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New developments in the trace analysis of organic water pollutants

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Abstract

Challenging tasks, increasing demands, and new generations of powerful analytical instruments initiated considerable progress in aquatic environmental analysis and led to a considerable improvement of analytical performance during the last few years. The ever growing number of emerging pollutants is tackled by specific and highly sensitive analytical methods with detection limits of a few nanogram per liter and even lower. Wide-scope monitoring techniques and multiclass and multiresidue analysis allow for the simultaneous determination of hundreds of compounds. The high mass resolution capability and mass accuracy of advanced mass spectrometric instruments, i.e., time-of-flight (TOF) MS or Fourier transform (FT)–Orbitrap MS, enable combined target and non-target analysis, including the identification of metabolites and abiotic degradation products. This minireview highlights some of the most recent developments in the trace analysis of important organic water pollutants and focuses on some specific groups of emerging contaminants, i.e., pharmaceuticals, flame retardants, disinfection by-products, surfactants, per- and polyfluorinated compounds, benzotriazoles, and benzothiazoles, as well as on the identification of transformation products and on non-target analysis. References were selected according to their exemplary and innovative character and to their practical relevance.

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References

  • Abdallah MAE, Ibarra C, Neels H, Harrad S, Covaci A (2008) Comparative evaluation of liquid chromatography–mass spectrometry for the determination of hexabromocyclododecanes and their degradation products in indoor dust. J Chromatogr A 1190:333–341

    Article  CAS  Google Scholar 

  • Alaee M, Arias P, Sjödin A, Bergman A (2003) An overview of commercially used brominated flame retardants, their applications, their use patterns in different countries/regions and possible modes of release. Environ Int 29:683–689

    Article  CAS  Google Scholar 

  • Al-Odaini NA, Zakaria MP, Yaziz MI, Surif S (2010) Multi-residue analytical method for human pharmaceuticals and synthetic hormones in river water and sewage effluents by solid-phase extraction and liquid-chromatography–tandem mass spectrometry. J Chromatogr A 1217:6791–6806

    Article  CAS  Google Scholar 

  • Andresen JA, Grundmann A, Bester K (2004) Organophosphorus flame retardants and plasticizers in surface waters. Sci Total Environ 332:155–166

    Article  CAS  Google Scholar 

  • Benvenuto F, Marin JM, Sancho JV, Canobbio S, Mezzanotte V, Hernandez F (2010) Simultaneous determination of triazines and their main transformation products in surface and urban wastewater by ultra-high-pressure liquid chromatography–tandem mass spectrometry. Anal Bioanal Chem 397:2791–2805

    Article  CAS  Google Scholar 

  • Berger U, Kaiser MA, Kärrman A, Barber JL, van Leeuwen SPJ (2011) Recent developments in trace analysis of poly- and perfluoroalkyl substances. Anal Bioanal Chem 400:1625–1635

    Article  CAS  Google Scholar 

  • Bester K, Huehnerfuss H, Lange W, Theobald N (1997) Results of non-target screening of lipophilic organic pollutants in the German Bight I: benzothiazoles. Sci Total Environ 207:111–118

    Article  CAS  Google Scholar 

  • Breedveld GD, Roseth R, Sparrevik M, Hartnik T, Hem L (2003) Persistence of the de-icing additive benzotriazole at an abandoned airport. Water Air Soil Poll Focus 3:91–101

    Article  CAS  Google Scholar 

  • Brosillon S, Lemasle M, Renault E, Tozza D, Heim V, Laplanche A (2009) Analysis and occurrence of odorous disinfection by-products from chlorination of amino acids in three different drinking water treatment plants and corresponding distribution networks. Chemosphere 77:1035–1042

    Article  CAS  Google Scholar 

  • Brownlee BG, Carey JH, MacInnis GA, Pellizzari IT (1992) Aquatic environmental chemistry of 2-(thiocyanomethylthio)benzothiazole and related benzothiazoles. Environ Toxicol Chem 11:1153–1168

    Article  CAS  Google Scholar 

  • Bruzzoniti M, DeCarlo RM, Sarzanini C (2008) Determination of sulfonic acids and alkylsulfates by ion chromatography in water. Talanta 75:734–739

    Article  CAS  Google Scholar 

  • Bueno MJM, Uclés S, Hernando MD, Fernández-Alba AR (2011) Development of a solvent-free method for the simultaneous identification/quantification of drugs of abuse and their metabolites in environmental water by LC-MS/MS. Talanta 85:157–166

    Article  CAS  Google Scholar 

  • Calisto V, Esteves VI (2009) Psychiatric pharmaceuticals in the environment. Chemosphere 77:1257–1274

    Article  CAS  Google Scholar 

  • Campone L, Piccinelli AL, Östman C, Rastrelli L (2010) Determination of organophosphorous flame retardants in fish tissues by matrix solid-phase dispersion and gas chromatography. Anal Bioanal Chem 397:799–806

    Article  CAS  Google Scholar 

  • Cancilla D, Martinez J, van Aggelen GC (1998) Detection of aircraft deicing/antiicing fluid additives in a perched water monitoring well at an international airport. Environ Sci Technol 32:3834–3835

    Article  CAS  Google Scholar 

  • Cancilla DA, Baird JC, Rosa R (2003) Detection of aircraft deicing additives in groundwater and soil samples from Fairchild Air Force Base, a small to moderate user of deicing fluids. Bull Environ Contam Toxicol 70:868–875

    Article  CAS  Google Scholar 

  • Charrois JWA, Arend MW, Froese KL, Hrudey SE (2004) Detecting N-nitrosamines in drinking water at nanogram per liter levels using ammonia positive chemical ionization. Environ Sci Technol 38:4835–4841

    Article  CAS  Google Scholar 

  • Charrois JWA, Boyd JM, Froese KL, Hrudey SE (2007) Occurrence of N-nitrosamines in Alberta public drinking-water distribution systems. J Environ Eng 6:103–114

    Article  CAS  Google Scholar 

  • Chen W-H, Young TM (2008) NDMA Formation during chlorination and chloramination of aqueous diuron solutions. Environ Sci Technol 42:1072–1077

    Article  CAS  Google Scholar 

  • Cheng X, Shi H, Adams CD, Timmons T, Ma Y (2010) Simultaneous screening of herbicide degradation byproducts in water treatment plants using high performance liquid chromatography-tandem mass spectrometry. J Agricult Food Chem 58:4588–4593

    Google Scholar 

  • Cherta L, Beltran J, Portolés T, Hernández F (2011) Multiclass determination of 66 organic micropollutants in environmental water samples by fast gas chromatography–mass spectrometry. Anal Bioanal Chem. doi:10.1007/s00216-011-5423-3

  • Corsi SR, Zitomer DH, Field JA, Cancilla DA (2003) Nonylphenolethoxylates and other additives in aircraft deicers, antiicers, and waters receiving airport runoff. Environ Sci Technol 37:4031–4037

