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3D-DESS MRI with CAIPIRINHA two- and fourfold acceleration for quantitatively assessing knee cartilage morphology

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Skeletal Radiology Aims and scope Submit manuscript

Abstract

Objectives

This study aimed to assess the diagnostic image quality and compare the knee cartilage segmentation results using a controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA)-accelerated 3D-dual echo steady-state (DESS) research package sequence in the knee.

Materials and Methods

A total of 64 subjects underwent both two- and fourfold CAIPIRINHA-accelerated 3D-DESS and DESS without parallel acceleration technique of the knee on a 3.0 T system. Two musculoskeletal radiologists evaluated the images independently for image quality and diagnostic capability following randomization and anonymization. The consistency of automatic segmentation results between sequences was explored using an automatic knee cartilage segmentation research application. The descriptive statistics and inter-observer and inter-method concordance of various acceleration sequences were investigated. P values < .05 were considered significant.

Results

For image quality evaluation, the image signal-to-noise ratio and contrast-to-noise ratio decreased with the decrease in scanning time. However, it is accompanied by the reduction of artifacts. Using 3D-DESS without parallel acceleration technique as the standard for cartilage grading diagnosisand the diagnostic agreement of two- and fourfold CAIPIRINHA-accelerated 3D-DESS was good, kappa value was 0.860 (P < .001) and 0.804 (p < 0.001), respectively. Regarding cartilage defects, the sensitivity and specificity of the twofold acceleration 3D-CAIPIRINHA-DESS were 95.56% and 97.70%, and the fourfold CAIPIRINHA-accelerated 3D-DESS were 91.49% and 97.65%, respectively. The intraclass correlation coefficients of various sequences in cartilage segmentation were almost all greater than 0.9.

Conclusion

The CAIPIRINHA-accelerated 3D-DESS sequence maintained comparable diagnostic and segmentations performance of knee cartilage after a 60% scan time reduction.

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Data availability

The data are available from the corresponding author on reasonable request.

Abbreviations

CAIPIRINHA:

Controlled aliasing in parallel imaging results in higher acceleration

DESS:

Dual echo steady-state

2D:

2-Dimensional

3D:

3-Dimensional

OA:

Osteoarthritis

MRI:

Magnetic resonance imaging

FISP:

Fast imaging with steady-state precession

PSIF:

Reverse fast imaging with steady state precession

TE:

Echo time

TR:

Repetition time

FSE:

Fast spin echo

VIBE:

Volumetric interpolated breath-hold examination

TSE:

Turbo spin echo

SNR:

Signal noise ratio

CNR:

Contrast noise ratio

ROI:

Region of interest

FOV:

Field of view

SI:

Signal intensity

SIT:

Signal intensity of each other tissue

SD:

Standard deviation of background noise

DICOM:

Digital imaging and communications in medicine

ICC:

Intraclass correlation coefficient

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Authors and Affiliations

  1. Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095, Jiefang Road, Wuhan City, 430030, Hubei Province, China

    Donglin Wen, Bowen Hou, Yi Wang, Gang Wu & Xiaoming Li

  2. MR Collaboration, Siemens Healthineers Ltd., Shanghai, China

    Xiaoyue Zhou

  3. Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China

    Qiong Zhang

  4. Siemens Healthcare GmbH, Erlangen, Germany

    Esther Raithel

Authors
  1. Donglin Wen
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  2. Xiaoyue Zhou
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  6. Yi Wang
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  7. Gang Wu
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Correspondence to Gang Wu or Xiaoming Li.

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Conflicts of interest

Xiaoyue Zhou is an employee of Siemens Healthineers Ltd., Shanghai, China. Qiong Zhang is an employee of Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China., Esther Raithel is an employee of Siemens Healthcare GmbH, Erlangen, Germany. The remaining authors have no conflicts of interest.

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Wen, D., Zhou, X., Hou, B. et al. 3D-DESS MRI with CAIPIRINHA two- and fourfold acceleration for quantitatively assessing knee cartilage morphology. Skeletal Radiol (2024). https://doi.org/10.1007/s00256-024-04605-7

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  • DOI: https://doi.org/10.1007/s00256-024-04605-7

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