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Pacing Induced Ventricular Dysfunction in a Child: Improvement with Reduction in Paced Rate

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Abstract

Right ventricular (RV) pacing can be associated with impairment of left ventricular (LV) function due to electrical dyssynchrony and myocardial remodeling (Janousek et al. in J Cardiovasc Electrophysiol 15:470–474, 2004). RV-pacing induced ventricular dysfunction is reversible by techniques such as biventricular pacing and LV apical or LV free wall pacing or turning the pacemaker off which have all been shown to restore synchrony and improve left ventricular function (Janousek et al. in J Cardiovasc Electrophysiol 15:470–474, 2004; Geldorp et al. in Heart Fail Rev 16:305–314, 2011). We describe an infant with RV-pacing induced cardiomyopathy who improved when the pacing rate was reduced thus demonstrating the relationship between pacing rate and development of LV dysfunction.

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References

  1. Janousek J, Tomek V, Chaloupecky V, Gebauer RA (2004) Dilated cardiomyopathy associated with dual-chamber pacing in infants: improvement through either left ventricular cardiac resynchronization or programming the pacemaker off allowing intrinsic normal conduction. J Cardiovasc Electrophysiol 15:470–474

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  2. Geldorp IE, Vanagt WY, Prinzen FW, Delhaas T (2011) Chronic ventricular pacing in children: toward prevention of pacing-induced heart disease. Heart Fail Rev 16:305–314

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Authors and Affiliations

  1. Division of Cardiology, Department of Pediatrics, Oregon Health & Science University, 3181 SW Sam Jackson Rd, Portland, OR, 97239, USA

    Shilpi Garg & Seshadri Balaji

Authors
  1. Shilpi Garg
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  2. Seshadri Balaji
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Correspondence to Shilpi Garg.

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Conflict of interest

Seshadri Balaji is a recipient of a researcher-initiated grant from Medtronic.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was not obtained because it is retrospective case report.

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Garg, S., Balaji, S. Pacing Induced Ventricular Dysfunction in a Child: Improvement with Reduction in Paced Rate. Pediatr Cardiol 38, 1309–1310 (2017). https://doi.org/10.1007/s00246-017-1629-2

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  • DOI: https://doi.org/10.1007/s00246-017-1629-2

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