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The many faces of sickle cell disease in children: complications in the appendicular skeleton

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Abstract

Sickle cell disease (SCD) is a hereditary red cell disorder with clinical manifestations secondary to sickling or crescent-shaped distortion of the red blood cells. Musculoskeletal complications of SCD are often the main causes for acute and chronic morbidities in children with manifestations including osteomyelitis, osteoporosis and osteonecrosis. This article aims to familiarise the paediatric radiologist with appendicular skeletal complications of SCD in the paediatric population and their imaging appearance.

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Authors and Affiliations

  1. Everlight Radiology, London, UK

    Marcela De La Hoz Polo

  2. Radiology Department, King’s College Hospital, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK

    Victoria E. Hudson & Saira Haque

  3. Radiology Department, St George’s University Hospital, London, UK

    John Adu

  4. Department of Paediatric Haematology, King’s College Hospital, King’s College Hospital NHS Foundation Trust, London, UK

    Subarna Chakravorty

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  1. Marcela De La Hoz Polo
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  2. Victoria E. Hudson
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  4. Subarna Chakravorty
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Contributions

S.H. and M.P. conceptualised this article. M.P., V.H., S.H. and J.A. drafted and revised the manuscript. M.P., J.A. and S.H. reviewed the manuscript. All authors approved the final manuscript for submission.

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Correspondence to Saira Haque.

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De La Hoz Polo, M., Hudson, V.E., Adu, J. et al. The many faces of sickle cell disease in children: complications in the appendicular skeleton. Pediatr Radiol (2024). https://doi.org/10.1007/s00247-024-05913-9

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