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The role of direct high-resolution mass spectrometry in foodomics

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Abstract

Foodomics has been defined as a global discipline in which advanced analytical techniques and bioinformatics are combined to address different questions in food science and nutrition. There is a growing number of works on the development and application of non-targeted omics methods in foodomics, which reflects that this emerging discipline is already considered by the scientific community to be a valuable approach to assess food safety, quality, and traceability as well as for the study of the links between food and health. As a result, there is a clear need for more rapid, high-throughput MS approaches for developing and applying non-targeted studies. Nowadays, direct MS analysis is one of the main choices to achieve high throughput, generating a set of information from the largest possible number of samples in a fast and straightforward way. The use of high- and ultrahigh-resolution MS greatly improves the analytical performance and offers a good combination of selectivity and sensitivity. By using a range of methods for direct sample introduction/desorption/ionization, high-throughput and non-target analysis of a variety of samples can be obtained in a few seconds by HRMS analysis. In this review, a general overview is presented of the main characteristics of direct HRMS-based approaches and their principal applications in foodomics.

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Acknowledgments

This work was supported by AGL2011-29857-C03-01 and AGL2014-53609-P projects (Ministerio de Economía y Competitividad, Spain). T. A. thanks the CAPES Foundation, Ministry of Education of Brazil for her predoctoral scholarship - Proc. N° 1532/13-8.

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Authors and Affiliations

  1. Laboratory of Foodomics, CIAL, CSIC, Nicolas Cabrera 9, 28049, Madrid, Spain

    Clara Ibáñez, Carolina Simó, Virginia García-Cañas, Tanize Acunha & Alejandro Cifuentes

  2. CAPES Foundation, Ministry of Education of Brazil, 70.040-020, Brasília, Distrito Federal do Brasil, Brazil

    Tanize Acunha

Authors
  1. Clara Ibáñez
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  2. Carolina Simó
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  3. Virginia García-Cañas
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  4. Tanize Acunha
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  5. Alejandro Cifuentes
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Correspondence to Carolina Simó.

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Published in the topical collection High-Resolution Mass Spectrometry in Food and Environmental Analysis with guest editor Aldo Laganà.

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Ibáñez, C., Simó, C., García-Cañas, V. et al. The role of direct high-resolution mass spectrometry in foodomics. Anal Bioanal Chem 407, 6275–6287 (2015). https://doi.org/10.1007/s00216-015-8812-1

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