    Article  CAS  Google Scholar 

  • Covaci A, Voorspoels S, Abdallah MAE, Geens T, Harrad S, Law RJ (2009) Analytical and environmental aspects of the flame retardant like tetrabromobisphenol-A and its derivatives. J Chromatogr A 1216:346–363

    Article  CAS  Google Scholar 

  • Covaci A, Harrad S, Abdallah MAE, Ali N, Law RJ, Herzke D, de Wit CA (2011) Novel brominated flame retardants: a review of their analysis, environmental fate and behaviour. Environ Int 37:532–556

    Article  CAS  Google Scholar 

  • Crey-Desbiolles C, Cavalli S, Polesello S, Valsecchi S (2009) Automated determination of linear alkylbenzene sulphonate (LAS) in wastewater treatment plants effluents using online solid-phase extraction followed by HPLC with fluorescence detection. Tensid Surf Detergents 46:346–351

    CAS  Google Scholar 

  • de Wit CA (2002) An overview of brominated flame retardants in the environment. Chemosphere 46:583–624

    Article  Google Scholar 

  • D'eon JC, Mabury SA (2011) Exploring indirect sources of human exposure to perfluoroalkyl carboxylates (PFCAs): evaluating uptake, elimination, and biotransformation of polyfluoroalkyl phosphate esters (PAPs) in the rat. Environ Health Persp 119:344–350

    Article  CAS  Google Scholar 

  • Dimitrov S, Pavlov T, Nedelcheva D, Reuschenbach P, Silvani M, Bias R, Comber M, Low L, Lee C, Parkerton T, Mekenyan O (2007) A kinetic model for predicting biodegradation. SAR QSAR Environ Res 18:443–457

    Article  CAS  Google Scholar 

  • DIN 38407–41 (2011) Bestimmung ausgewählter leichtflüchtiger organischer Verbindungen in Wasser–Verfahren mittels Gaschromatographie und Massenspektrometrie (GC-MS) nach Headspace-Festphasenmikroextraktion (HS-SPME). Beuth, Berlin

    Google Scholar 

  • DIN 38407–42 (2011) Bestimmung ausgewählter polyfluorierter Verbindungen (PFC) in Wasser–Verfahren mittels Hochleistungs-Flüssigchromatographie und massenspektrometrischer Detektion (HPLC-MS/MS) nach Fest-Flüssig-Extraktion. Beuth, Berlin

    Google Scholar 

  • Dinglasan MJA, Ye Y, Edwards EA, Mabury SA (2004) Fluorotelomer alcohol biodegradation yields poly-and perfluorinated acids. Environ Sci Technol 38:2857–2864

    Article  CAS  Google Scholar 

  • Directive (2003) Directive 2003/11/EC of the European Parliament and of the Council of 6 February 2003. Official Journal L 042, 15/02/2003

  • Dodd MC, Kohler H-PE, von Gunten U (2009) Oxidation of antibacterial compounds by ozone and hydroxyl radical: elimination of biological activity during aqueous ozonation processes. Environ Sci Technol 43:2498–2504

    Article  CAS  Google Scholar 

  • Dodd MC, Rentsch D, Singer HP, Kohler H-PE, von Gunten U (2010) Transformation of β-lactam antibacterial agents during aqueous ozonation: reaction pathways and quantitative bioassay of biologically-active oxidation products. Environ Sci Technol 44:5940–5948

    Article  CAS  Google Scholar 

  • Dreyer A, Matthias V, Weinberg I, Ebinghaus R (2010) Wet deposition of poly- and perfluorinated compounds in Northern Germany. Environ Poll 158:1221–1227

    Article  CAS  Google Scholar 

  • Eganhouse RP, Pontolillo J, Gaines RB, Frysinger GS, Gabriel FLP, Kohler H-PE, Giger W, Barber LB (2009) Isomer-specific determination of 4-nonylphenols using comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry. Environ Sci Technol 43:9306–9313

    Article  CAS  Google Scholar 

  • Ellis DA, Martin JW, De Silva AO, Mabury SA, Hurley MD, Andersen MPS, Wallington TJ (2004) Degradation of fluorotelomer alcohols: a likely atmospheric source of perfluorinated carboxylic acids. Environ Sci Technol 38:3316–3321

    Article  CAS  Google Scholar 

  • Ellis LBM, Roe D, Wackett LP (2006) The University of Minnesota biocatalysis/biodegradation database: The first decade. Nucleic Acids Res 34:D517–D521

    Article  CAS  Google Scholar 

  • EU (2008) Guideline 2000/60/EG from 23 Oct. 2000, changed by. Off J Europ Union L 348(95), 24/12/2008)

  • European Commission (1995) Commission regulation (EC) No 2268/95 of 27 September 1995 concerning the 2nd list of priority substances as foreseen under Council Regulation (EEC) No 793/93. Off J Europ Union L 231:18–19

    Google Scholar 

  • European Commission (2000a) Commission regulation (EC) No 2364/2000 of 25 October 2000 concerning the fourth list of priority substances as foreseen under Council Regulation (EEC) No 793/93. Off J Europ Union L 273:5–7

    Google Scholar 

  • European Commission (2000b) Directive 2000/60/EC of the European Parliament and the Council of 23 October 2000 establishing a framework for community action in the field of water policy. Off J Europ Union L 327

  • European Commission (2004) Regulation (EC) No 648/2004 of the European Parliament and of the Council of 31 March 2004 on detergents. Off J Europ Union L 104:1–35

    Google Scholar 

  • European Commission (2006) Directive 2006/118/EC of the European Parliament and of the Council of 12th December 2006 on the protection of ground water against pollution and deterioration. Off J Europ Union L372/19

  • European Commission (2008a) EU risk assessment report: tris(2-chloro-1-methylethyl) phosphate, TCPP. May, 2008

  • European Commission (2008b) EU risk assessment report: tris(2-chloro-1[chloromethyl]ethyl) phosphate, TDCP. May, 2008

  • European Commission (2009) EU risk assessment report: tris(2-chloroethyl) phosphate, TCEP. Final approved version, July, 2009

  • European Court of Justice (2008) Cases C-14/06 and C-295/06, Judgement of the Court, 1 April 2008, Directive 2002/95/EC and Commission Decision 2005/717/EC; http://curia.europa.eu (Accessed 13 May 2011)

  • European Flame Retardants Association (2011) Flame retardants: integral to fire safety. http://www.cefic-efra.com/content/Default.asp?PageID=179. Accessed 13 November 2011

  • Fatta-Kassinos D, Meric S, Nikolaou A (2011a) Pharmaceutical residues in environmental waters and wastewater: current state of knowledge and future research. Anal Bioanal Chem 399:251–275

    Article  CAS  Google Scholar 

  • Fatta-Kassinos D, Vasquez MI, Kümmerer K (2011b) Transformation products of pharmaceuticals in surface waters and wastewater formed during photolysis and advanced oxidation processes—degradation, elucidation of byproducts and assessment of their biological potency. Chemosphere 85:693–709

