Skip to main content
Log in

Increasing CEUS utilization in the USA: a call to action for the adult and pediatric body imaging community

  • Perspective
  • Published:
Abdominal Radiology Aims and scope Submit manuscript

Abstract

Despite its well-established benefits and a powerful body of scientific literature supporting the efficacy of contrast-enhanced ultrasound (CEUS), it has faced challenges in being fully adopted as a diagnostic and problem-solving tool within the USA. This effort, written by experts in performance of and interpretation of CEUS, acts as a roadmap, for those interested in expanding CEUS within their facility. CEUS benefits from a Champion who is knowledgeable and passionate about its performance and who is capable of transferring evidence-based enthusiasm to others. They must be willing to do the legwork required for the successful implementation of a CEUS program, including increasing referrals, expanding applications, and encouraging the inclusion of CEUS into current and established guidelines. The ability of CEUS to resolve a wide range of indeterminate results which come from CT and MR scan represents one of the most compelling arguments for the use of CEUS, decreasing down-stream testing, and reducing time to diagnosis. As utilization grows, the benefits of CEUS will become apparent to other healthcare teams. However, the ultimate beneficiary of improved CEUS utilization will be the patients themselves, who will have greater access to a safe, speedy, cost effective, reliable, and radiation-free diagnostic imaging tool.

Graphical abstract

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Piscaglia F, Bolondi L, Italian Society for Ultrasound in M, Biology Study Group on Ultrasound Contrast A. The safety of Sonovue in abdominal applications: retrospective analysis of 23188 investigations. Ultrasound in medicine & biology. 2006;32(9):1369-75.

    Article  Google Scholar 

  2. Darge K, Papadopoulou F, Ntoulia A, et al. Safety of contrast-enhanced ultrasound in children for non-cardiac applications: a review by the Society for Pediatric Radiology (SPR) and the International Contrast Ultrasound Society (ICUS). Pediatric radiology. 2013;43(9):1063-73.

    Article  Google Scholar 

  3. Ntoulia A, Back SJ, Darge K. Contrast-enhanced ultrasound in children: a first-of-its-kind comprehensive compendium! Pediatric radiology. 2021;51(12):2115-6.

    Article  Google Scholar 

  4. Hu J, Bhayana D, Burak KW, Wilson SR. Resolution of indeterminate MRI with CEUS in patients at high risk for hepatocellular carcinoma. Abdom Radiol (NY). 2020;45(1):123-33.

    Article  Google Scholar 

  5. Bansal S, Gui J, Merrill C, Wong JK, Burak KW, Wilson SR. Contrast-enhanced US in Local Ablative Therapy and Secondary Surveillance for Hepatocellular Carcinoma. Radiographics : a review publication of the Radiological Society of North America, Inc. 2019;39(5):1302-22.

    Article  Google Scholar 

  6. Sawhney S, Wilson SR. Can Ultrasound With Contrast Enhancement Replace Nonenhanced Computed Tomography Scans in Patients With Contraindication to Computed Tomography Contrast Agents? Ultrasound quarterly. 2017;33(2):125-32.

    Article  Google Scholar 

  7. Sidhu PS, Cantisani V, Dietrich CF, et al. The EFSUMB Guidelines and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound (CEUS) in Non-Hepatic Applications: Update 2017 (Long Version). Ultraschall Med. 2018;39(2):e2-e44.

    Article  Google Scholar 

  8. Saftoiu A, Gilja OH, Sidhu PS, et al. The EFSUMB Guidelines and Recommendations for the Clinical Practice of Elastography in Non-Hepatic Applications: Update 2018. Ultraschall Med. 2019;40(4):425-53.

    Article  Google Scholar 

  9. Barr RG, Wilson SR, Lyshchik A, et al. Contrast-enhanced Ultrasound-State of the Art in North America: Society of Radiologists in Ultrasound White Paper. Ultrasound quarterly. 2020;36(4S Suppl 1):S1-S39.

  10. Barr RG, Wilson SR, Lyshchik A, et al. Contrast -Enhanced Ultrasound: State of the Art in North America. Ultrasound quarterly. 2020;36(3):206-17.

    Article  Google Scholar 

  11. Dietrich CF, Nolsøe CP, Barr RG, et al. Guidelines and Good Clinical Practice Recommendations for Contrast-Enhanced Ultrasound (CEUS) in the Liver-Update 2020 WFUMB in Cooperation with EFSUMB, AFSUMB, AIUM, and FLAUS. Ultrasound in medicine & biology. 2020;46(10):2579-604.

    Article  Google Scholar 

  12. ACR. LI-RADS CEUS 2017. 2017.

Download references

Author information

Authors and Affiliations

Authors

Contributions

SRW: Equipment support Philips, Siemens, and Samsung. Lantheus—Advisory panel. Philips Ultrasound—Speakers Bureau. CDM—no disclosure. KD: Bracco Diagnostics—Speakers Bureau and advisory panel. RGB: Philips Ultrasound—Speakers Bureau, research grant, and advisory panel. Siemens Ultrasound—Speakers Bureau and research grant. Canon Ultrasound—Speakers Bureau and research grant. Mindray Ultrasound—Speakers Bureau and research grant. Samsung Ultrasound—Speakers Bureau, research grant, and advisory panel. Hologic Ultrasound—Research grant and advisory panel. Bracco Diagnostics—Speakers Bureau and advisory panel. Lantheus—Advisory panel. GE Medical—Research grant. Thieme Publishers—Royalties. Elsevier Publishing—Royalties.

Corresponding author

Correspondence to Stephanie R. Wilson.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

All authors are members of the board of the International Contrast Ultrasound Society (ICUS).

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wilson, S.R., Merrill, C.D., Darge, K. et al. Increasing CEUS utilization in the USA: a call to action for the adult and pediatric body imaging community. Abdom Radiol 48, 418–423 (2023). https://doi.org/10.1007/s00261-022-03686-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00261-022-03686-z

Keywords

Navigation