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Cinematic rendering represents a transformative technique, altering the manner in which radiologists and other medical specialists perceive anatomical details and pathological conditions. Developed as a fusion of radiology and cinematography, cinematic rendering transcends traditional rendering methods, providing lifelike representations that bridge the gap between medical images and reality [1].
Cinematic rendering is a post-processing technique rooted in the segmentation of standard radiological images into photorealistic three-dimensional representations, facilitating spatial orientation [2]. Historically, its application has primarily centered on CT images [2,3,4,5], with sporadic instances noted in PET/CT [2]; however, its use in PET/MR remains unreported to date.
This image shows a cinematically rendered standard clinical [18F]FDG-PET/MR image (Signa PET/MR, GE HealthCare, Waukesha; MR image: T1-weighted LAVA-flex, repetition time 4.65 ms, echo time 1.82 ms, flip angle 15°, slice thickness 1.3 mm, spacing 2.6 mm, field of view 100 mm, total acquisition time 1:31 min; PET image: 245 MBq of [18F]FDG, bed time 1:30 min, reconstructed using block-sequential regularized expectation maximization) in a patient with an [18F]FDG-avid oropharyngeal carcinoma arising in the right-sided soft palate and palatine tonsil (arrow).
The cinematically rendered image presented here was retrospectively reconstructed from a standard clinical image dataset acquired within less than 2 min, using the software Cinematic Anatomy [1, 3, 6]. Such photorealistic images could potentially aid radiologists in reporting and surgeons in preoperative planning by offering crucial anatomical landmarks, enhancing visualization of subsurface structures, and complementing endoscopic images.
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All authors contributed to the conception and design. Image analysis / image compilation and design of the final image performed by M.H. First draft of manuscript written by M.H. All authors commented on previous versions of the manuscript. All authors read and approved the final version of the manuscript.
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Huellner, M.W., Engel, K., Morand, G.B. et al. Cinematic rendering of [18F]FDG-PET/MR. Eur J Nucl Med Mol Imaging (2024). https://doi.org/10.1007/s00259-024-06812-9
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DOI: https://doi.org/10.1007/s00259-024-06812-9