    Article  CAS  Google Scholar 

  • Fiehn O, Reemtsma T, Jekel M (1994) Extraction and analysis of various benzothiazoles from industrial wastewater. Anal Chim Acta 295:297–305

    Article  CAS  Google Scholar 

  • Fink U, Hajduk F, Mori H, Yang W (2008) Flame retardants, specialty chemicals. SRI Consulting, December 2008

  • Freuze I, Brosillon S, Herman D, Laplanche A, Démocrate C, Cavard J (2004) Odorous products of the chlorination of phenylalanine in water: formation, evolution and quantification. Environ Sci Technol 38:4134–4139

    Article  CAS  Google Scholar 

  • Freuze I, Brosillon S, Laplanche A, Tozza D, Cavard J (2005) Effect of chlorination on the formation of odorous disinfection by-products. Water Res 39:2636–2642

    Article  CAS  Google Scholar 

  • Fries E (2011) Determination of benzothiazole (BT) in untreated waste water using polar phase stir bar sorptive extraction (SBSE) and GC-MS. Anal Chim Acta 689:65–68

    Article  CAS  Google Scholar 

  • Fries E, Mihajlović I (2011) Pollution of soils with organophosphorus flame retardants and plasticizers. J Environ Monit 13:2692–2694

    Article  CAS  Google Scholar 

  • Fries E, Puettmann W (2001) Occurrence of organophosphate esters in surface water and ground water of Germany. J Environ Monit 3:621–626

    Article  CAS  Google Scholar 

  • Fries E, Puettmann W (2003) Monitoring of the organophosphate esters TBP, TCEP, and TBEP in river water and ground water (Oder, Germany). J Environ Monit 5:346–352

    Article  CAS  Google Scholar 

  • Fries E, Klasmeier J, Gocht T (2011) Occurrence and distribution of benzothiazole in the Schwarzbach watershed (Germany). J Environ Monit 13:2838–2843

    Article  CAS  Google Scholar 

  • Gallart-Ayola H, Moyano E, Galceran MT (2010) Recent advances in mass spectrometry analysis of phenolic endocrine disruptors and related compounds. Mass Spectrom Rev 29:776–805

    Article  CAS  Google Scholar 

  • García-Lopez M, Rodríguez I, Cela R (2009) Pressurized liquid extraction of organophosphate triesters from sediment samples using aqueous solutions. J Chromatogr A 1216:6986–6993

    Article  CAS  Google Scholar 

  • German Federal Environment Agency (2003) Evaluation from the point of view of health of the presence in drinking water of substances that are not (yet) possible or only partially possible to evaluate. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 46:249–251 (in German)

    Article  Google Scholar 

  • German Federal Environment Agency (2011) Risk assessment of trichloramine in the air of indoor swimming pools. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 54:997–1004 (in German)

    Article  Google Scholar 

  • Giger W (2009) Hydrophilic and amphiphilic water pollutants: using advanced analytical methods for classic and emerging contaminants. Anal Bioanal Chem 393:37–44

    Article  CAS  Google Scholar 

  • Glassmeyer ST, Kolpin DW, Furlong ET, Focazio MT (2008) Environmental presence and persistence of pharmaceuticals: an overview. In: Aga DS (ed) Fate of pharmaceuticals in the environment and in water treatment systems. CRC Press, Boca Raton, pp 3–52

    Google Scholar 

  • Godejohann M, Heintz L, Daolio C, Berset J-D, Muff D (2009) Comprehensive non-targeted analysis of contaminated groundwater of a former ammunition destruction site using 1H-NMR and HPLC-SPE-NMR/TOF-MS. Environ Sci Technol 43:7055–7061

    Article  CAS  Google Scholar 

  • Gómez MJ, Gómez-Ramos MM, Agüera A, Mezcua M, Herrera S, Fernandez-Alba AR (2009) A new gas chromatography/mass spectrometry method for the simultaneous analysis of target and non-target organic contaminants in waters. J Chromatogr A 1216:4071–4082

    Article  CAS  Google Scholar 

  • Gómez MJ, Gómez-Ramos MM, Malato O, Mezcua M, Férnandez-Alba AR (2010) Rapid automated screening, identification and quantification of organic micro-contaminants and their main transformation products in wastewater and river waters using liquid chromatography–quadrupole–time-of-flight mass spectrometry with an accurate-mass database. J Chromatogr A 1217:7038–7054

    Article  CAS  Google Scholar 

  • Grigoriadou A, Schwarzbauer J, Georgakopoulos A (2008) Molecular indicators for pollution source identification in marine and terrestrial water of the industrial area of Kavala city, North Greece. Environ Poll 151:231–242

    Article  CAS  Google Scholar 

  • Gros M, Petrović M, Barceló D (2006) Multi-residue analytical methods using LC-tandem MS for the determination of pharmaceuticals in environmental and wastewater samples: a review. Anal Bioanal Chem 386:941–952

    Article  CAS  Google Scholar 

  • Grübel A, Schmidt W, Imhof L, Wagner M (2011) Disinfection by-products from amino acids—responsible for odour in tap water? Vom Wasser 109:75–81

    Google Scholar 

  • Guillarme D, Schappler J, Rudaz S, Veuthey J-L (2010) Coupling ultra-high-pressure liquid chromatography with mass spectrometry. TrAC-Trend Anal Chem 29:15–27

    Article  CAS  Google Scholar 

  • Hao C, Zhao X, Tabe S, Yang P (2008) Optimization of a multiresidual method for the determination of waterborne emerging organic pollutants using solid-phase extraction and liquid chromatography/tandem mass spectrometry and isotope dilution mass spectrometry. Environ Sci Technol 42:4068–4075

    Article  CAS  Google Scholar 

  • Hart DS, Davis LC, Erickson LE, Callender TM (2004) Sorption and partitioning parameter of benzotriazole compounds. Microchem J 77:9–17

    Article  CAS  Google Scholar 

  • Helbling DE, Hollender J, Kohler H-PE, Singer HP, Fenner K (2010a) High-throughput identification of microbial transformation products of organic micropollutants. Environ Sci Technol 44:6621–6627

    Article  CAS  Google Scholar 

  • Helbling DE, Hollender J, Kohler H-PE, Fenner K (2010b) Structure-based interpretation of biotransformation pathways of amide-containing compounds in sludge-seeded bioreactors. Environ Sci Technol 44:6628–6635

    Article  CAS  Google Scholar 

  • Hernández F, Biglsma L, Sancho JV, Diaz R, Ibáñez M (2011) Rapid wide-scope screening of drugs of abuse, prescription drugs with potential for abuse and their metabolites in influent and effluent urban wastewater by ultrahigh pressure liquid chromatography–quadrupole–time-of-flight mass spectrometry. Anal Chim Acta 684:87–97

    Article  CAS  Google Scholar 

  • Hery M, Hecht G, Gerber JM, Gendre JC, Hubert G, Rebuffaud J (1995) Exposure to chloramines in the atmosphere of indoor swimming pools. Ann Occupat Hygiene 39:427–439

