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LI-RADS treatment response lexicon: review, refresh and resolve with emerging data

  • Special Section: HCC Treatment
  • Published:
Abdominal Radiology Aims and scope Submit manuscript

Abstract

The imaging findings after loco regional treatment of hepatocellular carcinoma are variable based on the type of treatment used, the timing interval of imaging after treatment, and the cross-sectional modality used for treatment response assessment. Liver Imaging Reporting and Data System (LI-RADS) Treatment Response Algorithm (TRA) is a relatively new standardized method of evaluating treatment response after loco regional therapy to hepatocellular carcinoma. In this article, we provide an overview of the evolution of the treatment response algorithm, its current applicability and its outlook for the future. We will review current guidelines and discuss proposed changes to the algorithm as a means to continually improve LI-RADS TRA as an assessment tool post-loco regional treatment of hepatocellular carcinoma.

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Author notes

  1. Roopa Ram is the first author.

Authors and Affiliations

  1. University of Arkansas for Medical Sciences, 4301 W. Markham St, Little Rock, Ar, 72205, USA

    Roopa Ram

  2. Radiological Sciences, University of California, Irvine, 101 The City Drive South, Bldg. 1, Rt. 140, Mail Code: 5005, Orange, CA, 92868, USA

    Rony Kampalath

  3. Division of Abdominal Imaging and Interventions, Harvard Medical School, Beth Israel Deaconess Medical Center, Shapiro 4, 330 Brookline Avenue, Boston, MA, 02115, USA

    Anuradha S. Shenoy-Bhangle

  4. Department of Radiology and Biomedical Imaging, Yale University, 333 Cedar Street, New Haven, CT, 06510, USA

    Sandeep Arora

  5. Dept of Medical Imaging, Toronto General Hospital, University of Toronto, 585 University Ave, Toronto, ON, M5G2N2, Canada

    Ania Z. Kielar

  6. Abdominal and Cross-Sectional Interventional Radiology, University of Michigan, 1500 E Medical Center Dr, UH B2 A209R, Ann Arbor, MI48109, USA

    Mishal Mendiratta-Lala

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  1. Roopa Ram
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  2. Rony Kampalath
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Correspondence to Roopa Ram.

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Ram, R., Kampalath, R., Shenoy-Bhangle, A.S. et al. LI-RADS treatment response lexicon: review, refresh and resolve with emerging data. Abdom Radiol 46, 3549–3557 (2021). https://doi.org/10.1007/s00261-021-03149-x

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