity is an epidemic. It is no surprise then that liposuction continues to be the most commonly performed aesthetic procedure in the world. In 2007, 450,000 liposuction procedures were performed in the United States alone by board-certified plastic surgeons, and another 150,000 by nonplastic surgeon physicians, for a total 600,000 lipocontouring procedures, accounting for approximately 5% of all elective surgeries in the United States. It is estimated that the number of liposuction procedures will more than double over the next 5 years.

Coincident with the dramatic rise in liposuction procedures, the aging “baby boomer” population, with decreasing skin tone and advanced laxity, are seeking body contour procedures. A technology that effectively allows the physician to remove and contour adipose tissue with less bruising, swelling, and pain while simultaneously providing for significant soft tissue contraction would enjoy popular appeal.

Traditional tumescent, small-cannula, suction-assisted liposuction (SAL) is based on mechanical disruption of adipose tissue by a suction cannula moved manually through the subcutaneous space aspirating small fat clusters of adipose tissue through the openings in the cannula [4, 9, 11, 12, 21]. This traditional liposuction procedure of avulsing fat through a mechanically induced negative pressure requires a degree of effort on the part of the physician and can be quite traumatic for the patient.

Traditional SAL is less effective in secondary liposuction procedures and in fibrous areas, which do not enjoy significant skin contraction [13, 14]. The evolution of smaller vented cannulas, wetting solutions, and syringe aspiration techniques has refined the art of liposuction [57, 13, 14, 1618, 22]. In an attempt to improve the postoperative patient recovery profile of pain, swelling, and bruising, and to enhance skin contraction, physician effort, and effectiveness in secondary and fibrous cases, newer generations of energy-assisted liposuction technologies have been developed.

The technique of ultrasound-assisted liposuction, in which cavitational ultrasound energy is delivered through a probe to adipose tissue specifically cavitated and liquified, is shown to be less traumatic than SAL and may result in more skin contraction [2, 15, 20, 23, 24]. Power-assisted liposuction (PAL) is a commonly used technology that uses a variable-speed motor to provide reciprocating motion to the cannula, which in combination with the reciprocating action of the surgeon’s arm, facilitates removal of adipose tissue [3]. The principal advantage of PAL is treatment speed and economy of motion.

Most recently, laser-assisted lipolysis (LAL) has been popularized [1, 8, 10, 19]. With the LAL technique, small fiberoptic probes deliver thermal and micromechanical lipolysis to adipose tissue, reducing the need for traumatic adipose aspiration forces and pressures and leading to an improved recovery profile for the patient. One of the purported LAL benefits is enhanced skin contraction after application of the small fiber to the subdermal space and warming of the skin to a temperature of 40°C [1, 8, 10, 19].

Although LAL became popular because of a strong campaign directly to consumers highlighting diminished recovery pain and risk as well as the potential ability to tighten the skin through subdermal heating, its use remains limited by relatively slow treatment speed, poor control of heating uniformity, and risk of tissue burns.

The radiofrequency-assisted liposuction (RFAL) technique described in this report offers

  • Faster treatment

  • Reduced tissue trauma

  • Improved safety

  • Uniform heating of the skin and the subcutaneous layer

  • Potential skin contraction.

Materials and Methods

The RFAL procedure was performed for 20 patients and 40 lipoplasty zones. The average age of the 18 women and 2 men was 43.9 years (range, 17–56 years). All RFAL areas underwent tumescent anesthesia before application of the radiofrequency (RF) energy. All aspiration was performed using a standard blunt-nose Mercedes cannula (Grahams Medical Corp, Costa Mesa, CA) (2.4–3.7 mm). The body areas treated included hips (n = 16), abdomen (n = 14), outer (n = 2) and inner (n = 4) thighs, arms (n = 1), love handles (n = 2), and male breasts (n = 2) (Table 1).

Table 1 Treated areas

The RFAL body contour procedure was performed using the BodyTite system (Invasix Ltd, Yokneam, Israel). The BodyTite system’s bipolar RF handpiece is inserted into the subcutaneous tissue, as shown in Fig. 1. The internal electrode is inserted into the adipose tissue at the desired depth for adipose and blood vessel coagulation. This insulated internal electrode probe emits the RF current through a small conductive tip. The external electrode has a larger contact area and is applied to the skin surface, creating lower power density in the skin than in the adipose tissue. Up to 50 W of RF power is applied between the two electrodes. The RF power distribution between the electrodes is shown schematically in Fig. 2. The RF current creates heat and coagulates the adipose, vascular, and fibrous tissue in the operative area.

Fig. 1

Bipolar radiofrequency handpiece inserted into the body

Fig. 2

Power distribution between electrodes

In this study, electrode size and applied power were adjusted to provide adipose tissue liquefaction in the tissue between the internal and external electrodes and subnecrotic heating in the skin. Online, continuous skin temperature measurements with a negative feedback loop control of power were conducted by a temperature sensor embedded in the external electrode and confirmed by thermal camera FLIR A320 (FLIR Systems, Sausalito, CA).