    CAS  Google Scholar 

  • Hogenboom AC, van Leerdam JA, de Voogt (2009) Accurate mass screening and identification of emerging contaminants in environmental samples by liquid chromatography–hybrid linear ion trap Orbitrap mass spectrometry. J Chromatogr A 1216:510–519

    Article  CAS  Google Scholar 

  • Hoh E, Zhu L, Hites RA (2006) Dechlorane Plus, a chlorinated flame retardant, in the Great Lakes. Environ Sci Technol 40:1184–1189

    Article  CAS  Google Scholar 

  • Hollender J (2007) Micropollutants from urban drainage. Occurrences in Swiss waters and evaluation. GWA 11:843–852 (in German)

    Google Scholar 

  • Hu L, Martin HM, Arcs-Bulted O, Sugihara MN, Keatling KA, Strathmann TJ (2009) Oxidation of carbamazepine by Mn(VII) and Fe(VI): reaction kinetics and mechanism. Environ Sci Technol 43:509–515

    Article  CAS  Google Scholar 

  • Huy NV, Murakami M, Sakai H, Oguma K, Kosaka K, Asami M, Takizawa S (2011) Occurrence and formation potential of N-nitrosodimethylamine in ground water and river water in Tokyo. Water Res 45:3369–3377

    Article  CAS  Google Scholar 

  • Ibáñez M, Sancho JV, Hernández F, McMillan D, Rao R (2008) Rapid non-target screening of organic pollutants in water by ultraperformance liquid chromatography coupled to time-of-light mass spectrometry. TrAC-Trend Anal Chem 27:481–489

    Article  CAS  Google Scholar 

  • International Standard ISO 25101 (2009) Water quality—determination of perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA)—method for unfiltered samples using solid phase extraction and liquid chromatography/mass spectrometry

  • Jahnke A, Ahrens L, Ebinghaus R, Berger U, Barber JL, Temme C (2007) An improved method for the analysis of volatile polyfluorinated alkyl substances in environmental air samples. Anal Bioanal Chem 387:965–975

    Article  CAS  Google Scholar 

  • Janna H, Scrimshaw MD, Williams RJ, Churchley J, Stumpter JP (2011) From dishwasher to tap? Xenobiotic substances benzotriazole and tolyltriazole in the environment. Environ Sci Technol 45:3858–3864

    CAS  Google Scholar 

  • Jansson C, Kreuger J (2010) Multiresidue analysis of 95 pesticides at low nanogram/liter levels in surface waters using online preconcentration and high performance liquid chromatography/tandem mass spectrometry. J AOAC Int 93:1732–1747

    CAS  Google Scholar 

  • Jonkers N, Kohler H-PE, Dammshäuser A, Giger W (2009) Mass flows of endocrine disruptors in the Glatt River during varying weather conditions. Environ Poll 157:714–723

    Article  CAS  Google Scholar 

  • Jover E, Matamoros V, Bayona JM (2009) Characterization of benzothiazoles, benzotriazoles and benzosulfonamides in aqueous matrices by solid-phase extraction followed by comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry. J Chromatogr A 1216:4013–4019

    Article  CAS  Google Scholar 

  • Jurado-Sánchez B, Ballesteros E, Gallego M (2010) Screening of N-nitrosamines in tap and swimming pool waters using fast gas chromatography. J Sep Sci 33:610–616

    Article  CAS  Google Scholar 

  • Kawagoshi Y, Fukunaga I, Itoh H (1999) Distribution of organophosphoric acid triesters between water and sediment at a sea-based solid waste disposal site. J Mat Cycles Waste 1:53–61

    CAS  Google Scholar 

  • Kawagoshi Y, Nakamura S, Fukunaga I (2002) Degradation of organophosphoric esters in leachate from a sea-based solid waste disposal site. Chemosphere 48:219–225

    Article  CAS  Google Scholar 

  • Kern S, Fenner K, Singer HP, Schwarzenbach RP, Hollender J (2009) Identification of transformation products of organic contaminants in natural waters by computer-aided prediction and high resolution mass spectrometry. Environ Sci Technol 43:7039–7046

    Article  CAS  Google Scholar 

  • Kern S, Baumgartner R, Helbling DE, Hollender J, Singer H, Loos MJ, Schwarzenbach RP, Fenner K (2010) A tiered procedure for assessing the formation of biotransformation products of pharmaceuticals and biocides during activated sludge treatment. J Environ Monit 12:2100–2111

    Article  CAS  Google Scholar 

  • Kiss A, Fries E (2009) Occurrence of benzotriazoles in the rivers of Main, Hengstbach and Hegbach (Germany). Environ Sci Pollut Res 16:702–710

    Article  CAS  Google Scholar 

  • Kiss A, Fries E (2012) Seasonal source influence on river mass flows of benzotriazoles. J Environ Monit. doi:10.1039/C2EM10826G

  • Kloepfer A, Jekel M, Reemtsma T (2004) Determination of benzothiazoles from complex aqueous samples by liquid chromatography–mass spectrometry following solid-phase extraction. J Chromatogr A 1058:81–88

    CAS  Google Scholar 

  • Kloepfer A, Jekel M, Reemtsma T (2005) Occurrence, sources, and fate of benzothiazoles in municipal wastewater treatment plants. Environ Sci Technol 39:3792–3798

    Article  CAS  Google Scholar 

  • Klontza EE, Konkouraki EE, Diamadopoulos E (2010) Determination of nonylphenol ethoxylates in wastewater samples with SPME/GC-MS. Desal Water Treat 23:80–88

    Article  CAS  Google Scholar 

  • Kolic TM, Shen L, MacPherson K, Fayez L, Gobran T, Helm PA, Marvin CH, Arsenault G, Reiner EJ (2009) The analysis of halogenated flame retardants by GC-HRMS in environmental samples. J Chromatogr Sci 47:83–91

    CAS  Google Scholar 

  • Kormos JL, Schulz M, Kohler H-PE, Ternes TA (2010) Biotransformation of selected iodinated X-ray contrast media and characterization of microbial transformation pathways. Environ Sci Technol 44:4998–5007

    Article  CAS  Google Scholar 

  • Korytar P, Parera J, Leonards PEG, Santos FJ, de Boer J, Brinkman UAT (2005) Characterization of polychlorinated n-alkanes using comprehensive two-dimensional gas chromatography–electron-capture negative ionization time-of-flight spectrometry. J Chromatogr A 1086:71–82

    Article  CAS  Google Scholar 

  • Krauss M, Hollender J (2008) Analysis of nitrosamines in wastewater: exploring the trace level quantification capabilities of a hybrid linear ion trap/orbitrap mass spectrometer. Anal Chem 80:834–842

    Article  CAS  Google Scholar 

  • Krauss M, Singer HP, Hollender J (2010) LC-high resolution MS in environmental analysis: from target screening to the identification of unknowns. Anal Bioanal Chem 397:943–951

