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Analysis of the evolution of the detection limits of electrochemical nucleic acid biosensors II

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Abstract

This critical review of electrochemical biosensors allowing direct detection of nucleic acid targets reports on different transduction pathways and their latest breakthroughs. A classification of the various strategies based on the nature of the electrochemical transduction is established to emphasize the efficiency of each of them. It provides an overall picture of the detection limit of the various approaches developed during the last two decades.

Detection limits evolutions of electrochemical DNA biosensors

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Acknowledgement

François-Xavier Guillon acknowledges support from the program Investissement d’Avenir launched by the French Government and implemented by Agence Nationale de la Recherche with reference ANR—IDEX-000-02 PSL for a PhD fellowship.

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  1. Unité de Technologies Chimiques et Biologiques pour la Santé, U 1022 INSERM, UMR 8258 CNRS. PSL Research University, Chimie ParisTech. Sorbonne Paris Cité, Université Paris Descartes, Faculté de Pharmacie de Paris, Paris, France

    Thu Huong Ho, François-Xavier Guillon, Pascal Bigey, Fethi Bedioui & Mathieu Lazerges

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Ho, T.H., Guillon, FX., Bigey, P. et al. Analysis of the evolution of the detection limits of electrochemical nucleic acid biosensors II. Anal Bioanal Chem 409, 4335–4352 (2017). https://doi.org/10.1007/s00216-017-0377-8

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