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The value of chest and skeletal staging studies in conventional chondrosarcoma

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Abstract

Objective

To determine the value of chest and skeletal staging in patients presenting with conventional chondrosarcoma (CS).

Materials and methods

Retrospective review of patients with CS diagnosed between January 2007 and December 2019. Data collected included age, sex, skeletal location and results of chest CT and whole-body bone scintigraphy (WB-BSc) obtained at initial diagnosis. The histological tumour grade based on surgical resection or needle biopsy was classified as low-grade (LGCT), high-grade (HGCT) and dedifferentiated (DD-CS). Findings of chest CT and WB-BSc were correlated with tumour grade.

Results

Four hundred twenty patients were included (234 males and 186 females with mean age 54.5 years, range 9–91 years). The major long bones were involved in 205 cases, the flat bones in 166 cases, the mobile spine in 14 cases and the small bones of the hands and feet in 35 cases. Three hundred fifty tumours were central in location, 39 peripheral and 31 on the surface of the bone. There were 151 LGCTs, 196 HGCTs and 73 DD-CSs. Of patients with LGCT, 41.7% underwent chest CT and 25.2% WB-BSc. Of patients with HGCT, 95.4% underwent chest CT and 76.5% WB-BSc. Of patients with DD-CS, 98.6% underwent chest CT and 86.3% WB-BSc. Metastases were diagnosed in 2 (3.3%) chest CT studies and 0 WB-BSc in LGCT, in 8 (4.3%) chest CT studies and 0 WB-BSc in HGCT and in 21 (30%) chest CT studies and 6 (21%) WB-BSc in DD-CS.

Discussion

Staging chest CT and WB-BSc is of little or no value except in DD-CS.

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Authors and Affiliations

  1. London North West Healthcare NHS Trust, London, UK

    Ines Oliveira

  2. The Royal National Orthopaedic Hospital, London, UK

    Nehal Singla & Asif Saifuddin

  3. Chelsea and Westminster NHS Trust, Stanmore, UK

    Anesh Chavda

Authors
  1. Ines Oliveira
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  2. Nehal Singla
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  3. Anesh Chavda
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  4. Asif Saifuddin
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Corresponding author

Correspondence to Ines Oliveira.

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The study was approved by the local Research and Innovation Centre of the Institute of Orthopaedics under the Integrated Research Application System number 262826, with no requirement for informed patient consent.

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The authors declare that they have no conflict of interest.

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Oliveira, I., Singla, N., Chavda, A. et al. The value of chest and skeletal staging studies in conventional chondrosarcoma. Skeletal Radiol 50, 125–135 (2021). https://doi.org/10.1007/s00256-020-03539-0

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  • DOI: https://doi.org/10.1007/s00256-020-03539-0

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