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Characterization of benign hepatic tumors arising in fatty liver with SonoVue and pulse inversion US

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Abstract

Background

We describe the spectrum of contrast-enhancement patterns of benign hepatic tumors arising in fatty liver on contrast-enhanced ultrasound (US).

Methods

Sixteen patients (12 women and four men) with 27 benign hepatic tumors (17 hemangiomas, eight focal nodular hyperplasias, and two hepatocellular adenomas) arising in fatty liver underwent baseline and pulse inversion US after administration of SonoVue. Two experienced radiologists evaluated baseline echogenicity and dynamic enhancement pattern of each lesion in comparison with adjacent liver parenchyma.

Results

After administration of SonoVue, in the arterial phase 13 of 17 hemangiomas showed peripheral globular enhancement and one showed a rim of peripheral enhancement, followed by progressive centripetal fill-in, which was complete in 10 of 14 cases and incomplete in four. Three of 18 hemangiomas showed rapid and complete fill-in in the arterial phase. Eight of eight focal nodular hyperplasias became hyperechoic in comparison with adjacent liver parenchyma in the arterial phase and slightly hyperechoic or isoechoic in the portal venous and delayed phases. Both adenomas showed strong arterial contrast enhancement that became less intense in the portal venous and delayed phases.

Conclusion

Contrast-enhanced US after administration of SonoVue enables depiction of typical contrast-enhancement patterns in most benign hepatic tumors arising in fatty liver, thus providing useful clues for characterization.

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Authors and Affiliations

  1. Department of Radiology, University of Palermo, Via Del Vespro 127, Palermo, 90127, Italy

    T. V. Bartolotta, M. Midiri, M. Galia, R. Lagalla & A. E. Cardinale

  2. Emergency Department, Second Service of Radiology, S. Martino Hospital, Largo Benzi 10, Genova, 16132, Italy

    G. A. Rollandi

  3. Department of Radiology, Erasmus Medical Center, Dr. Molenwaterplein, 40, Rotterdam, 3015GD, The Netherlands

    F. Cademartiri

Authors
  1. T. V. Bartolotta
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  2. M. Midiri
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  3. M. Galia
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  4. G. A. Rollandi
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  5. F. Cademartiri
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  6. R. Lagalla
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  7. A. E. Cardinale
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Correspondence to T. V. Bartolotta.

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Bartolotta, T.V., Midiri, M., Galia, M. et al. Characterization of benign hepatic tumors arising in fatty liver with SonoVue and pulse inversion US. Abdom Imaging 32, 84–91 (2007). https://doi.org/10.1007/s00261-005-0074-5

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  • DOI: https://doi.org/10.1007/s00261-005-0074-5

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