Continuous online tissue impedance and power output between electrodes were monitored. During treatment, the parameters of the BodyTite device were set so that the system would reach 40°C and maintain that target temperature for 1 to 2 min. The typical RF energy introduced into the treated area was 100 J/cm2. Uniformity of temperature distribution was analyzed using thermal images and Researcher 2.9 of Flir Systems software.

In addition, two patients underwent RFAL to their lower abdominal tissue immediately before excision of this tissue through an abdominoplasty procedure. Several 6-mm excisional biopsies were taken at the end of the treatment to analyze the RFAL treatment effect on fat and skin. A control biopsy was taken from an immediately adjacent untreated area.

The objective of the study was to establish the range of optimal treatment parameters and the RFAL treatment technique for different anatomic zones and thicknesses of the fat layer. The main success indicators were

  • Safe treatment

  • Fast treatment

  • Easy technique

  • Uniform temperature distribution (±2°C)

  • Ability to maintain desired contraction temperatures for a consistent duration of time

  • Coagulation and liquefaction of adipose tissue

  • Blood vessel coagulation in the adipose layer.

The areas to be contoured were divided into distinct thermal zones of 10 × 15 cm. The discrete thermal zones corresponded to the length of the internal electrode and were selected to ensure a quick uniform adipose and vascular coagulation and a rise in temperature. Zones were selected and marked on the patient’s body. The cutoff temperature was set as high as 42°C. When measured skin temperature reached this thermal target point, the device automatically cut off the power and restored power only when the temperature fell below the preset value. The power used for treatment in each zone was set initially to 20 W and increased gradually up to 50 W if no warning signs such as temperature spikes, erythema, or intradermal vesicles were observed. After determination of the maximal safety power level, the zone was treated with RFAL until the temperature-controlled power cutoff limit was reached, which then was maintained at this level for 1 to 2 min to ensure uniform heating. Typical treatment power was 40 to 45 W.

Two depth settings were used for the treatment. The depth of 30 to 45 mm was used for treatment of deep fat. The end point for deep fat was reduction of mechanical tissue resistance. The superficial layer then was treated using a depth preset at 10 to 25 mm. A uniform desired tissue temperature elevation was the indication of successful treatment.

After the RF treatment, aspiration of the coagulated adipose tissue was performed using a standard vented microcannula. Aspiration and contouring of the zone was completed when the “pinch and roll” test indicated symmetric, even, and uniform fat reduction. Fat thickness, treated area, and total applied energy were documented to determine the volumetric RF dose required to perform the treatment according to the aforementioned criteria.


We compared the thermal effect created using RFAL BodyTite technology with the effect of LAL (SmartLipo MPX, Cynosure, Westford, MA) as the standards for thermal and nonthermal lipolysis and lipoplasty. For the speed of treatment, the gold standard remains PAL (Microaire Surgical Instruments, Charlottesville, VA).

Treatment Speed

The initial temperature of the treatment sites varied from 26 to 29°C. At a power output of 45 W, it took approximately 8 to 12 min to heat up a typical zone with a thermal zone of 15 × 10 cm and a thickness of 25 mm. This treatment speed of uniform heating is much faster than that of the available LAL devices. We believe that the high speed of treatment is achieved not only by the higher power of the device, but also from the more efficient use of applied power, which is not scattered from the treatment tip in all directions but concentrated in the treated zone between the two electrodes. The high speed of tissue heating facilitates the treatment of patients with large or multiple anatomic zones. In the current study, the treatment speed was comparable with that of ultrasound-assisted liposuction devices, but we believe that combination RFAL handpieces with simultaneous aspiration will make the treatment speed comparable with that of PAL.

Volumetric analysis of applied energy and treated volume showed that approximately 50 J/cm3 is required to reach the needed thermal effect in a lipoplasty zone of standard size. At an RF power of 40 to 50 W, the speed of volumetric treatment is in the range of 1 to 1.2 s/cm3.

Ease of Use

For a thermal sensor embedded in the external electrode, anticarbonization protection of the internal electrode and treatment depth control makes treatment safe, effective, and easy.

Uniformity of Temperature Distribution

Figure 3 shows the typical temperature distribution for an LAL treatment zone (5 × 5 cm) when an external infrared thermometer (Raytek Corporation, Santa Cruz, CA) indicates the required target temperature of 40°C. It can be seen that the LAL temperature distribution is not completely uniform and is concentrated in “hot spots.” Although the hot spots reach temperatures of 47°C, a significant part of the thermal zone is still cold and exhibits temperatures of below 35°C. Application of additional LAL energy creates a high risk of a burn in the “hot spots,” but ceasing treatment may lead to lack of uniform heating, poor skin contraction, and inconsistency of the results.

