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Microbial co-culturing systems: butanol production from organic wastes through consolidated bioprocessing

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Abstract

Biobutanol can be indigenously synthesized by solventogenic Clostridium species; however, these microorganisms possess inferior capability of utilizing abundant and renewable organic wastes, such as starch, lignocellulose, and even syngas. The common strategy to achieve direct butanol production from these organic wastes is through genetic modification of wild-type strains. However, due to the complex of butanol synthetic and hydrolytic enzymes expression systems, the recombinants show unsatisfactory results. Recently, setting up microbial co-culturing systems became more attractive, as they could not only perform more complicated tasks, but also endure changeable environments. Hence, this mini-review comprehensively summarized the state-of-the-art biobutanol production from different substrates by using microbial co-culturing systems. Furthermore, strategies regarding establishment principles of microbial co-culturing systems were also analyzed and compared.

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Acknowledgements

This work was supported by the Jiangsu Province Natural Science Foundation for Youths (No. BK20170993, BK20170997); the Jiangsu Synergetic Innovation Center for Advanced Bio-Manufacture; the Project of State Key Laboratory of Materials-Oriented Chemical Engineering (KL16-08); the Key Science and Technology Project of Jiangsu Province (BE2016389); the Key Laboratory of Development and Application of Rural Renewable Energy, Biogas Institute of Ministry of Agriculture, China; and the National Natural Science Foundation of China (No. 21706125, No. 21727818, No. 21706124, No. 31700092).

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Authors and Affiliations

  1. State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Puzhu South Road 30#, Nanjing, 211800, People’s Republic of China

    Yujia Jiang, Ting Zhang, Jiasheng Lu, Wenming Zhang, Weiliang Dong, Jie Zhou, Min Jiang & Fengxue Xin

  2. Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University, Nanjing, 211800, People’s Republic of China

    Wenming Zhang, Weiliang Dong, Jie Zhou, Min Jiang & Fengxue Xin

  3. Institute of Microbiology and Biotechnology, University of Ulm, 89069, Ulm, Germany

    Peter Dürre

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  1. Yujia Jiang
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  2. Ting Zhang
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  8. Min Jiang
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  9. Fengxue Xin
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Correspondence to Min Jiang or Fengxue Xin.

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Jiang, Y., Zhang, T., Lu, J. et al. Microbial co-culturing systems: butanol production from organic wastes through consolidated bioprocessing. Appl Microbiol Biotechnol 102, 5419–5425 (2018). https://doi.org/10.1007/s00253-018-8970-0

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  • DOI: https://doi.org/10.1007/s00253-018-8970-0

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