    Article  CAS  Google Scholar 

  • Kumar A, Xagoraraki I (2010) Pharmaceuticals, personal care products and endocrine-disrupting chemicals in U.S. surface and finished drinking waters: a proposed ranking system. Sci Total Environ 408:5972–5989

    Article  CAS  Google Scholar 

  • Lara-Martin PA, Gonzalez-Mazo E, Brownawell BJ (2011) Multi-residue method for the analysis of synthetic surfactants and their degradation metabolites in aquatic systems by liquid chromatography–time-of-flight-mass spectrometry. J Chromatogr A 1218:4799–4807

    Article  CAS  Google Scholar 

  • Lee C, Schmidt C, Yoon J, von Gunten U (2007a) Oxidation of N-nitrosodimethylamine (NDMA) precursors with ozone and chlorine dioxide: kinetics and effect on NDMA formation potential. Environ Sci Technol 41:2056–2063

    Article  CAS  Google Scholar 

  • Lee C, Yoon J, von Gunten U (2007b) Oxidative degradation of N-nitrosodimethylamine by conventional ozonation and the advanced oxidation process ozone/hydrogen peroxide. Water Res 41:581–590

    Article  CAS  Google Scholar 

  • Lei YD, Wania F, Mathers D, Mabury SA (2004) Determination of vapour pressures, octanol-air, and water-air partition coefficients for polyfluorinated sulfonamide, sulfonamidoethanols, and telomere alcohols. J Chem Eng Data 49:1013–1022

    Article  CAS  Google Scholar 

  • Lien G-W, Chen C-Y, Wang G-S (2009) Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization for determining estrogenic chemicals in water by liquid chromatography tandem mass spectrometry with chemical derivatizations. J Chromatogr A 1216:956–966

    Article  CAS  Google Scholar 

  • Loos R, Locoro G, Comero S, Contini S, Schwesig D, Werres F, Balsaa P, Gans O, Weiss S, Blaha L, Bolchi M, Gawlik BM (2010) Pan-European survey on the occurrence of selected polar organic persistent pollutants in ground-water. Water Res 44:4115–4126

    Article  CAS  Google Scholar 

  • López P, Brandsma SA, Leonards PEG, de Boer J (2009) Methods for determination of phenolic brominated flame retardants, and by-products, formulation intermediates and decomposition products of brominated flame retardants in water. J Chromatogr A 1216:334–345

    Article  CAS  Google Scholar 

  • Luo S, Fang L, Wang X, Liu H, Ouyang G, Lan C, Luan T (2010) Determination of octylphenol and nonylphenol in aqueous sample using simultaneous derivatization and dispersive liquid–liquid microextraction followed by gas chromatography–mass spectrometry. J Chromatogr A 1217:6762–6768

    Article  CAS  Google Scholar 

  • Mahmoud MAM, Kärrman A, Oono S, Harada KH, Koizumi A (2009) Polyfluorinated telomers in precipitation and surface water in an urban area of Japan. Chemosphere 74:467–472

    Article  CAS  Google Scholar 

  • Makris KC, Snyder SA (2010) Screening of pharmaceuticals and endocrine disrupting compounds of water supplies of Cyphus. Water Sci Technol 62:2720–2728

    Article  CAS  Google Scholar 

  • Martin JW, Asher BJ, Beesoon S, Benskin JP, Ross MS (2010) PFOS or PreFOS? Are perfluorooctane sulfonate precursors (PreFOS) important determinants of human and environmental perfluorooctane sulfonate (PFOS) exposure? J Environ Monit 12:1979–2004

    Article  CAS  Google Scholar 

  • Martínez-Carballo E, González-Barreiro C, Sitka A, Scharf S, Gans O (2007) Determination of selected organophosphate esters in the aquatic environment of Austria. Sci Total Environ 388:290–299

    Article  CAS  Google Scholar 

  • Matamoros V, Jover E, Bayona JM (2009) Advances in the determination of degradation intermediates of personal care products in environmental matrixes: a review. Anal Bioanal Chem 393:847–860

    Article  CAS  Google Scholar 

  • Moliner-Martinez Y, Molins-Legua C, Verdú-Andrés J, Herráez-Hernández R, Campins-Falcó P (2011) Advantages of monolithic over particulate columns for multiresidue analysis of organic pollutants by in-tube solid-phase microextraction coupled to capillary liquid chromatography. J Chrom A 1218:6256–6262

    Article  CAS  Google Scholar 

  • Möller A, Xie Z, Sturm R, Ebinghaus R (2010) Large-scale distribution of Dechlorane Plus in air and seawater from the Arctic to Antarctica. Environ Sci Technol 44:8977–8982

    Article  CAS  Google Scholar 

  • Morales TV, Padrón MET, Ferrera ZS, Rodriguez JJS (2009) Determination of alkylphenol ethoxylates and their degradation products in liquid and solid samples. TrAc-Trend Anal Chem 28:1186–1200

    Article  CAS  Google Scholar 

  • Moriya Y, Shigemizu D, Hattori M, Tokimatsu T, Kotera M, Goto S, Kaneshisa M (2010) PathPred: an enzyme-catalyzed metabolic pathway prediction server. Nucleic Acids Res 38(suppl 2):W138–W143

    Article  CAS  Google Scholar 

  • Muellner MG, Wagner ED, McCalla K, Richardson SD, Woo Y-T, Plewa MJ (2007) Haloacetonitriles vs. regulated haloacetic acids: are nitrogen-containing DBPs more toxic? Environ Sci Technol 41:645–651

    Article  CAS  Google Scholar 

  • Muir DCG, Yarechewski AL, Grift NP (1983) Environmental dynamics of phosphate esters. III. Comparison of the bioconcentration of four triaryl phosphates by fish. Chemosphere 12:155–166

    Article  CAS  Google Scholar 

  • Muscalu AM, Reiner EJ, Liss SN, Chen T, Ladwig G, Morse D (2011) A routine accredited method for the analysis of polychlorinated biphenyls, organochlorine pesticides, chlorobenzenes and screening of other halogenated organics in soil, sediment and sludge by GCxGC-μECD. Anal Bioanal Chem 401:2403–2413

    Article  CAS  Google Scholar 

  • Nawrocki J, Andrzejewski P (2011) Nitrosamines and water. J Hazard Mater 189:1–18

    Article  CAS  Google Scholar 

  • Neumann S, Böcker S (2010) Computational mass spectrometry for metabolomics: identification of metabolites and small molecules. Anal Bioanal Chem 398:2779–2788

    Article  CAS  Google Scholar 

  • Ni HG, Lu FH, Luo XL, Tian HY, Zeng EY (2008) Occurrence, phase distribution, and mass loadings of benzothiazoles in riverine runoff of the pearl river delta, China. Environ Sci Technol 42:1892–1897

