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Quantitative MRI in distinguishing bladder paraganglioma from bladder leiomyoma

  • Kidneys, Ureters, Bladder, Retroperitoneum
  • Published:
Abdominal Radiology Aims and scope Submit manuscript

Abstract

Purpose

To investigate the feasibility of quantitative MRI in the differentiation of bladder paraganglioma from bladder leiomyoma.

Methods

From 2014 to 2021, 11 patients with bladder paraganglioma and 14 patients with bladder leiomyoma confirmed by surgical pathology were retrospectively collected. All patients underwent multiparametric scanning with a 3.0 T MR system. Quantitative parameters including the SI-ratio on T1WI between the solid component of tumours and piriformis, ADC value and E-rate of the solid component of tumours were assessed. Independent sample t test or Mann–Whitney U test was used to compare these parameters between the two groups. The diagnostic efficiency of the parameters was examined using ROC curve analysis and the DeLong test.

Results

There were significant differences in SI-ratio on T1WI (P < 0.001), ADC value (P = 0.002) and the E-rate (P = 0.040) between the paraganglioma group and the leiomyoma group. The cutoff value of SI-ratio on 3 leiomyoma was 1.241, and the AUC was 1.000 (0.858–1.000). The cutoff value of the ADC value was 0.979 × 10−3mm2/s, and the AUC was 0.907 (0.717–0.987). The cutoff value of E-rate was 98.7%, and the AUC was 0.714 (0.495–0.878). The AUCs of the SI-ratio on T1WI and ADC value were significantly higher than the E-rate AUC (P = 0.015 and 0.034, respectively).

Conclusion

Quantitative MRI can effectively distinguish bladder paraganglioma from bladder leiomyoma with the SI-ratio on T1WI or ADC value.

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Funding

This work was supported by the National Nature Science Foundation of China (Grant No.82071989); Natural Science Foundation of Guangdong Province (Grant No. 2021A1515012243); and the Kelin New Star Talent Program of The First Affiliated Hospital, Sun Yat-sen University (Grant No. R08028).

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Author notes

  1. Xiaoxiao Hu and Ke Wang contributed equally to this work, and they are co-first authors.

Authors and Affiliations

  1. Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, No.58 Zhongshanerlu Road, Guangzhou, 510080, Guangdong, People’s Republic of China

    Xiaoxiao Hu, Ke Wang, Mengya Sun, Chang Li, Huanjun Wang & Jian Guan

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  1. Xiaoxiao Hu
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Contributions

XHu: Conceptualization, Methodology, Writing—original draft. KW: Conceptualization, Methodology, Writing—original draft. MS: Investigation, Methodology. CL: Data curation, Investigation. HW: Investigation. JG: Conceptualization, Supervision, Writing—review & editing.

Corresponding author

Correspondence to Jian Guan.

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The institutional ethics committee has approved this retrospective study and has waived the requirement of informed consent.

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Hu, X., Wang, K., Sun, M. et al. Quantitative MRI in distinguishing bladder paraganglioma from bladder leiomyoma. Abdom Radiol 48, 1051–1061 (2023). https://doi.org/10.1007/s00261-023-03812-5

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