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Correction to: Cancer Immunology, Immunotherapy https://doi.org/10.1007/s00262-021-03027-x
The original version of this article unfortunately contained a mistake in Fig. 6. The corrected Fig. 6 is given in the next page.
Illustrated here are dynamic changes of immune cell populations and characteristics during the carcinogenic transition from gastroesophageal reflux disease (GERD) to Barrett’s esophagus (BE) and finally to esophageal cancer (EC) in the esophagus of this rat model. Inflammatory reaction is initiated around 10 weeks after the surgery and proliferative hyperplasia (PHP) of the esophagus epithelial cells is observed. Metformin could impact the modulation of pro-inflammatory reactions in esophageal carcinogenesis and host antitumor immunity by improving the immunosuppressive tumor microenvironment and immune evasion
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Takei, R., Miyashita, T., Takada, S. et al. Correction to: Dynamic switch of immunity and antitumor effects of metformin in rat spontaneous esophageal carcinogenesis. Cancer Immunol Immunother 71, 791–793 (2022). https://doi.org/10.1007/s00262-021-03039-7
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DOI: https://doi.org/10.1007/s00262-021-03039-7