    Article  CAS  Google Scholar 

  • Nödler K, Licha T, Bester K, Sauter M (2010) Development of a multi-residue analytical method, based on liquid chromatography–tandem mass spectrometry, for the simultaneous determination of 46 micro-contaminants in aqueous samples. J Chromatogr A 1217:6511–6521

    Article  CAS  Google Scholar 

  • Núnez L, Wiedmer SK, Parshintsev J, Hartonen K, Riekkola M-L, Tadeo JL, Turiel E (2009) Determination of nonylphenol and nonylphenol ethoxylates by MEKC. J Sep Sci 32:2109–2116

    Article  CAS  Google Scholar 

  • OxyChem (2011) Dechlorane Plus Manual, http://www.oxy.com/OurBusinesses/Chemicals/Products/Documents/dechloraneplus/dechlorane_plus.pdf (accessed 13 May 2011)

  • Oya M, Kosaka K, Asami M, Kunikane S (2008) Formation of N-nitrosodimethylamine (NDMA) by ozonation of dyes and related compounds. Chemosphere 73:1724–1730

    Article  CAS  Google Scholar 

  • Peng X-T, Shi Z-G, Feng Y-Q (2011) Rapid and high-throughput determination of cationic surfactants in environmental water samples by automated on-line polymer monolith microextraction coupled to high performance liquid chromatography–mass spectrometry. J Chromatogr A 1218:3588–3594

    Article  CAS  Google Scholar 

  • Pereira RO, de Alda ML, Joglar J, Daniel LA, Barceló D (2011) Identification of new ozonation disinfection byproducts of 17β-estradiol and estrone in water. Chemosphere 84:1535–1541

    Article  CAS  Google Scholar 

  • Petri M, Jiang J-Q, Maier M (2010) Proficiency test of non-target screening with gas chromatography mass spectrometry to confirm a detected contamination of raw and drinking water. Water Sci Technol 10:806–814

    Article  CAS  Google Scholar 

  • Petrovic M, Farré M, de Alda ML, Perez S, Postigo C, Köck M, Radjenovic J, Gros M, Barceló D (2010) Recent trends in the liquid chromatography–mass spectrometry analysis of organic contaminants in environmental samples. J ChromA 1217:4004–4017

    Article  CAS  Google Scholar 

  • Pitarch E, Portolés T, Marin JM, Ibáñez M, Albarrán F, Hernández F (2010) Analytical strategy based on the use of liquid chromatography and gas chromatography with triple–quadrupole and time-of-flight MS analyzers for investigating organic contaminants in wastewater. Anal Bioanal Chem 397:2763–2776

    Article  CAS  Google Scholar 

  • Pitter P, Chudoba J (1990) Biodegradability of organic substances in the aquatic environment. CRC Press, Boca Raton

    Google Scholar 

  • Planas C, Palacios O, Ventura F, Rivera J, Caixach J (2008) Analysis of nitrosamines in water by automated SPE and isotope dilution GC/HRMS. Talanta 76:906–913

    Article  CAS  Google Scholar 

  • Portolés T, Pitarch E, López FJ, Hernández F (2011) Development and validation of a rapid and wide-scope qualitative screening method for detection and identification of organic pollutants in natural water and wastewater by gas chromatography time-of-flight mass spectrometry. J Chromatogr A 1218:303–315

    Article  CAS  Google Scholar 

  • Pozzi R, Bocchini P, Pinelli F, Galletti GC (2011) Determination of nitrosamines in water by gas chromatography/chemical ionization/selective ion trapping mass spectrometry. J Chromatogr A 1218:1808–1814

    Article  CAS  Google Scholar 

  • Prasse C, Wagner M, Schulz R, Ternes TA (2011) Biotransformation of the antiviral drugs acyclovir and penciclovir in activated sludge treatment. Environ Sci Technol 45:2761–2769

    Article  CAS  Google Scholar 

  • Prieto A, Schrader S, Möder M (2010) Determination of organic priority pollutants and emerging compounds in wastewater and snow samples using multiresidue protocols on the basis of microextraction by packed sorbents coupled to large volume injection gas chromatography–mass spectrometry analysis. J Chromatogr A 1217:6002–6011

    Article  CAS  Google Scholar 

  • Qiu XH, Hites RA (2008) Dechlorane Plus and other flame retardants in tree bark from the Northeastern United States. Environ Sci Technol 42:31–36

    Article  CAS  Google Scholar 

  • Quintana JB, Rodil R, Reemtsma T, Garcia-Lopez M, Rodriguez I (2008) Organophosphorus flame retardants and plasticizers in water and air II. Analytical methodology. TrAC-Trend Anal Chem 27:904–915

    Article  CAS  Google Scholar 

  • Quintana JB, Rodil R, Lopez-Mahia P, Muniategui-Lorenzo S, Prada-Rodriguez D (2010) Investigating the chlorination of acidic pharmaceuticals and by-product formation aided by an experimental design methodology. Water Res 44:243–255

    Article  CAS  Google Scholar 

  • Radjenović J, Petrović M, Barceló D (2009) Complementary mass spectrometry and bioassays for evaluating pharmaceutical-transformation products in treatment of drinking water and wastewater. TrAC-Trend Anal Chem 28:562–580

    Article  CAS  Google Scholar 

  • Reemtsma T, Jekel M (eds) (2006) Organic pollutants in the water cycle. Wiley-VCH, Weinheim

    Google Scholar 

  • Reemtsma T, Weiss S, Müller J, Petrovic M, González S, Barcelo D, Ventura F, Knepper TP (2006) Polar pollutants entry into the water cycle by municipal wastewater: a European perspective. Environ Sci Technol 40:5451–5458

    Article  CAS  Google Scholar 

  • Reemtsma T, Quintana JB, Rodil R, García-López M, Rodríguez I (2008) Organophosphorus flame retardants and plasticizers in water and air I. Occurrence and fate. TrAC-Trend Anal Chem 27:727–737

    Article  CAS  Google Scholar 

  • Reemtsma T, Miehe U, Duennbier U, Jekel M (2010) Polar pollutants in municipal wastewater and the water cycle: occurrence and removal of benzotriazoles. Water Res 44:596–604

    Article  CAS  Google Scholar 

  • Richardson SD (2010) Environmental mass spectrometry: emerging contaminants and current issues. Anal Chem 82:4742–4774

    Article  CAS  Google Scholar 

  • Richardson SD, Ternes TA (2011) Water analysis: emerging contaminants and current issues. Anal Chem 83:4614–4648

    Article  CAS  Google Scholar 

  • Richardson SD, Plewa MJ, Wagner ED, Schoeny R, DeMarini DM (2007) Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: a review and roadmap for research. Mutat Res-Rev Mutat 636:178–242

    Article  CAS  Google Scholar 

  • Richardson SD, DeMarini DM, Kogevinas M, Fernandez P, Marco E, Lourencetti C, Balleste C, Heederik D, Meliefste K, McKague AB, Marcos R, Font-Ribera L, Grimalt JO, Villanueva CM (2010) What is in the pool? A comprehensive identification of disinfection by-products and assessment of mutagenicity of chlorinated and brominated swimming pool water. Environ Health Persp 118:1523–1530

