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Spectrophotometric Analysis in Umbilical Cords of Infants with Meconium Aspiration Syndrome

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Abstract

We compared spectrophotometric analysis of the umbilical cords of infants with meconium aspiration syndrome (MAS) or with meconium-stained amniotic fluid (MSAF) and healthy infants. In a prospective study, 15 infants with MAS and 37 infants with MSAF were enrolled. Twenty healthy infants formed a control group. The absorption peak of umbilical cords with meconium was significantly higher in the infants with MAS or MSAF than in controls. Spectrophotometric analysis of the umbilical cords with meconium may be useful to identify developed neonates with MAS or MSAF.

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References

  • Berkus MD, Langer O, Samueloff A, Xenakis EM, Field NT, Ridgway LE (1994) Meconium-stained amniotic fluid: increased risk for adverse neonatal outcome. Obstet Gynecol 84:115–120

    PubMed  CAS  Google Scholar 

  • Bhat RY, Rao A (2008) Meconium-stained amniotic fluid and meconium aspiration syndrome: a prospective study. Ann Trop Paediatr 28:199–203

    Article  PubMed  CAS  Google Scholar 

  • Castellheim A, Lindenskov PH, Pharo A, Fung M, Saugstad OD, Mollnes TE (2004) Meconium is a potent activator of complement in human serum and in piglets. Pediatr Res 55:310–318

    Article  PubMed  CAS  Google Scholar 

  • Cleary GM, Wiswell TE (1998) Meconium-stained amniotic fluid and the meconium aspiration syndrome. An update. Pediatr Clin North Am 45:511–529

    Article  PubMed  CAS  Google Scholar 

  • Dehan M, Francoual J, Londenbaum A (1978) Diagnosis of meconium aspiration by spectrophotometric analysis of urine. Arch Dis Child 53:74–76

    Article  PubMed  CAS  Google Scholar 

  • Gooding CA, Gregory GA (1971) Roentgenographic analysis of meconium aspiration of the newborn. Radiology 100:131–140

    PubMed  CAS  Google Scholar 

  • Grignaffini A, Soncini E, Ronzoni E, Piazza E, Anfuso S, Vadora E (2004) Meconium-stained amniotic fluid and fetal oxygen saturation measured by pulse oximetry during labour. Acta Biomed 75(Suppl 1):45–52

    PubMed  Google Scholar 

  • Karatekin G, Kesim MD, Nuhoğlu A (1999) Risk factors for meconium aspiration syndrome. Int J Gynaecol Obstet 65:295–297

    Article  PubMed  CAS  Google Scholar 

  • Khazardoost S, Hantoushzadeh S, Khooshideh M, Borna S (2007) Risk factors for meconium aspiration in meconium stained amniotic fluid. J Obstet Gynaecol 27:577–579

    Article  PubMed  CAS  Google Scholar 

  • Liu WF, Harrington T (2002) Delivery room risk factors for meconium aspiration syndrome. Am J Perinatol 19:367–378

    Article  PubMed  Google Scholar 

  • Maiya PP, Nagashree S, Shaik MS (2001) Role of score for neonatal acute physiology (SNAP) in predicting neonatal mortality. Indian J Pediatr 68:829–834

    Article  PubMed  CAS  Google Scholar 

  • Mitchell J, Schulman H, Fleischer A, Farmakides G, Nadeau D (1985) Meconium aspiration and fetal acidosis. Obstet Gynecol 65:352–355

    PubMed  CAS  Google Scholar 

  • Mollnes TE, Castellheim A, Lindenskov PH, Salvesen B, Saugstad OD (2008) The role of complement in meconium aspiration syndrome. J Perinatol 28(Suppl 3):116–119

    Article  Google Scholar 

  • Richardson DK, Gray JE, McCormick MC, Workman K, Goldmann DA (1993) Score for neonatal acute physiology: a physiologic severity index for neonatal intensive care. Pediatrics 91:617–623

    PubMed  CAS  Google Scholar 

  • Schrama AJ, de Beaufort AJ, Sukul YR, Jansen SM, Poorthuis BJ, Berger HM (2001) Phospholipase A2 is present in meconium and inhibits the activity of pulmonary surfactant: an in vitro study. Acta Paediatr 90:412–416

    Article  PubMed  CAS  Google Scholar 

  • Wen TS, Erikson NL, Blanco JD, Graham JM, Oshiro BT, Prieto JA (1993) Association of clinical intra-amniotic infection and meconium. Am J Perinatol 10:438–440

    PubMed  CAS  Google Scholar 

  • Yoder BA (1994) Meconium-stained amniotic fluid and respiratory complications: impact of selective tracheal suction. Obstet Gynecol 83:77–84

    PubMed  CAS  Google Scholar 

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Correspondence to Erdal Peker.

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Tuncer, O., Peker, E., Demir, N. et al. Spectrophotometric Analysis in Umbilical Cords of Infants with Meconium Aspiration Syndrome. J Membrane Biol 246, 525–528 (2013). https://doi.org/10.1007/s00232-013-9562-7

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  • DOI: https://doi.org/10.1007/s00232-013-9562-7

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