Fig. 3

Typical thermal image of the zone treated with laser-assisted lipolysis (LAL)

Using the temperature, impedance, and power control of the BodyTite device, we developed a new technique in which treatment is sustained at the target temperature for the treatment period at subnecrotic thermal levels to optimize soft tissue contraction. Closed-loop temperature and impedance control prevent thermal injury and facilitate longer treatment times at critical target temperatures, allowing all soft tissue in the treatment zone to reach a uniform temperature distribution. Figure 4 shows the uniformity of the temperature distribution after a BodyTite RFAL treatment.

Fig. 4

Typical thermal image of the zone treated with radiofrequency-assisted liposuction (RFAL)

The histogram in Fig. 5 obtained using Researcher 2.9 software for analysis of all thermal images shows uniformity of the treatment. It can be seen that the temperature distribution in the treatment zone after RFAL treatment exhibits twice the uniformity achieved during LAL.

Fig. 5

Temperature distribution in the thermal zone after treatment

Fat Necrosis

Histologic samples taken from the treated area show extensive destruction and coagulation of the adipocytes and adipose tissue. Figure 6 shows histologic images of fat from control biopsy (Fig. 6a) and posttreatment zones. Trichrome staining of the samples shows disruption and coagulation of adipocyte membranes and adipose tissue after the RFAL treatment (Fig. 6c).

Fig. 6

Adipose tissue from the control biopsy (a), after PAL (b), and after radiofrequency-assisted liposuction (RFAL) (c)

It can be seen that PAL creates channels in the adipose tissue with strong bleeding (Fig. 6b). Erythrocytes fill most of the space between fat cells. After RF-assisted treatment, the channel is free of blood, and strong fat cell membrane defragmentation is observed.

Blood Vessel Coagulation

Observation of post–RFAL-treated tissue after abdominoplasty shows no bleeding in the adipose fatty tissue to a 5- to 30-mm depth, whereas bleeding is observed from blood vessels in the subdermal area, as shown in Fig. 7. Histologic analysis of blood vessels in the RFAL-treated zone shows coagulation of small and medium-sized blood vessels, whereas the subdermal plexus vessels are not damaged (Fig. 8).

Fig. 7

Cross-section of treated adipose tissue

Fig. 8

Blood vessel from the radiofrequency-assisted liposuction (RFAL)-treated subcutaneous layer

Collagen Tissue and Skin Contraction

Histologic observation of connective tissue in the treatment area shows significant change in its structure, with coagulation of deep, reticular dermal collagen (Fig. 9). Early RFAL-induced soft tissue contraction appears very favorable and is better characterized and quantified with a long-term follow-up evaluation of 6 months. It appears that a powerful contraction and retraction of the entire subcutaneous fibrous and dermal matrix occurs after the RFAL thermal stimulation that can lead to impressive three-dimensional soft tissue contraction and contours (Figs. 10, 11, 12). We believe the necessary physiologic thresholds and criteria for soft tissue contraction, specifically maintenance of a critical temperature for a critical duration in the fibrous tissue of the adipose and subdermal regions, are optimized with the advanced BodyTite feedback controls.

Fig. 9

Collagen appearance. Control condition (a) and immediately after the treatment (b)

Fig. 10

Body shape appearance of a female patient before (left) and 6 months after treatment (right)

Fig. 11

Body shape appearance of a female patient before (left) and 6 months after treatment (right)

Fig. 12

Body shape appearance of a female patient before (left) and 6 months after treatment (right)

Treatment Safety

No complications or any long-lasting negative side effects were observed for any patients. All the patients experienced minimal pain, swelling, and ecchymosis. It is postulated that the reduced bruising observed was due to blood vessel coagulation in the treated zone before aspiration. The feedback control in the BodyTite handpiece allowed for the necessary sustained tissue heating to 40 to 42°C without thermal injury.


Radiofrequency-assisted liposuction is a promising technology for body contouring with the following apparent advantages:

  • Ability to heat a significant volume of tissue quickly and uniformly

  • Ability to control tissue heating through direct monitoring of temperature and tissue impedance.

  • Defragmentation of fat cells and coagulation of blood vessels in the treated zone, reducing bleeding and bruising

  • Obvious collagen denaturation after RFAL treatment

  • Significant contraction and retraction of adipose and dermal tissue after treatment.

The correlation between tissue-heating temperature, time, and body tightening requires further investigation but appears to offer an exciting new vista in nonexcisional body contouring.


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We thank Invasix Ltd for assistance in thermal measurements, and we appreciate Patricia Ganas for her assistance with preparing this report for publication. The chief of medical advisory board was compensated for fees and options by Invasix Ltd.

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Correspondence to Malcolm Paul.

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Paul, M., Mulholland, R.S. A New Approach for Adipose Tissue Treatment and Body Contouring Using Radiofrequency-Assisted Liposuction. Aesth Plast Surg 33, 687–694 (2009).

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  • Coagulation
  • Liposuction
  • Radiofrequency
  • Tightening