    Article  CAS  Google Scholar 

  • Rodil R, Quintana JB, Lopez-Mahia P, Muniategui-Lorenzo S, Prada-Rodriguez D (2009) Multi-residue analytical method for the determination of emerging pollutants in water by solid-phase extraction and liquid chromatography–tandem mass spectrometry. J Chromatogr A 1216:2958–2969

    Article  CAS  Google Scholar 

  • Rodríguez I, Calvo F, Quintana JB, Rubí E, Rodil R, Cela R (2006) Suitability of solid-phase microextraction for the determination of organophosphate flame retardants and plasticizers in water samples. J Chromatogr A 1108:158–165

    Article  CAS  Google Scholar 

  • Rosal R, Rodriguez A, Perdigon-Melon JA, Petre A, Garcia-Calvo E, Gomez MJ, Aguera A, Fernandez-Alba AR (2010) Occurrence of emerging pollutants in urban wastewater and their removal through biological treatment followed by ozonation. Water Res 44:578–588

    Article  CAS  Google Scholar 

  • Sánchez-Avila J, Quintana J, Ventura F, Tauler R, Duarte CM, Lacorte S (2010) Stir bar sorptive extraction–thermal desorption–gas chromatography–mass spectrometry: an effective tool for determining persistent organic pollutants and nonyphenol in coastal waters in compliance with existing directives. Mar Pollut Bull 60:103–112

    Article  CAS  Google Scholar 

  • Scheurer M, Godejohann M, Wick A, Happel O, Ternes TA, Brauch H-J, Ruck WKL, Lange FT (2011) Structural elucidation of main ozonation products of the artificial sweeteners cyclamate and acesulfame. Environ Sci Pollut. doi:10.1007/s11536-011-0618-X

  • Schmalz C, Frimmel FH, Zwiener C (2011a) Trichloramine in swimming pools—formation and mass transfer. Water Res 45:2681–2690

    Article  CAS  Google Scholar 

  • Schmalz C, Wunderlich HG, Heinze R, Frimmel FH, Zwiener C, Grummt T (2011b) Application of an optimized system for the well-defined exposure of human lung cells to trichloramine and indoor pool air. J Water Health 9:586–596

    Article  CAS  Google Scholar 

  • Schmidt CK, Brauch H-J (2008) N, N-dimethylsulfamide as precursor for N-nitrosodimethylamine (NDMA) formation upon ozonation and its fate during drinking water treatment. Environ Sci Technol 42:6340–6346

    Article  CAS  Google Scholar 

  • Schreiber MI, Mitch WA (2006) Occurrence and fate of nitrosamines and nitrosamine precursors in wastewater-impacted surface waters using boron as a conservative tracer. Environ Sci Technol 40:3203–3210

    Article  CAS  Google Scholar 

  • Schwarzbauer J, Ricking M (2010) Non-target screening analysis of river water as a compound-related base for monitoring measures. Environ Sci Pollut Res 17:934–947

    Article  CAS  Google Scholar 

  • Schymanski EL, Schulze T, Hermanns J, Brack W (2011) Computer tools for structure elucidation in EDA. In: Brack W (ed) Handbook of environmental chemistry. vol 15: 167-198

  • Shaw SD, Blum A, Weber R, Kannan K, Rich D, Lucas D, Koshland CP, Dobraca D, Hanson S, Birnbaum LS (2010) Halogenated flame retardants: do the fire safety benefits justify the risks? Rev Environ Health 25:261–305

    Article  CAS  Google Scholar 

  • Sinclair CJ, Boxall ABA (2003) Assessing the ecotoxicity of pesticide transformation products. Environ Sci Technol 37:4617–4625

    Article  CAS  Google Scholar 

  • Skoczynska E, Korytar P, de Boer J (2008) Maximizing chromatographic information from environmental extracts by GCxGC-TOF-MS. Environ Sci Technol 42:6611–6618

    Article  CAS  Google Scholar 

  • Skutlarek D, Exner M, Färber H (2006) Perfluorinated surfactants in surface and drinking waters. Environ Sci Pollut Res 13:299–307

    Article  CAS  Google Scholar 

  • Spies RB, Andresen BD, Rice DW (1987) Benzothiazoles in estuarine sediments as indicators of street runoff. Nature 327:697–699

    Article  CAS  Google Scholar 

  • Sverko E, Reiner EJ, Tomy GT, McGrindle R, Shen L, Arsenault G, Zaruk D, MacPherson K, Marvin CH, Helm PA, McCarry BE (2010) Compounds structurally related to Dechlorane Plus in sediment and biota from Lake Ontario (Canada). Environ Sci Technol 44:574–579

    Article  CAS  Google Scholar 

  • Sverko E, Tomy GT, Reiner EJ, Li Y-F, McCarry BE, Arnot JA, Law RJ, Hites RA (2011) Dechlorane Plus and related compounds in the environment: a review. Environ Sci Technol 45:5088–5098

    Article  CAS  Google Scholar 

  • Tamtam F, Mercier F, Eurin J, Chevreuil M, Le Bot B (2009) Ultra performance liquid chromatography tandem mass spectrometry performance evaluation for analysis of antibiotics in natural waters. Anal Bioanal Chem 393:1709–1718

    Article  CAS  Google Scholar 

  • Taniyasu S, Kannan K, So MK, Gulkowska A, Sinclair E, Okazawa T, Yamashita N (2005) Analysis of fluorotelomer alcohols, fluorotelomer acids, and short- and long-chain perfluorinated acids in water and biota. J Chromatogr A 1093:89–97

    Article  CAS  Google Scholar 

  • Terzic S, Ahel M (2011) Nontarget analysis of polar contaminants in freshwater sediments influenced by pharmaceutical industry using ultra-high-pressure liquid chromatography–quadrupole time-of-flight mass spectrometry. Environ Pollut 159:557–566

    Article  CAS  Google Scholar 

  • U.S. EPA (1997) Exposure factors handbook. DCN 20460. U.S. Environmental Protection Agency, Washington, DC

    Google Scholar 

  • van Leerdam JA, Hogeboom AC, van der Kooi MME, de Voogt P (2009) Determination of polar 1H-benzotriazoles and benzothiazoles in water by solid-phase extraction and liquid chromatography LTQ FT Orbitrap mass spectrometry. J Mass Spectrom 282:99–107

    Article  CAS  Google Scholar 

  • Van Leeuwen SPJ, Swart JP, van der Veen I, de Boer J (2009) Significant improvements in the analysis of perfluorinated compounds in water and fish: results from an interlaboratory method evaluation study. J Chromatogr A 1216:401–409

    Article  CAS  Google Scholar 

  • Van Zelm R, Huijbregts MAJ, Van De Meent D (2010) Transformation products in the life cycle impact assessment of chemicals. Environ Sci Technol 44:1004–1009

