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Anaplastic large cell lymphoma presenting as an epiphyseal lytic lesion—a case report with clinico-pathologic correlation

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Abstract

Anaplastic large cell lymphoma (ALCL) is predominantly a systemic disease with nodal involvement, but extranodal involvement can occur either as the primary presentation or during the disease course. Primary epiphyseal involvement is extremely rare with lymphomas. This case report illustrates an 8-year old boy who first presented with pain over the right upper extremity, which was initially treated as epiphyseal osteomyelitis. A few weeks later, he presented with abdominal pain and an abdominal wall mass, which on biopsy proved to be an anaplastic large-cell lymphoma.

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Authors and Affiliations

  1. 1289 Swan Lake Drive Apt 306, Charlottesville, VA, 22902, USA

    Varatharaj Mounasamy

  2. Nemours Children’s Clinic, Orlando, FL, USA

    Varatharaj Mounasamy

  3. Department of Pathology, Orlando Regional Medical Center, Orlando, FL, USA

    Stephen Berns

  4. Department of Diagnostic Imaging, Children’s Hospital of Eastern Ontario, Ottawa, Canada

    E. Michel Azouz

  5. Hematology Division, Nemours Children’s Clinic, Orlando, FL, USA

    Vincent Giusti

  6. Nemours Children’s Clinic, Orlando, FL, USA

    D. Raymond Knapp

Authors
  1. Varatharaj Mounasamy
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  2. Stephen Berns
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  3. E. Michel Azouz
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  4. Vincent Giusti
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  5. D. Raymond Knapp
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Corresponding author

Correspondence to Varatharaj Mounasamy.

Additional information

Study conducted at the Nemour’s Children’s Clinic and Orlando Regional medical center, Orlando, Florida.

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Mounasamy, V., Berns, S., Azouz, E.M. et al. Anaplastic large cell lymphoma presenting as an epiphyseal lytic lesion—a case report with clinico-pathologic correlation. Skeletal Radiol 35, 619–623 (2006). https://doi.org/10.1007/s00256-006-0087-3

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  • DOI: https://doi.org/10.1007/s00256-006-0087-3

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