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Complications of lymphoma in the abdomen and pelvis: clinical and imaging review

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Abstract

Involvement of the abdomen and pelvis is common in lymphoma. Nodal and extranodal abdominal and pelvic lymphoma may present with various complications. Complications are most common in high-grade lymphomas, especially diffuse large B-cell lymphoma. Complications may occur as the initial manifestation of lymphoma, during treatment course, or late following complete disease remission. Most complications are associated with worse prognosis and increased mortality. Imaging is essential in evaluation of disease extent and diagnosis of complications. Therefore, radiologists should be familiar with the clinical context and imaging features of abdominal and pelvic lymphoma complications. We provide a comprehensive, organ system-based approach, and clinical and imaging review of complications of abdominal and pelvic lymphoma along with radiologic images of illustrated cases of the most commonly encountered complications.

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MK contributed to the concept of the manuscript draft and literature review, wrote the manuscript, contributed images and captions, supervised the project, and provided final approval of the manuscript. TEA contributed to literature review, wrote the manuscript draft, and provided final approval of the manuscript. MAEA contributed to the manuscript editing and review, contributed images and captions, and provided final approval of the manuscript. MS contributed to the manuscript editing and review, contributed images and captions, and provided final approval of the manuscript.

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Correspondence to Mihran Khdhir.

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Khdhir, M., El Annan, T., El Amine, M.A. et al. Complications of lymphoma in the abdomen and pelvis: clinical and imaging review. Abdom Radiol 47, 2937–2955 (2022). https://doi.org/10.1007/s00261-022-03567-5

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