    Article  CAS  Google Scholar 

  • Vazquez-Roig P, Andreu V, Blasco C, Picó Y (2009) SPE and LC-MS/MS determination of 14 illicit drugs in surface waters from the Natural Park of L'Albufera (València, Spain). Anal Bioanal Chem 397:2851–2864

    Article  CAS  Google Scholar 

  • Vega-Morales T, Sosa-Ferrera Z, Santana-Rodriguez JJ (2010) Determination of alkylphenol polyethoxylates, bisphenol-A, 17α-ethynylestradiol and 17β-estradiol and its metabolites in sewage samples by SPE and LC/MS/MS. J Hazard Mater 183:701–711

    Article  CAS  Google Scholar 

  • von Gunten U, Salhi E, Schmidt CK, Arnold WA (2010) Kinetics and mechanisms of N-nitrosodimethylamine formation upon ozonation of N, N-dimethylsulfamide-containing waters: bromide catalysis. Environ Sci Technol 44:5762–5768

    Article  CAS  Google Scholar 

  • Walse SS, Mitch WA (2008) Nitrosamine carcinogens also swim in chlorinated pools. Environ Sci Technol 42:1032–1037

    Article  CAS  Google Scholar 

  • Wang W, Ren S, Zhang H, Yu J, An W, Hu J, Yang M (2011) Occurrence of nine nitrosamines and secondary amines in source water and drinking water: potential of secondary amines as nitrosamine precursors. Water Res 45:4930–4938

    Article  CAS  Google Scholar 

  • Weaver WA, Li J, Wen Y, Johnston J, Blatchley MR, Blatchley ER III (2009) Volatile disinfection by-product analysis from chlorinated indoor swimming pools. Water Res 43:3308–3318

    Article  CAS  Google Scholar 

  • Weiss S, Reemtsma T (2005) Determination of benzotriazole corrosion inhibitors from aqueous environmental samples by liquid chromatography–electrospray ionization–tandem mass spectrometry. Anal Chem 77:7415–7420

    Article  CAS  Google Scholar 

  • Weiss S, Jakobs J, Reemtsma T (2006) Discharge of three benzotriazole corrosion inhibitors with municipal wastewater and improvements by membrane bioreactor treatment and ozonation. Environ Sci Technol 40:7193–7199

    Article  CAS  Google Scholar 

  • Wick A, Wagner M, Ternes TA (2011) Elucidation of the transformation pathway of the opium alkaloid codeine in biological wastewater treatment. Environ Sci Technol 45:2761–2769

    Article  CAS  Google Scholar 

  • Yuan F, Hu C, Hu XX, Qu JH, Yang M (2009) Degradation of selected pharmaceuticals in aqueous solution with UV and UV/H2O2. Water Res 43:1766–1774

    Article  CAS  Google Scholar 

  • Zhao Y-Y, Boyd J, Hrudey SE, Li X-F (2006) Characterization of new nitrosamines in drinking water using liquid chromatography tandem mass spectrometry. Environ Sci Technol 40:7636–7641

    Article  CAS  Google Scholar 

  • Zhao Y-Y, Boyd JM, Woodbeck M, Andrews RC, Qin F, Hrudey SE, Li X-F (2008) Formation of N-nitrosamines from eleven disinfection treatments of seven different surface waters. Environ Sci Technol 42:4857–4862

    Article  CAS  Google Scholar 

  • Zhao YY, Liu X, Boyd JM, Qin F, Li J, Li XF (2009) Identification of N-nitrosamines in treated drinking water using nanoelectrospray ionization high-field asymmetric waveform ion mobility spectrometry with quadrupole time-of-flight mass spectrometry. J Chromatogr Sci 47:92–96

    Google Scholar 

  • Zhao Y, Qin F, Boyd JM, Anichina J, Li X-F (2010) Characterization and determination of chloro- and bromo-benzoquinones as new chlorination disinfection byproducts in drinking water. Anal Chem 82:4599–4605

    Article  CAS  Google Scholar 

  • Zhou W-J, Boyd JM, Qin F, Hrudey SE, Li X-F (2009) Formation of N-nitrosodiphenylamine and two new N-containing disinfection byproducts from chloramination of water containing diphenylamine. Environ Sci Technol 43:8443–8448

    Article  CAS  Google Scholar 

  • Zhou SN, Reiner EJ, Marvin C, Kolic T, Riddell N, Helm P, Dorman F, Misselwitz M, Brindle ID (2010) Liquid chromatography–atmospheric pressure photoionization tandem mass spectrometry for analysis of 36 halogenated flame retardants in fish. J Chromatogr A 1217:633–641

    Article  CAS  Google Scholar 

  • Zhou Q, Gao Y, Xie G (2011) Determination of bisphenol A, 4-n-nonylphenol, and 4-tert-octylphenol by temperature-controlled ionic liquid dispersive liquid-phase microextraction combined with high performance liquid chromatography-fluorescence detector. Talanta 83:1598–1602

    Article  CAS  Google Scholar 

  • Zwiener C (2007) Occurrence and analysis of pharmaceuticals and their transformation products in drinking water treatment. Anal Bioanal Chem 387:1159–1162

    Article  CAS  Google Scholar 

  • Zwiener C, Frimmel FH (2004) LC-MS analysis in the aquatic environment and in water treatment technology—a critical review—part II: applications for emerging contaminants and related pollutants, microorganisms and humic acids. Anal Bioanal Chem 378:862–874

    Article  CAS  Google Scholar 

  • Zwiener C, Richardson SD (2005) Analysis of disinfection by-products in drinking water by LC-MS and related MS techniques. TrAC-Trend Anal Chem 24:613–621

    Article  CAS  Google Scholar 

  • Zwiener C, Richardson SD, De Marini DM, Grummt T, Glauner T, Frimmel FH (2007) Drowning in disinfection byproducts? Assessing swimming pool water. Environ Sci Technol 41:363–372

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Analytical and Ecological Chemistry, University of Trier, Behringstr. 21, 54296, Trier, Germany

    Klaus Fischer

  2. Institute of Environmental Systems Research, University of Osnabrück, Barbarastr. 12, 49076, Osnabrück, Germany

    Elke Fries

  3. Unit Analysis of Organic Compounds, Bavarian Environment Agency, Bürgermeister-Ulrich-Str. 160, 86179, Augsburg, Germany

    Wolfgang Körner

  4. Environmental Analytical Chemistry, Center for Applied Geoscience (ZAG), Eberhard Karls University Tübingen, Hölderlinstr. 12, 72074, Tübingen, Germany

    Christina Schmalz & Christian Zwiener

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  1. Klaus Fischer
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  2. Elke Fries
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  3. Wolfgang Körner
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  4. Christina Schmalz
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  5. Christian Zwiener
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Correspondence to Klaus Fischer.

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Fischer, K., Fries, E., Körner, W. et al. New developments in the trace analysis of organic water pollutants. Appl Microbiol Biotechnol 94, 11–28 (2012). https://doi.org/10.1007/s00253-012-3929-z

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